Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: L(+)-TARTARIC ACID
PDB ligand accession: TLA
DrugBank: DB09459
PubChem: 444305
ChEMBL: CHEMBL1236315
InChI Key: FEWJPZIEWOKRBE-JCYAYHJZSA-N
SMILES: C(C(C(=O)O)O)(C(=O)O)O

ClassyFire chemical classification:

List of proteins that are targets for TLA

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P05231_TLA P05231 Interleukin-6 (IL-6) (B-cell n/a
2 Q6WZB0_TLA Q6WZB0 Alpha-ketoglutarate-dependent L-arginine hydroxylase n/a
3 P03072_TLA P03072 Large T antigen n/a
4 Q94AI7_TLA Q94AI7 Protein TOPLESS (WUS-interacting n/a
5 Q9I3W9_TLA Q9I3W9 Erythronate-4-phosphate dehydrogenase (EC n/a
6 A0A1S4NYE2_TLA A0A1S4NYE2 Beta-1,3-glucanase (EC 3.2.1.39) n/a
7 P18429_TLA P18429 Endo-1,4-beta-xylanase A (Xylanase n/a
8 P30046_TLA P30046 D-dopachrome decarboxylase (EC n/a
9 A0A0A0V023_TLA A0A0A0V023 Phosphonopyruvate hydrolase n/a
10 P31412_TLA P31412 V-type proton ATPase n/a
11 F9VNG5_TLA F9VNG5 Homoserine dehydrogenase (HDH) n/a
12 Q9NS75_TLA Q9NS75 Cysteinyl leukotriene receptor n/a
13 Q3KB33_TLA Q3KB33 glucarate dehydratase (EC n/a
14 Q4J3N3_TLA Q4J3N3 deleted n/a
15 Q9YEQ6_TLA Q9YEQ6 PUA domain-containing protein n/a
16 Q06121_TLA Q06121 Indole-3-glycerol phosphate synthase n/a
17 B4WBL8_TLA B4WBL8 deleted n/a
18 Q9SQT8_TLA Q9SQT8 Bifunctional 3-dehydroquinate dehydratase/shikimate n/a
19 P06873_TLA P06873 Proteinase K (EC n/a
20 Q96T68_TLA Q96T68 Histone-lysine N-methyltransferase SETDB2 n/a
21 Q8Y547_TLA Q8Y547 Lmo2229 protein n/a
22 O33599_TLA O33599 Glycyl-glycine endopeptidase LytM n/a
23 Q8TEK3_TLA Q8TEK3 Histone-lysine N-methyltransferase, H3 n/a
24 P53350_TLA P53350 Serine/threonine-protein kinase PLK1 n/a
25 F2RB83_TLA F2RB83 Alpha-N-dichloroacetyl-p-aminophenylserinol N-oxygenase (EC n/a
26 P60484_TLA P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase n/a
27 P0A2M9_TLA P0A2M9 MAPK phosphothreonine lyase n/a
28 Q3XZW8_TLA Q3XZW8 Glutamate racemase (EC n/a
29 Q9P2W7_TLA Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 n/a
30 Q53W95_TLA Q53W95 Alkaline phosphatase n/a
31 P50120_TLA P50120 Retinol-binding protein 2 n/a
32 P32021_TLA P32021 2-oxoglutarate-dependent ethylene/succinate-forming enzyme n/a
33 P0DTD1_TLA P0DTD1 Replicase polyprotein 1ab n/a
34 B0F481_TLA B0F481 Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic n/a
35 P21730_TLA P21730 C5a anaphylatoxin chemotactic n/a
36 O66186_TLA O66186 Thiocyanate hydrolase subunit n/a
37 D0E8I5_TLA D0E8I5 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) n/a
38 Q5EBY5_TLA Q5EBY5 laccase (EC 1.10.3.2) n/a
39 Q11198_TLA Q11198 (R)-specific enoyl-CoA hydratase n/a
40 Q9HTZ1_TLA Q9HTZ1 Murein tetrapeptide carboxypeptidase n/a
41 P53396_TLA P53396 ATP-citrate synthase (EC n/a
42 C8WR67_TLA C8WR67 Ketol-acid reductoisomerase (NADP(+)) n/a
43 Q5SI12_TLA Q5SI12 1,4-dihydroxy-6-naphtoate synthase (EC n/a
44 A0A084CH09_TLA A0A084CH09 deleted n/a
45 P14300_TLA P14300 ADP-ribosyl-[dinitrogen reductase] glycohydrolase n/a
46 O34798_TLA O34798 Peptidoglycan-N-acetylmuramic acid deacetylase n/a
47 P02884_TLA P02884 Thaumatin II (Thaumatin-2) n/a
48 B9JK80_TLA B9JK80 D-apiose dehydrogenase (EC n/a
49 A9JQL9_TLA A9JQL9 4,4'-diapophytoene synthase (DAP n/a
50 A6YEH4_TLA A6YEH4 CmnC n/a
51 A0A0H2YN38_TLA A0A0H2YN38 F5/8 type C n/a
52 A6Q234_TLA A6Q234 Aminodeoxyfutalosine deaminase (AFL n/a
53 F2Q7T0_TLA F2Q7T0 Bifunctional cytochrome P450/NADPH--P450 n/a
54 P35236_TLA P35236 Tyrosine-protein phosphatase non-receptor n/a
55 Q085A0_TLA Q085A0 Tryptophan halogenase n/a
56 Q5SJF5_TLA Q5SJF5 IMPACT family member n/a
57 P14789_TLA P14789 Protease LasA (EC n/a
58 G9Y2J2_TLA G9Y2J2 Histidine acid phosphatase n/a
59 Q2YP76_TLA Q2YP76 Substrate-binding region of n/a
60 Q13231_TLA Q13231 Chitotriosidase-1 (EC 3.2.1.14) n/a
61 Q70IY1_TLA Q70IY1 nebramycin 5' synthase n/a
62 Q00059_TLA Q00059 Transcription factor A, n/a
63 Q5ZUA2_TLA Q5ZUA2 Ectonucleoside triphosphate diphosphohydrolase n/a
64 P0AEY0_TLA P0AEY0 Maltose/maltodextrin-binding periplasmic protein n/a
65 A0A0P7JVD2_TLA A0A0P7JVD2 Beta-lactamase class C n/a
66 P0CG48_TLA P0CG48 Polyubiquitin-C [Cleaved into: n/a
67 Q8ZLV8_TLA Q8ZLV8 2-hydroxy-3-oxopropionate reductase (EC n/a
68 K5B7Z4_TLA K5B7Z4 Glucosyl-3-phosphoglycerate synthase (EC n/a
69 O27985_TLA O27985 CDP-alcohol phosphatidyltransferase AF-2299-like n/a
70 Q0P8W7_TLA Q0P8W7 Biotin carboxylase (EC n/a
71 P0DX98_TLA P0DX98 Cyclic dipyrimidine nucleotide n/a
72 Q51782_TLA Q51782 Phosphonoacetate hydrolase (EC n/a
73 Q88B84_TLA Q88B84 Peptidyl-prolyl cis-trans isomerase n/a
74 Q8C9A2_TLA Q8C9A2 Endonuclease V (EC n/a
75 O66188_TLA O66188 Thiocyanate hydrolase subunit n/a
76 Q9F4C9_TLA Q9F4C9 Restriction endonuclease n/a
77 A0A0D1FZV0_TLA A0A0D1FZV0 GAF domain-containing protein n/a
78 P03433_TLA P03433 Polymerase acidic protein n/a
79 O43583_TLA O43583 Density-regulated protein (DRP) n/a
80 P0A666_TLA P0A666 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase n/a
81 A0A060H1D7_TLA A0A060H1D7 Bacterio-rhodopsin/guanylyl cyclase 1 n/a
82 O75795_TLA O75795 UDP-glucuronosyltransferase 2B17 (UDPGT n/a
83 Q8D0U0_TLA Q8D0U0 Dihydrofolate synthase/folylpolyglutamate synthase n/a
84 Q9FH97_TLA Q9FH97 Protein ENHANCED PSEUDOMONAS n/a
85 P0A759_TLA P0A759 Glucosamine-6-phosphate deaminase (EC n/a
86 A5H660_TLA A5H660 histone deacetylase (EC n/a
87 P42260_TLA P42260 Glutamate receptor ionotropic, n/a
88 P14618_TLA P14618 Pyruvate kinase PKM n/a
89 P0A738_TLA P0A738 Cyclic pyranopterin monophosphate n/a
90 Q9H816_TLA Q9H816 5' exonuclease Apollo n/a
91 P0CG29_TLA P0CG29 Glutathione S-transferase theta-2 n/a
92 P37672_TLA P37672 2,3-diketo-L-gulonate reductase (2,3-DKG n/a
93 P22734_TLA P22734 Catechol O-methyltransferase (EC n/a
94 Q6U7R4_TLA Q6U7R4 T-cell immunoglobulin and n/a
95 Q89FH0_TLA Q89FH0 D(-)-tartrate dehydratase (EC n/a
96 Q9K0P4_TLA Q9K0P4 DNA mimic protein n/a
97 Q8CG76_TLA Q8CG76 Aflatoxin B1 aldehyde n/a
98 Q8XVB9_TLA Q8XVB9 Iron-binding zinc finger n/a
99 Q9HBE5_TLA Q9HBE5 Interleukin-21 receptor (IL-21 n/a
100 A1SZA3_TLA A1SZA3 3-dehydroquinate dehydratase (3-dehydroquinase) n/a
101 P53611_TLA P53611 Geranylgeranyl transferase type-2 n/a
102 Q83SB9_TLA Q83SB9 Enterochelin esterase n/a
103 Q99497_TLA Q99497 Parkinson disease protein n/a
104 P26196_TLA P26196 Probable ATP-dependent RNA n/a
105 P60757_TLA P60757 ATP phosphoribosyltransferase (ATP-PRT) n/a
106 Q9HXT9_TLA Q9HXT9 diguanylate cyclase (EC n/a
107 P54050_TLA P54050 Large ribosomal subunit n/a
108 O43175_TLA O43175 D-3-phosphoglycerate dehydrogenase (3-PGDH) n/a
109 Q8ZMG4_TLA Q8ZMG4 L-threonate dehydrogenase (EC n/a
110 Q8GRH0_TLA Q8GRH0 Beta-lactamase (EC 3.5.2.6) n/a
111 Q8PAE4_TLA Q8PAE4 Alpha/beta hydrolase n/a
112 O66440_TLA O66440 3-dehydroquinate dehydratase (3-dehydroquinase) n/a
113 Q9BQP7_TLA Q9BQP7 Mitochondrial genome maintenance n/a
114 E8T502_TLA E8T502 Carbonic anhydrase (EC n/a
115 T2D1F5_TLA T2D1F5 Glutamate dehydrogenase n/a
116 A0JYP2_TLA A0JYP2 Hydroxylase n/a
117 Q9DU47_TLA Q9DU47 Genome polyprotein n/a
118 P61769_TLA P61769 Beta-2-microglobulin [Cleaved into: n/a
119 P04585_TLA P04585 Gag-Pol polyprotein (Pr160Gag-Pol) n/a
120 Q70GK9_TLA Q70GK9 Fluorinase (EC 2.5.1.63) n/a
121 Q8E369_TLA Q8E369 Ribose-5-phosphate isomerase C-terminal n/a
122 Q7CSI0_TLA Q7CSI0 Isomerase/lactonizing enzyme n/a
123 Q9I4L4_TLA Q9I4L4 Negative regulator YfiR n/a
124 A7IKN6_TLA A7IKN6 Enoyl-CoA hydratase/isomerase n/a
125 Q9JJX7_TLA Q9JJX7 Tyrosyl-DNA phosphodiesterase 2 n/a
126 P08659_TLA P08659 Luciferin 4-monooxygenase (Luciferase) n/a
127 Q97NR6_TLA Q97NR6 deleted n/a
128 P54855_TLA P54855 UDP-glucuronosyltransferase 2B15 (UDPGT n/a
129 Q3T101_TLA Q3T101 IGL@ protein n/a
130 D0WGK0_TLA D0WGK0 Ketol-acid reductoisomerase (NADP(+)) n/a
131 Q5NWP0_TLA Q5NWP0 Uncharacterized protein n/a
132 Q8RVT0_TLA Q8RVT0 Thaumatin I (Thaumatin-1) n/a
133 P17597_TLA P17597 Acetolactate synthase, chloroplastic n/a
134 E6UTM3_TLA E6UTM3 deleted n/a
135 P42285_TLA P42285 Exosome RNA helicase n/a
136 P32169_TLA P32169 Rhamnulose-1-phosphate aldolase (EC n/a
137 P0ABE7_TLA P0ABE7 Soluble cytochrome b562 n/a
138 Q8A5V9_TLA Q8A5V9 Beta-phosphoglucomutase n/a
139 P26276_TLA P26276 Phosphomannomutase/phosphoglucomutase (PMM / n/a
140 P03950_TLA P03950 Angiogenin (EC 3.1.27.-) n/a
141 A0A0H2URQ6_TLA A0A0H2URQ6 Alpha-galactosidase (EC 3.2.1.22) n/a
142 B7MLA0_TLA B7MLA0 Enolase (EC 4.2.1.11) n/a
143 P47871_TLA P47871 Glucagon receptor (GL-R) n/a
144 Q9I5Q5_TLA Q9I5Q5 Anhydro-N-acetylmuramic acid kinase n/a
145 D0C9L6_TLA D0C9L6 Peptidyl-tRNA hydrolase (Pth) n/a
146 P35475_TLA P35475 Alpha-L-iduronidase (EC 3.2.1.76) n/a
147 O25927_TLA O25927 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (UDP-N-acetylglucosamine n/a
148 Q6L2R8_TLA Q6L2R8 Aspartate racemase (EC n/a
149 O66187_TLA O66187 Thiocyanate hydrolase subunit n/a
150 P45859_TLA P45859 Citrate/2-methylcitrate dehydratase (EC n/a
151 P80884_TLA P80884 Ananain (EC 3.4.22.31) n/a
152 P10366_TLA P10366 ATP phosphoribosyltransferase (ATP-PRT) n/a
153 Q86T24_TLA Q86T24 Transcriptional regulator Kaiso n/a
154 A3MU08_TLA A3MU08 6-phosphogluconate dehydrogenase, NAD-binding n/a
155 A1Z1Q3_TLA A1Z1Q3 ADP-ribose glycohydrolase MACROD2 n/a
156 E6Z0R3_TLA E6Z0R3 Protein adenylyltransferase VbhT n/a
157 D1GLU5_TLA D1GLU5 Non-ribosomal peptide synthetase n/a
158 D0C7F3_TLA D0C7F3 Chorismate synthase (CS) n/a
159 A0A8X6EH16_TLA A0A8X6EH16 Ketol-acid reductoisomerase (NADP(+)) n/a
160 Q9KVB4_TLA Q9KVB4 Capsular polysaccharide biosynthesis n/a
161 D4S0D1_TLA D4S0D1 3-dehydroquinate dehydratase (3-dehydroquinase) n/a
162 Q97L65_TLA Q97L65 Galactose mutarotase related n/a
163 Q2YQ74_TLA Q2YQ74 Beta-lactamase-like n/a
164 Q04771_TLA Q04771 Activin receptor type-1 n/a
165 G1UDU7_TLA G1UDU7 Putative monooxygenase (Reveromycin n/a
166 B7WQT1_TLA B7WQT1 Rieske (2Fe-2S) domain n/a
167 Q9FQF5_TLA Q9FQF5 Casein kinase II n/a
168 P08337_TLA P08337 8-oxo-dGTP diphosphatase (8-oxo-dGTPase) n/a
169 P51852_TLA P51852 Indole-3-pyruvate decarboxylase (Indolepyruvate n/a
170 P9WIL3_TLA P9WIL3 Aspartate 1-decarboxylase (EC n/a
171 V5VGT0_TLA V5VGT0 Aspartate-semialdehyde dehydrogenase (ASA n/a
172 A1IIJ1_TLA A1IIJ1 Thaumatin I (Thaumatin-1) n/a
173 P49792_TLA P49792 E3 SUMO-protein ligase n/a
174 Q9Y4U1_TLA Q9Y4U1 Cyanocobalamin reductase / n/a
175 P56817_TLA P56817 Beta-secretase 1 (EC n/a
176 P70731_TLA P70731 Nitrogen regulatory protein n/a
177 Q9APF7_TLA Q9APF7 Major acid phosphatase n/a
178 P44859_TLA P44859 Diaminopimelate epimerase (DAP n/a
179 P07954_TLA P07954 Fumarate hydratase, mitochondrial n/a
180 Q8YA39_TLA Q8YA39 Lmo0325 protein n/a
181 P42106_TLA P42106 Quercetin 2,3-dioxygenase (Quercetinase) n/a
182 P37432_TLA P37432 Outer membrane porin n/a
183 Q7Z144_TLA Q7Z144 MMACHC-like protein (EC n/a
184 Q15119_TLA Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] n/a
185 I9SUA3_TLA I9SUA3 Beta-galactosidase trimerisation domain-containing n/a
186 Q9GK12_TLA Q9GK12 Peptidoglycan recognition protein n/a
187 P15888_TLA P15888 Oxygen-insensitive NAD(P)H nitroreductase n/a
188 Q9HXQ8_TLA Q9HXQ8 Adenylate cyclase n/a
189 O60341_TLA O60341 Lysine-specific histone demethylase n/a
190 Q9ADP7_TLA Q9ADP7 HTH-type transcriptional repressor n/a
191 P47811_TLA P47811 Mitogen-activated protein kinase n/a
192 A0A485ICL5_TLA A0A485ICL5 deleted n/a
193 P0AA25_TLA P0AA25 Thioredoxin 1 (Trx-1) n/a
194 Q9HZ96_TLA Q9HZ96 Probable short-chain dehydrogenase n/a
195 P0C6Y1_TLA P0C6Y1 Replicase polyprotein 1ab n/a
196 Q63U92_TLA Q63U92 Aminotransferase (EC 2.6.1.-) n/a
197 P52895_TLA P52895 Aldo-keto reductase family n/a
198 Q9NZJ5_TLA Q9NZJ5 Eukaryotic translation initiation n/a
199 Q46925_TLA Q46925 Cysteine desulfurase CsdA n/a
200 Q2KDT2_TLA Q2KDT2 Probable hydroxyacid dehydrogenase n/a
201 P12271_TLA P12271 Retinaldehyde-binding protein 1 n/a
202 Q9NPH0_TLA Q9NPH0 Lysophosphatidic acid phosphatase n/a
203 P68175_TLA P68175 Strictosidine synthase (EC n/a
204 P0A544_TLA P0A544 D-3-phosphoglycerate dehydrogenase (PGDH) n/a
205 A0R5B5_TLA A0R5B5 glucarate dehydratase (EC n/a
206 P0A6K1_TLA P0A6K1 Diaminopimelate epimerase (DAP n/a
207 Q12657_TLA Q12657 Adenylyl-sulfate kinase (EC n/a
208 Q1LRY0_TLA Q1LRY0 Fused isobutyryl-CoA mutase n/a
209 Q2A612_TLA Q2A612 deleted n/a
210 Q5ZT65_TLA Q5ZT65 Ankyrin repeat domain n/a
211 Q9VGN3_TLA Q9VGN3 Peptidoglycan-recognition protein LB n/a
212 P15474_TLA P15474 3-dehydroquinate dehydratase (3-dehydroquinase) n/a
213 Q6PHZ2_TLA Q6PHZ2 Calcium/calmodulin-dependent protein kinase n/a
214 Q7M1Q1_TLA Q7M1Q1 Trypsin inhibitor BGIT n/a
215 P02883_TLA P02883 Thaumatin I (Thaumatin-1) n/a
216 F7BAY6_TLA F7BAY6 Albumin n/a
217 B7M7I1_TLA B7M7I1 4-hydroxy-tetrahydrodipicolinate synthase (HTPA n/a
218 P58154_TLA P58154 Acetylcholine-binding protein (ACh-binding n/a
219 B2JVW0_TLA B2JVW0 3-dehydroquinate dehydratase (3-dehydroquinase) n/a
220 G9I933_TLA G9I933 Alpha/beta fold hydrolase n/a
221 P0ADR6_TLA P0ADR6 Ribosomal RNA large n/a
222 P78417_TLA P78417 Glutathione S-transferase omega-1 n/a
223 P0AC84_TLA P0AC84 Hydroxyacylglutathione hydrolase GloB n/a
224 Q9I4Z7_TLA Q9I4Z7 Probable dna-binding stress n/a
225 B0RXY9_TLA B0RXY9 Tryptophan halogenase n/a
226 A0Q0N1_TLA A0Q0N1 Aluminum resistance protein n/a
227 P95028_TLA P95028 Rv2525c-like glycoside hydrolase-like n/a
228 Q4FQF7_TLA Q4FQF7 ATP phosphoribosyltransferase (ATP-PRT) n/a
229 Q14849_TLA Q14849 StAR-related lipid transfer n/a
230 G0L2Y1_TLA G0L2Y1 Alginate lyase, family n/a
231 O87605_TLA O87605 Cytochrome P450 monooxygenase n/a
232 P56073_TLA P56073 Shikimate kinase (SK) n/a
233 I7LG99_TLA I7LG99 RNA-directed DNA polymerase n/a
234 A0A1J4PXK4_TLA A0A1J4PXK4 Phytanoyl-CoA dioxygenase n/a
235 B7L0A5_TLA B7L0A5 Formate--tetrahydrofolate ligase (EC n/a
236 P53621_TLA P53621 Coatomer subunit alpha n/a
237 A0A384KFW3_TLA A0A384KFW3 Peptidoglycan D,D-transpeptidase MrdA n/a
238 Q9NP99_TLA Q9NP99 Triggering receptor expressed n/a
239 B4EEX4_TLA B4EEX4 Gluconate 5-dehydrogenase (EC n/a
240 P51449_TLA P51449 Nuclear receptor ROR-gamma n/a
241 Q7VU70_TLA Q7VU70 Conserved exported protein n/a
242 E2GHW2_TLA E2GHW2 GH26 endo-beta-1,4-mannanase (EC n/a
243 B4RIY7_TLA B4RIY7 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase n/a
244 P38207_TLA P38207 DNA-(apurinic or apyrimidinic n/a
245 I7FE16_TLA I7FE16 Isoniazid inducible gene n/a
246 Q8ZNF9_TLA Q8ZNF9 L-rhamnonate dehydratase (RhamD) n/a
247 A7M6E7_TLA A7M6E7 ToMV resistance protein n/a