Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: THYMIDINE-5'-PHOSPHATE
PDB ligand accession: TMP
DrugBank: DB01643
PubChem: 9700
ChEMBL: CHEMBL394429
InChI Key: GYOZYWVXFNDGLU-XLPZGREQSA-N
SMILES: CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)O)O

ClassyFire chemical classification:

List of proteins that are targets for TMP

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 C3W5S0_TMP C3W5S0 Polymerase acidic protein n/a
2 Q9C9G4_TMP Q9C9G4 Endonuclease 2 (AtENDO2) n/a
3 O67099_TMP O67099 Thymidylate kinase (EC n/a
4 B5L6K6_TMP B5L6K6 Methyltransferase n/a
5 Q9NPB1_TMP Q9NPB1 5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, n/a
6 P65248_TMP P65248 Thymidylate kinase (EC n/a
7 Q97RM2_TMP Q97RM2 deleted n/a
8 Q9D020_TMP Q9D020 Cytosolic 5'-nucleotidase 3A n/a
9 P04995_TMP P04995 Exodeoxyribonuclease I (ExoI) n/a
10 P0A884_TMP P0A884 Thymidylate synthase (TS) n/a
11 P37744_TMP P37744 Glucose-1-phosphate thymidylyltransferase 1 n/a
12 Q97W02_TMP Q97W02 DNA polymerase IV n/a
13 P03176_TMP P03176 Thymidine kinase (EC n/a
14 Q8I4S1_TMP Q8I4S1 Thymidylate kinase (PfTMK) n/a
15 Q9WYN2_TMP Q9WYN2 Thymidine kinase (EC n/a
16 Q91XB0_TMP Q91XB0 Three-prime repair exonuclease n/a
17 Q8KNF6_TMP Q8KNF6 CalS8 n/a
18 Q9R1E6_TMP Q9R1E6 Autotaxin (EC 3.1.4.39) n/a
19 O41078_TMP O41078 CMP/dCMP-type deaminase domain-containing n/a
20 A0A029ILG4_TMP A0A029ILG4 deleted n/a
21 Q59TV7_TMP Q59TV7 dTMP kinase (EC n/a
22 P00572_TMP P00572 Thymidylate kinase (EC n/a
23 P14565_TMP P14565 Multifunctional conjugation protein n/a
24 O13988_TMP O13988 Protection of telomeres n/a
25 Q7CWV1_TMP Q7CWV1 Protelomerase n/a
26 P08773_TMP P08773 Deoxycytidylate 5-hydroxymethyltransferase (Deoxycytidylate n/a
27 P76491_TMP P76491 5'-deoxynucleotidase YfbR (EC n/a
28 Q9RY51_TMP Q9RY51 Single-stranded DNA-binding protein n/a
29 A0A1P6BP23_TMP A0A1P6BP23 dTMP kinase (EC n/a
30 Q5SHX3_TMP Q5SHX3 Thymidylate kinase (EC n/a
31 P03007_TMP P03007 DNA polymerase III n/a
32 Q9Q0U9_TMP Q9Q0U9 Polymerase acidic protein n/a
33 Q746M7_TMP Q746M7 Protein argonaute (TtAgo) n/a
34 B3TMQ9_TMP B3TMQ9 Sugar 3-C-methyl transferase n/a
35 Q14527_TMP Q14527 Helicase-like transcription factor n/a
36 O52806_TMP O52806 PCZA361.16 n/a
37 O05891_TMP O05891 Thymidylate kinase (EC n/a
38 H6WFU3_TMP H6WFU3 Deoxycytidylate deaminase n/a
39 Q9HU22_TMP Q9HU22 Glucose-1-phosphate thymidylyltransferase (EC n/a
40 Q9KQI2_TMP Q9KQI2 Thymidylate kinase (EC n/a
41 Q9HZN8_TMP Q9HZN8 Thymidylate kinase (EC n/a
42 P00470_TMP P00470 Thymidylate synthase (TS) n/a
43 P23919_TMP P23919 Thymidylate kinase (EC product of
44 P06612_TMP P06612 DNA topoisomerase 1 n/a
45 D0EM60_TMP D0EM60 Single-stranded-DNA-specific exonuclease RecJ n/a
46 P00469_TMP P00469 Thymidylate synthase (TS) product of Ki(nM) = 8690.0
47 O57978_TMP O57978 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC n/a