Ligand name: [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate
PDB ligand accession: TOR
DrugBank: DB00273
PubChem: 5284627
ChEMBL: CHEMBL220492
InChI Key: KJADKKWYZYXHBB-XBWDGYHZSA-N
SMILES: CC1(OC2COC3(C(C2O1)OC(O3)(C)C)COS(=O)(=O)N)C

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Dioxolopyrans
      • Subclass: None

List of proteins that are targets for TOR

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	P14867_TOR	P14867	agonist
2	P00918_TOR	P00918	inhibitor	Ki(nM) = 5.0 IC50(nM) = 5.0 Kd(nM) = 13.8
3	P07451_TOR	P07451	inhibitor	Ki(nM) = 780000.0
4	Q15878_TOR	Q15878	antagonist
5	P00915_TOR	P00915	inhibitor	Ki(nM) = 56.0 IC50(nM) = 250.0
6	P22748_TOR	P22748	inhibitor	Ki(nM) = 4900.0