Ligand name: 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL
PDB ligand accession: TPF
DrugBank: DB00196
PubChem: 3365
ChEMBL: CHEMBL106
InChI Key: RFHAOTPXVQNOHP-UHFFFAOYSA-N
SMILES: c1cc(c(cc1F)F)C(Cn2cncn2)(Cn3cncn3)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Halobenzenes

List of proteins that are targets for TPF

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P14779_TPF	P14779	Bifunctional cytochrome P450/NADPH--P450	n/a
2	Q7Z1V1_TPF	Q7Z1V1	Sterol 14-alpha demethylase	n/a	IC50(nM) = 880.0 Kd(nM) = 230.0
3	A0A2H4A2U9_TPF	A0A2H4A2U9	CYP51, sterol 14alpha-demethylase	n/a
4	P0A514_TPF	P0A514	Mycocyclosin synthase (EC	n/a
5	Q385E8_TPF	Q385E8	Lanosterol 14-alpha-demethylase (EC	n/a
6	Q5I4E1_TPF	Q5I4E1	Sterol 14-alpha demethylase	n/a
7	A2TEF2_TPF	A2TEF2	Putative lanosterol 14-alpha-demethylase	n/a
8	P77901_TPF	P77901	Sterol 14alpha-demethylase (EC	n/a
9	P08684_TPF	P08684	Cytochrome P450 3A4	n/a	IC50(nM) = 8000.0
10	A6ZSR0_TPF	A6ZSR0	sterol 14alpha-demethylase (EC	n/a