Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: URIDINE-5'-MONOPHOSPHATE
PDB ligand accession: U5P
DrugBank: DB03685
PubChem: 6030
ChEMBL: CHEMBL214393
InChI Key: DJJCXFVJDGTHFX-XVFCMESISA-N
SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for U5P

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 O26745_U5P O26745 Putative snRNP Sm-like n/a
2 Q47VZ4_U5P Q47VZ4 Oligoribonuclease (EC 3.1.15.-) n/a
3 Q91XB0_U5P Q91XB0 Three-prime repair exonuclease n/a
4 Q9KQT7_U5P Q9KQT7 Orotidine 5'-phosphate decarboxylase n/a
5 Q6SA23_U5P Q6SA23 Nucleocapsid protein n/a
6 Q12149_U5P Q12149 Exosome complex exonuclease n/a
7 C3W5S0_U5P C3W5S0 Polymerase acidic protein n/a
8 Q9SVY5_U5P Q9SVY5 Serine/threonine-protein kinase ZRK1 n/a
9 P77398_U5P P77398 Bifunctional polymyxin resistance n/a
10 Q9NPB1_U5P Q9NPB1 5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, n/a
11 Q58830_U5P Q58830 Uncharacterized protein MJ1435 n/a
12 P0DTD1_U5P P0DTD1 Replicase polyprotein 1ab n/a
13 P42982_U5P P42982 N-acetyl-alpha-D-glucosaminyl L-malate synthase n/a
14 Q96662_U5P Q96662 Genome polyprotein [Cleaved n/a
15 P00441_U5P P00441 Superoxide dismutase [Cu-Zn] n/a
16 P09148_U5P P09148 Galactose-1-phosphate uridylyltransferase (Gal-1-P n/a
17 Q9V0Y8_U5P Q9V0Y8 Putative snRNP Sm-like n/a
18 Q9UKV8_U5P Q9UKV8 Protein argonaute-2 (Argonaute2) n/a
19 P00469_U5P P00469 Thymidylate synthase (TS) n/a
20 P0A1F6_U5P P0A1F6 Uridine phosphorylase (UPase) n/a
21 Q381M1_U5P Q381M1 Terminal uridylyltransferase 4 n/a
22 A9IH93_U5P A9IH93 Lipopolysaccharides biosynthesis acetyltransferase n/a
23 P27472_U5P P27472 Glycogen [starch] synthase n/a
24 P41007_U5P P41007 Bifunctional protein PyrR n/a
25 P11172_U5P P11172 Uridine 5'-monophosphate synthase n/a
26 O49839_U5P O49839 Probable serine/threonine-protein kinase n/a
27 Q38DE2_U5P Q38DE2 CCHC-type domain-containing protein n/a
28 P53078_U5P P53078 Suppressor of disruption n/a
29 Q7TG18_U5P Q7TG18 Genome polyprotein n/a
30 O04379_U5P O04379 Protein argonaute 1 n/a
31 P00968_U5P P00968 Carbamoyl phosphate synthase n/a
32 P08037_U5P P08037 Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase n/a
33 P70881_U5P P70881 Uracil phosphoribosyltransferase (EC n/a
34 Q96AZ6_U5P Q96AZ6 Interferon-stimulated gene 20 n/a
35 Q9HUM0_U5P Q9HUM0 RNA-binding protein Hfq n/a
36 Q9Q0U9_U5P Q9Q0U9 Polymerase acidic protein n/a
37 A0A178VJE3_U5P A0A178VJE3 aspartate carbamoyltransferase (EC n/a
38 H9CZL7_U5P H9CZL7 Ribonuclease J (RNase n/a
39 P0AA43_U5P P0AA43 Ribosomal small subunit n/a
40 Q8T6J6_U5P Q8T6J6 Orotidine 5'-phosphate decarboxylase n/a
41 P25971_U5P P25971 Orotidine 5'-phosphate decarboxylase n/a
42 Q9UXC0_U5P Q9UXC0 Exosome complex component n/a
43 P14769_U5P P14769 N-acetyllactosaminide alpha-1,3-galactosyltransferase (EC n/a
44 O58462_U5P O58462 Orotidine 5'-phosphate decarboxylase n/a
45 A0A0H3GNE4_U5P A0A0H3GNE4 Orotidine 5'-phosphate decarboxylase n/a
46 P0ABF6_U5P P0ABF6 Cytidine deaminase (EC n/a
47 O57978_U5P O57978 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC n/a
48 P23371_U5P P23371 Poly(A) polymerase catalytic n/a
49 Q48485_U5P Q48485 UDP-galactopyranose mutase (UGM) n/a
50 Q8U122_U5P Q8U122 Uridylate kinase (UK) n/a
51 Q980Q4_U5P Q980Q4 Uracil phosphoribosyltransferase (EC n/a
52 P49902_U5P P49902 Cytosolic purine 5'-nucleotidase n/a
53 P49773_U5P P49773 Adenosine 5'-monophosphoramidase HINT1 n/a
54 Q9WZI0_U5P Q9WZI0 Uracil phosphoribosyltransferase (EC n/a
55 C1IFD2_U5P C1IFD2 RNA-binding protein Hfq n/a
56 P0DX98_U5P P0DX98 Cyclic dipyrimidine nucleotide n/a
57 Q0QEE0_U5P Q0QEE0 Genome polyprotein n/a
58 P16442_U5P P16442 Histo-blood group ABO n/a
59 Q9BQ65_U5P Q9BQ65 U6 snRNA phosphodiesterase n/a
60 E9BCQ9_U5P E9BCQ9 Orotidine 5'-phosphate decarboxylase n/a
61 Q8B3M2_U5P Q8B3M2 Genome polyprotein [Cleaved n/a
62 L7N5T0_U5P L7N5T0 3'-5' exoribonuclease MT2234.1 n/a
63 P61823_U5P P61823 Ribonuclease pancreatic (EC n/a
64 O26232_U5P O26232 Orotidine 5'-phosphate decarboxylase n/a
65 P07617_U5P P07617 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase n/a
66 Q26998_U5P Q26998 Uracil phosphoribosyltransferase (UPRT) n/a
67 P23540_U5P P23540 Ribonuclease MC (RNase n/a
68 E7NKU1_U5P E7NKU1 deleted n/a
69 P03007_U5P P03007 DNA polymerase III n/a
70 Q70V26_U5P Q70V26 ABO glycosyltransferase n/a
71 Q5SLP1_U5P Q5SLP1 Ribonuclease TTHA0252 (EC n/a
72 W0TCJ5_U5P W0TCJ5 Uncharacterized protein YLR132C n/a
73 Q86MV5_U5P Q86MV5 Terminal uridylyltransferase 2 n/a
74 Q9UXC2_U5P Q9UXC2 Exosome complex component n/a
75 Q97ZE2_U5P Q97ZE2 Uridylate kinase (UK) n/a
76 Q9D020_U5P Q9D020 Cytosolic 5'-nucleotidase 3A n/a
77 P17574_U5P P17574 Coat protein n/a
78 P29464_U5P P29464 Uridylate kinase (UK) n/a
79 Q72JJ7_U5P Q72JJ7 Ribonuclease J (RNase n/a
80 A6UPF5_U5P A6UPF5 Putative snRNP Sm-like n/a
81 C4XAX5_U5P C4XAX5 deleted n/a