Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE
PDB ligand accession: UMP
DrugBank: DB03800
PubChem: 65063
ChEMBL: CHEMBL211312
InChI Key: JSRLJPSBLDHEIO-SHYZEUOFSA-N
SMILES: C1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)(O)O)O

ClassyFire chemical classification:

List of proteins that are targets for UMP

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 C3S7P8_UMP C3S7P8 Bifunctional dihydrofolate reductase-thymidylate n/a
2 Q77J90_UMP Q77J90 thymidylate synthase (EC n/a
3 C6GJB8_UMP C6GJB8 Thymidylate synthase (EC n/a
4 Q8NS38_UMP Q8NS38 Thymidylate synthase (TS) n/a
5 Q07422_UMP Q07422 Bifunctional dihydrofolate reductase-thymidylate n/a
6 P13922_UMP P13922 Bifunctional dihydrofolate reductase-thymidylate n/a
7 P04818_UMP P04818 Thymidylate synthase (TS) n/a Ki(nM) = 3000.0
8 P07607_UMP P07607 Thymidylate synthase (TS) n/a Ki(nM) = 6500.0
9 Q9ZDD2_UMP Q9ZDD2 Deoxyuridine 5'-triphosphate nucleotidohydrolase n/a
10 P15468_UMP P15468 Ribonuclease 4 (RNase n/a
11 P13100_UMP P13100 Thymidylate synthase (TS) n/a
12 Q27552_UMP Q27552 Bifunctional dihydrofolate reductase-thymidylate n/a
13 P0A552_UMP P0A552 Deoxyuridine 5'-triphosphate nucleotidohydrolase n/a
14 O43598_UMP O43598 5-hydroxymethyl-dUMP N-hydrolase (EC n/a
15 P00470_UMP P00470 Thymidylate synthase (TS) n/a
16 Q57ZH3_UMP Q57ZH3 Deoxyuridine triphosphatase, putative n/a
17 P67046_UMP P67046 Thymidylate synthase (TS) n/a
18 Q4JQW2_UMP Q4JQW2 Thymidylate synthase (TS) n/a
19 P27707_UMP P27707 Deoxycytidine kinase (dCK) n/a
20 O26061_UMP O26061 Flavin-dependent thymidylate synthase n/a
21 Q9NDD3_UMP Q9NDD3 Thymidylate synthase (EC n/a
22 Q8I1R6_UMP Q8I1R6 Bifunctional dihydrofolate reductase-thymidylate n/a
23 P0A886_UMP P0A886 Thymidylate synthase (TS) n/a
24 P06968_UMP P06968 Deoxyuridine 5'-triphosphate nucleotidohydrolase n/a
25 P0A884_UMP P0A884 Thymidylate synthase (TS) n/a
26 D9N170_UMP D9N170 Bifunctional dihydrofolate reductase-thymidylate n/a
27 Q9RS96_UMP Q9RS96 HAD superfamily Cof-like n/a
28 Q5CGA3_UMP Q5CGA3 deleted n/a
29 Q5ZSN0_UMP Q5ZSN0 Deoxyuridine 5'-triphosphate nucleotidohydrolase n/a
30 P11172_UMP P11172 Uridine 5'-monophosphate synthase n/a
31 P00469_UMP P00469 Thymidylate synthase (TS) n/a Ki(nM) = 2260.0
32 A4ZF98_UMP A4ZF98 dUTP diphosphatase (EC n/a
33 Q834R3_UMP Q834R3 Thymidylate synthase (TS) n/a
34 A7ASX7_UMP A7ASX7 Bifunctional dihydrofolate reductase-thymidylate n/a
35 Q9Y052_UMP Q9Y052 Thymidylate synthase (EC n/a
36 Q27793_UMP Q27793 Bifunctional dihydrofolate reductase-thymidylate n/a
37 O15826_UMP O15826 Putative deoxyuridine triphosphatase n/a
38 Q9WYT0_UMP Q9WYT0 Flavin-dependent thymidylate synthase n/a
39 F5HBQ9_UMP F5HBQ9 Thymidylate synthase (EC n/a
40 A7UD81_UMP A7UD81 Bifunctional dihydrofolate reductase-thymidylate n/a
41 O92810_UMP O92810 Gag-Pro polyprotein (Pr95) n/a
42 A0A4E9EZW9_UMP A0A4E9EZW9 Thymidylate synthase (EC n/a
43 Q9NPB1_UMP Q9NPB1 5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, n/a
44 A7UD79_UMP A7UD79 Bifunctional dihydrofolate reductase-thymidylate n/a
45 P03195_UMP P03195 Deoxyuridine 5'-triphosphate nucleotidohydrolase n/a
46 Q5UVJ4_UMP Q5UVJ4 Flavin-dependent thymidylate synthase n/a
47 P17374_UMP P17374 Deoxyuridine 5'-triphosphate nucleotidohydrolase n/a
48 A0A2X0SE53_UMP A0A2X0SE53 Deoxyuridine 5'-triphosphate nucleotidohydrolase n/a
49 Q9JM14_UMP Q9JM14 5'(3')-deoxyribonucleotidase, cytosolic type n/a
50 P16088_UMP P16088 Pol polyprotein [Cleaved n/a
51 P33317_UMP P33317 Deoxyuridine 5'-triphosphate nucleotidohydrolase n/a
52 O34919_UMP O34919 SPbeta prophage-derived deoxyuridine n/a
53 Q4DLS1_UMP Q4DLS1 Bifunctional dihydrofolate reductase-thymidylate n/a
54 P67044_UMP P67044 Thymidylate synthase (TS) n/a
55 P45352_UMP P45352 Thymidylate synthase (TS) n/a
56 P45351_UMP P45351 Thymidylate synthase (TS) n/a
57 A4JC15_UMP A4JC15 Glucose-1-phosphate thymidylyltransferase (EC n/a