Ligand name: UREA
PDB ligand accession: URE
DrugBank: DB03904
PubChem: 1176
ChEMBL: CHEMBL985
InChI Key: XSQUKJJJFZCRTK-UHFFFAOYSA-N
SMILES: C(=O)(N)N

ClassyFire chemical classification:

List of proteins that are targets for URE

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q0I663_URE Q0I663 Urea ABC transporter, n/a
2 Q2PBR5_URE Q2PBR5 Structural polyprotein n/a
3 O82825_URE O82825 HspA n/a
4 O75832_URE O75832 26S proteasome non-ATPase n/a
5 A0A4S5B4F2_URE A0A4S5B4F2 deleted n/a
6 B3U3M3_URE B3U3M3 Genome polyprotein n/a
7 Q9AM02_URE Q9AM02 C-phycocyanin alpha subunit n/a
8 Q9HYN5_URE Q9HYN5 Fucose-binding lectin PA-IIL n/a
9 Q8TQ92_URE Q8TQ92 ferredoxin:thioredoxin reductase (EC n/a
10 P17707_URE P17707 S-adenosylmethionine decarboxylase proenzyme n/a
11 P0ABQ4_URE P0ABQ4 Dihydrofolate reductase (EC n/a
12 P00698_URE P00698 Lysozyme C (EC n/a
13 P00800_URE P00800 Thermolysin (EC 3.4.24.27) n/a
14 P01903_URE P01903 HLA class II n/a
15 P0AEG4_URE P0AEG4 Thiol:disulfide interchange protein n/a
16 Q777D9_URE Q777D9 Uracil-DNA glycosylase (UDG) n/a
17 A0A0H3YL32_URE A0A0H3YL32 Urease subunit alpha n/a
18 P39138_URE P39138 Arginase (EC 3.5.3.1) n/a
19 P75682_URE P75682 Putative 2-dehydro-3-deoxy-D-gluconate aldolase n/a
20 Q6N0W2_URE Q6N0W2 Extracellular solute-binding protein n/a
21 P05091_URE P05091 Aldehyde dehydrogenase, mitochondrial n/a
22 P76342_URE P76342 Protein-methionine-sulfoxide reductase catalytic n/a
23 A0A0C4DFQ5_URE A0A0C4DFQ5 Kallikrein 4 (Prostase, n/a
24 P05089_URE P05089 Arginase-1 (EC 3.5.3.1) n/a
25 A0T1L9_URE A0T1L9 Moesin/ezrin/radixin homolog 1 n/a
26 P30464_URE P30464 HLA class I n/a
27 P00918_URE P00918 Carbonic anhydrase 2 n/a
28 P35222_URE P35222 Catenin beta-1 (Beta-catenin) n/a
29 P00523_URE P00523 Proto-oncogene tyrosine-protein kinase n/a
30 P05674_URE P05674 Structural polyprotein (p130) n/a
31 P00648_URE P00648 Ribonuclease (EC 3.1.27.-) n/a
32 B6JPK4_URE B6JPK4 Methyl-accepting chemotaxis transmembrane n/a
33 P61769_URE P61769 Beta-2-microglobulin [Cleaved into: n/a
34 P13760_URE P13760 HLA class II n/a
35 A7LBW5_URE A7LBW5 NblA n/a
36 P03367_URE P03367 Gag-Pol polyprotein (Pr160Gag-Pol) n/a
37 P0AC02_URE P0AC02 Outer membrane protein n/a
38 Q6CP22_URE Q6CP22 KLLA0E08119p n/a
39 P14739_URE P14739 Uracil-DNA glycosylase inhibitor n/a
40 P07824_URE P07824 Arginase-1 (EC 3.5.3.1) n/a
41 Q6VEQ7_URE Q6VEQ7 Kunitz-type inihibitor n/a
42 P02756_URE P02756 Beta-lactoglobulin (Beta-LG) n/a
43 Q02248_URE Q02248 Catenin beta-1 (Beta-catenin) n/a
44 P01308_URE P01308 Insulin [Cleaved into: n/a
45 G1EUI6_URE G1EUI6 Lectin n/a
46 Q71RW8_URE Q71RW8 C-phycocyanin beta subunit n/a
47 Q7U3J0_URE Q7U3J0 Putative urea ABC n/a
48 Q8YMJ3_URE Q8YMJ3 All4940 protein n/a
49 P30988_URE P30988 Calcitonin receptor (CT-R) n/a
50 Q46509_URE Q46509 Aldehyde oxidoreductase (EC n/a
51 Q5JIH3_URE Q5JIH3 Hydrogenase maturation factor n/a
52 P56817_URE P56817 Beta-secretase 1 (EC n/a
53 P03069_URE P03069 General control transcription n/a
54 P73600_URE P73600 Sll1785 protein n/a
55 Q6F6A2_URE Q6F6A2 Deoxyribodipyrimidine photo-lyase (EC n/a
56 P18771_URE P18771 Long-tail fiber proximal n/a
57 P02879_URE P02879 Ricin [Cleaved into: n/a