Ligand name: methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
PDB ligand accession: XIN
DrugBank: DB09079
PubChem: 9809715
ChEMBL: CHEMBL502835
InChI Key: XZXHXSATPCNXJR-ZIADKAODSA-N
SMILES: CN1CCN(CC1)CC(=O)N(C)c2ccc(cc2)NC(=C3c4ccc(cc4NC3=O)C(=O)OC)c5ccccc5

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Indoles and derivatives
      • Subclass: Indolecarboxylic acids and derivatives

List of proteins that are targets for XIN

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P22607_XIN	P22607	Fibroblast growth factor	inhibitor
2	P12931_XIN	P12931	Proto-oncogene tyrosine-protein kinase	inhibitor
3	P35968_XIN	P35968	Vascular endothelial growth	inhibitor
4	P11362_XIN	P11362	Fibroblast growth factor	inhibitor
5	Q14680_XIN	Q14680	Maternal embryonic leucine	n/a
6	P07948_XIN	P07948	Tyrosine-protein kinase Lyn	inhibitor
7	Q2M2I8_XIN	Q2M2I8	AP2-associated protein kinase	n/a
8	P17948_XIN	P17948	Vascular endothelial growth	inhibitor
9	P09619_XIN	P09619	Platelet-derived growth factor	inhibitor
10	P16234_XIN	P16234	Platelet-derived growth factor	inhibitor
11	P35916_XIN	P35916	Vascular endothelial growth	inhibitor
12	P36888_XIN	P36888	Receptor-type tyrosine-protein kinase	inhibitor
13	P06239_XIN	P06239	Tyrosine-protein kinase Lck	inhibitor
14	P07949_XIN	P07949	Proto-oncogene tyrosine-protein kinase	n/a
15	P21802_XIN	P21802	Fibroblast growth factor	inhibitor