PDB ligand accession: MTX
DrugBank: DB00563
PubChem:
ChEMBL:
InChI Key: FBOZXECLQNJBKD-ZDUSSCGKSA-N
SMILES: CN(Cc1cnc2c(n1)c(nc(n2)N)N)c3ccc(cc3)C(=O)NC(CCC(=O)O)C(=O)O
Drug action: n/a
ClassyFire chemical classification:
- Kingdom: Organic compounds
- Superclass: Organic acids and derivatives
- Class: Carboxylic acids and derivatives
- Subclass: Amino acids, peptides, and analogues
- Class: Carboxylic acids and derivatives
- Superclass: Organic acids and derivatives
| PDB/AF Accession | PyMOL script | Experimental / Predicted | Interacting ECOD domains | ECOD X-group name | LigPlot |
|---|---|---|---|---|---|
| 6PFI | Download | Experimental | e6pfiA2 e6pfiB2 e6pfiC1 e6pfiD1 e6pfiE1 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6OJS | Download | Experimental | e6ojsA2 e6ojsB2 e6ojsC2 e6ojsD1 e6ojsE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFD | Download | Experimental | e6pfdA1 e6pfdB1 e6pfdC2 e6pfdD1 e6pfdE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PF9 | Download | Experimental | e6pf9A2 e6pf9B2 e6pf9C2 e6pf9D1 e6pf9E2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFH | Download | Experimental | e6pfhA1 e6pfhB1 e6pfhC2 e6pfhD2 e6pfhE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFC | Download | Experimental | e6pfcA1 e6pfcB1 e6pfcC1 e6pfcD2 e6pfcE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6WEP | Download | Experimental | e6wepA2 e6wepB1 | Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFA | Download | Experimental | e6pfaA1 e6pfaB2 e6pfaC1 e6pfaD2 e6pfaE1 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFE | Download | Experimental | e6pfeA1 e6pfeB2 e6pfeC1 e6pfeD2 e6pfeE1 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PF8 | Download | Experimental | e6pf8A2 e6pf8B1 e6pf8C2 e6pf8D2 e6pf8E2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFF | Download | Experimental | e6pffA2 e6pffB1 e6pffC2 e6pffD1 e6pffE1 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PF7 | Download | Experimental | e6pf7A2 e6pf7B1 e6pf7C1 e6pf7D2 e6pf7E2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFG | Download | Experimental | e6pfgA1 e6pfgB1 e6pfgC2 e6pfgD2 e6pfgE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFB | Download | Experimental | e6pfbA2 e6pfbB2 e6pfbC1 e6pfbD1 e6pfbE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |