PDB ligand accession: NDP
DrugBank: DB02338
PubChem: 5884;134821689;
ChEMBL:
InChI Key: ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES: c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug action: n/a
ClassyFire chemical classification:
- Kingdom: Organic compounds
- Superclass: Nucleosides, nucleotides, and analogues
- Class: (5'->5')-dinucleotides
- Subclass: None
- Class: (5'->5')-dinucleotides
- Superclass: Nucleosides, nucleotides, and analogues
| PDB/AF Accession | PyMOL script | Experimental / Predicted | Interacting ECOD domains | ECOD X-group name | LigPlot |
|---|---|---|---|---|---|
| 6PFF | Download | Experimental | e6pffA2 e6pffB1 e6pffC2 e6pffD1 e6pffE1 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PF9 | Download | Experimental | e6pf9A2 e6pf9B2 e6pf9C2 e6pf9D1 e6pf9C1 e6pf9E2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Thymidylate synthase/dCMP hydroxymethylase Dihydrofolate reductases | LigPlot |
| 6PF8 | Download | Experimental | e6pf8A2 e6pf8B1 e6pf8C2 e6pf8D2 e6pf8E2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PF7 | Download | Experimental | e6pf7A2 e6pf7B1 e6pf7C1 e6pf7D2 e6pf7E2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFG | Download | Experimental | e6pfgA1 e6pfgB1 e6pfgB2 e6pfgC2 e6pfgD2 e6pfgE2 | Dihydrofolate reductases Dihydrofolate reductases Thymidylate synthase/dCMP hydroxymethylase Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFI | Download | Experimental | e6pfiA2 e6pfiB2 e6pfiC1 e6pfiD1 e6pfiE1 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFD | Download | Experimental | e6pfdA1 e6pfdB1 e6pfdC2 e6pfdD1 e6pfdE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFH | Download | Experimental | e6pfhA1 e6pfhB1 e6pfhD1 e6pfhC2 e6pfhD2 e6pfhE2 | Dihydrofolate reductases Dihydrofolate reductases Thymidylate synthase/dCMP hydroxymethylase Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6WEP | Download | Experimental | e6wepA2 e6wepB1 | Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFB | Download | Experimental | e6pfbA2 e6pfbB2 e6pfbC1 e6pfbD1 e6pfbE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6OJS | Download | Experimental | e6ojsA2 e6ojsB2 e6ojsC2 e6ojsD1 e6ojsE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFC | Download | Experimental | e6pfcA1 e6pfcB1 e6pfcC1 e6pfcD1 e6pfcD2 e6pfcE2 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Thymidylate synthase/dCMP hydroxymethylase Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFA | Download | Experimental | e6pfaA1 e6pfaB2 e6pfaC1 e6pfaD2 e6pfaE1 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |
| 6PFE | Download | Experimental | e6pfeA1 e6pfeB2 e6pfeC1 e6pfeD2 e6pfeE1 | Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases | LigPlot |