Ligand name: Fostamatinib
PDB ligand accession: 2RC
DrugBank: DB12010
InChI Key: GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Aniline and substituted anilines

List of PDB structures and/or AlphaFold models with target protein O00444

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
O00444	Download	Predicted	O00444_F1_nD2 O00444_F1_nD1	RIP/Polo-box domain Protein kinase/SAICAR synthase/ATP-grasp
2N19		Predicted	e2n19A1
3COK		Predicted	e3cokB1 e3cokA1
4JXF		Predicted	e4jxfA1
4N7V		Predicted	e4n7vA2 e4n7vB2 e4n7vA1 e4n7vB1
4N7Z		Predicted	e4n7zA2 e4n7zA1
4N9J		Predicted	e4n9jA2 e4n9jB2 e4n9jA1 e4n9jB1
4YUR		Predicted	e4yurA1
4YYP		Predicted	e4yypA1
5LHY		Predicted	e5lhyA1 e5lhyB1 e5lhyC1 e5lhyD1 e5lhyE1 e5lhyF1 e5lhyG1 e5lhyH1 e5lhyI1 e5lhyJ1 e5lhyK1 e5lhyL1 e5lhyM1 e5lhyN1 e5lhyO1 e5lhyP1 e5lhyQ1 e5lhyR1 e5lhyS1 e5lhyT1 e5lhyU1 e5lhyV1 e5lhyW1 e5lhyX1 e5lhyY1 e5lhyZ1 e5lhy11 e5lhy21 e5lhy31 e5lhy41 e5lhy51 e5lhy61 e5lhy71 e5lhy81 e5lhy91 e5lhya1 e5lhyb1 e5lhyc1 e5lhyd1 e5lhye1 e5lhyf1 e5lhyg1 e5lhyh1 e5lhyi1 e5lhyj1 e5lhyk1 e5lhyl1 e5lhym1 e5lhyn1 e5lhyo1 e5lhyp1 e5lhyq1 e5lhyr1 e5lhys1 e5lhyt1 e5lhyu1 e5lhyv1 e5lhyw1 e5lhyx1 e5lhyy1
5LHZ		Predicted	e5lhzA1 e5lhzB1 e5lhzC1
6N45		Predicted	e6n45A2 e6n45B1 e6n45A1 e6n45B2
6N46		Predicted	e6n46A1 e6n46B2 e6n46C1 e6n46D2 e6n46E1 e6n46F2 e6n46G2 e6n46H2 e6n46A2 e6n46B1 e6n46C2 e6n46D1 e6n46E2 e6n46F1 e6n46G1 e6n46H1