Ligand name: Fostamatinib
PDB ligand accession: 2RC
DrugBank: DB12010
InChI Key: GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Aniline and substituted anilines

List of PDB structures and/or AlphaFold models with target protein O43353

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
O43353	Download	Predicted	O43353_F1_nD1 O43353_F1_nD2	Protein kinase/SAICAR synthase/ATP-grasp DEATH domain
2N7Z		Predicted	e2n7zA1
2N83		Predicted	e2n83B1
4C8B		Predicted	e4c8bB2 e4c8bA2
5AR2		Predicted	e5ar2A1 e5ar2B1
5AR3		Predicted	e5ar3A1 e5ar3B1
5AR4		Predicted	e5ar4A1 e5ar4B1
5AR5		Predicted	e5ar5A1 e5ar5B1
5AR7		Predicted	e5ar7A1 e5ar7B1
5AR8		Predicted	e5ar8A1 e5ar8B1
5J79		Predicted	e5j79A1 e5j79B1
5J7B		Predicted	e5j7bA1 e5j7bB1
5NG0		Predicted	e5ng0A1 e5ng0B1
5NG2		Predicted	e5ng2A1 e5ng2B1
5NG3		Predicted	e5ng3D1 e5ng3B1 e5ng3C1 e5ng3A1
5W5J		Predicted	e5w5jA1 e5w5jB1
5W5O		Predicted	e5w5oA1 e5w5oB1 e5w5oC1 e5w5oD1 e5w5oE1 e5w5oF1 e5w5oG1 e5w5oH1 e5w5oI1 e5w5oJ1 e5w5oK1 e5w5oL1 e5w5oM1 e5w5oN1 e5w5oO1 e5w5oP1
5YRN		Predicted	e5yrnA1 e5yrnB1 e5yrnC1 e5yrnD1 e5yrnE1 e5yrnF1 e5yrnG1 e5yrnH1 e5yrnI1 e5yrnJ1 e5yrnK1 e5yrnL1
6ES0		Predicted	e6es0A1 e6es0B1
6FU5		Predicted	e6fu5A1 e6fu5B1
6GFJ		Predicted	e6gfjA3 e6gfjB3 e6gfjC3 e6gfjD3
6GGS		Predicted	e6ggsF1 e6ggsA1 e6ggsB1 e6ggsC1 e6ggsD1 e6ggsE1 e6ggsG1 e6ggsH1 e6ggsI1 e6ggsJ1
6HMX		Predicted	e6hmxA1 e6hmxB1
6RN8		Predicted	e6rn8A1 e6rn8B1
6RNA		Predicted	e6rnaB1 e6rnaA1
6S1F		Predicted	e6s1fA1 e6s1fD1 e6s1fB1 e6s1fC1
6SZE		Predicted	e6szeA1 e6szeB1
6SZJ		Predicted	e6szjA1 e6szjB1
6UL8		Predicted	e6ul8A1 e6ul8B1