Ligand name: N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine
PDB ligand accession: APJ
DrugBank: DB07382
InChI Key: WJNBSTLIALIIEW-UHFFFAOYSA-N
SMILES: c1cc2c(cc1Nc3nccc(n3)Nc4cc(n[nH]4)C5CC5)nc[nH]2
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Benzimidazoles
      • Subclass: None

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein O75460

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
O75460	Download	Predicted	O75460_F1_nD3	Protein kinase/SAICAR synthase/ATP-grasp
2HZ6		Predicted	e2hz6A1
3P23		Predicted	e3p23D2 e3p23B2 e3p23A2 e3p23C2 e3p23D1 e3p23B1 e3p23A1 e3p23C1
4U6R		Predicted	e4u6rA2 e4u6rA1
4YZ9		Predicted	e4yz9A2 e4yz9B2 e4yz9C1 e4yz9A1 e4yz9C2 e4yz9B1
4YZC		Predicted	e4yzcA1 e4yzcB2 e4yzcA2 e4yzcB1
4YZD		Predicted	e4yzdA2 e4yzdB1 e4yzdC1 e4yzdA1 e4yzdC2 e4yzdB2
4Z7G		Predicted	e4z7gA2 e4z7gB1 e4z7gB2 e4z7gA1
4Z7H		Predicted	e4z7hA1 e4z7hB1 e4z7hA2 e4z7hB2
5HGI		Predicted	e5hgiA2 e5hgiA1
6HV0		Predicted	e6hv0A2 e6hv0A1
6HX1		Predicted	e6hx1A1 e6hx1A2
6SHC		Predicted	e6shcA1
6URC		Predicted	e6urcA1 e6urcB1 e6urcA2 e6urcB2