Ligand name: 2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYLANILINO)METHYL]PYRIDO[2,3-D]PYRIMIDINE
PDB ligand accession: CO4
DrugBank: DB02104
PubChem: 447815
ChEMBL: CHEMBL50514
InChI Key: PEGMMEYCSOZKIT-UHFFFAOYSA-N
SMILES: Cc1c(cnc2c1c(nc(n2)N)N)CN(C)c3cc(c(c(c3)OC)OC)OC
Drug action: n/a

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyridopyrimidines
      • Subclass: Pyrido[2,3-d]pyrimidines

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein P00374

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name	LigPlot
1PD9	Download	Experimental	e1pd9A1	Dihydrofolate reductases	LigPlot
1PD8	Download	Experimental	e1pd8A1	Dihydrofolate reductases	LigPlot