Ligand name: 2,4-DIAMINO-6-[N-(3',4',5'-TRIMETHOXYBENZYL)-N-METHYLAMINO]PYRIDO[2,3-D]PYRIMIDINE
PDB ligand accession: DTM
DrugBank: DB02919
PubChem: 447229
ChEMBL: CHEMBL32190
InChI Key: PUOZHLHNKHRTOW-UHFFFAOYSA-N
SMILES: CN(Cc1cc(c(c(c1)OC)OC)OC)c2cc3c(nc(nc3nc2)N)N
Drug action: n/a

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyridopyrimidines
      • Subclass: Pyrido[2,3-d]pyrimidines

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein P00374

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name	LigPlot
1MVT	Download	Experimental	e1mvtA1	Dihydrofolate reductases	LigPlot
1MVS	Download	Experimental	e1mvsA1	Dihydrofolate reductases	LigPlot