Ligand name: (Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE
PDB ligand accession: LII
DrugBank: DB03060
PubChem: 446753
ChEMBL: n/a
InChI Key: WNDJHUNKXPAREB-PLNGDYQASA-N
SMILES: Cc1c(cnc2c1c(nc(n2)N)N)C=Cc3cc(ccc3OC)OC
Drug action: n/a

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyridopyrimidines
      • Subclass: Pyrido[2,3-d]pyrimidines

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein P00374

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name	LigPlot
1KMV	Download	Experimental	e1kmvA1	Dihydrofolate reductases	LigPlot