Ligand name: 6-(2,5-DIMETHOXY-BENZYL)-5-METHYL-PYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE
PDB ligand accession: MXA
DrugBank: DB03695
PubChem: 54369
ChEMBL: CHEMBL7492
InChI Key: VJXSSYDSOJBUAV-UHFFFAOYSA-N
SMILES: Cc1c(cnc2c1c(nc(n2)N)N)Cc3cc(ccc3OC)OC
Drug action: modulator

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyridopyrimidines
      • Subclass: Pyrido[2,3-d]pyrimidines

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein P00374

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name	LigPlot
1DLR	Download	Experimental	e1dlrA1	Dihydrofolate reductases	LigPlot
1U71	Download	Experimental	e1u71A1	Dihydrofolate reductases	LigPlot