Ligand name: 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
PDB ligand accession: N22
DrugBank: DB08234
InChI Key: NNFDQABYXZBKRK-UHFFFAOYSA-N
SMILES: CCc1c(c(nc(n1)N)N)C#CCc2cc(ccc2OC)OC
Drug action: n/a

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Methoxybenzenes

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein P00374

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
P00374	Download	Predicted	P00374_F1_nD1	Dihydrofolate reductases
1BOZ		Predicted	e1bozA1
1DHF		Predicted	e1dhfA1 e1dhfB1
1DLR		Predicted	e1dlrA1
1DLS		Predicted	e1dlsA1
1DRF		Predicted	e1drfA1
1HFP		Predicted	e1hfpA1
1HFQ		Predicted	e1hfqA1
1HFR		Predicted	e1hfrA1
1KMS		Predicted	e1kmsA1
1KMV		Predicted	e1kmvA1
1MVS		Predicted	e1mvsA1
1MVT		Predicted	e1mvtA1
1OHJ		Predicted	e1ohjA1
1OHK		Predicted	e1ohkA1
1PD8		Predicted	e1pd8A1
1PD9		Predicted	e1pd9A1
1PDB		Predicted	e1pdbA1
1S3U		Predicted	e1s3uA1
1S3V		Predicted	e1s3vA1
1S3W		Predicted	e1s3wA1
1U71		Predicted	e1u71A1
1U72		Predicted	e1u72A1
1YHO		Predicted	e1yhoA1
2C2S		Predicted	e2c2sA1 e2c2sB1
2C2T		Predicted	e2c2tB1 e2c2tA1
2DHF		Predicted	e2dhfB1 e2dhfA1
2W3A		Predicted	e2w3aA1 e2w3aB1
2W3B		Predicted	e2w3bA1 e2w3bB1
2W3M		Predicted	e2w3mA1 e2w3mB1
3EIG		Predicted	e3eigA1
3F8Y		Predicted	e3f8yA1
3F8Z		Predicted	e3f8zA1
3F91		Predicted	e3f91A1
3FS6		Predicted	e3fs6A1
3GHC		Predicted	e3ghcA1
3GHV		Predicted	e3ghvA1
3GHW		Predicted	e3ghwA1
3GI2		Predicted	e3gi2A1
3GYF		Predicted	e3gyfA1
3L3R		Predicted	e3l3rA1
3N0H		Predicted	e3n0hA1
3NTZ		Predicted	e3ntzA1
3NU0		Predicted	e3nu0A1
3NXO		Predicted	e3nxoA1
3NXR		Predicted	e3nxrA1
3NXT		Predicted	e3nxtA1
3NXV		Predicted	e3nxvA1
3NXX		Predicted	e3nxxA1
3NXY		Predicted	e3nxyA1
3NZD		Predicted	e3nzdA1
3OAF		Predicted	e3oafA1
3S3V		Predicted	e3s3vA1
3S7A		Predicted	e3s7aA1
4DDR		Predicted	e4ddrA1
4G95		Predicted	e4g95A1
4KAK		Predicted	e4kakA1 e4kakB1
4KBN		Predicted	e4kbnA1 e4kbnB1
4KD7		Predicted	e4kd7A1 e4kd7B1
4KEB		Predicted	e4kebA1 e4kebB1
4KFJ		Predicted	e4kfjA1 e4kfjB1
4M6J		Predicted	e4m6jA1
4M6K		Predicted	e4m6kA1
4M6L		Predicted	e4m6lA1
4QHV		Predicted	e4qhvA1
4QJC		Predicted	e4qjcA1
5HPB		Predicted	e5hpbA1
5HQY		Predicted	e5hqyA1
5HQZ		Predicted	e5hqzA1
5HSR		Predicted	e5hsrA1
5HSU		Predicted	e5hsuA1
5HT4		Predicted	e5ht4A1
5HT5		Predicted	e5ht5A1
5HUI		Predicted	e5huiA1
5HVB		Predicted	e5hvbA1
5HVE		Predicted	e5hveA1
6A7C		Predicted	e6a7cA1
6A7E		Predicted	e6a7eA1
6DAV		Predicted	e6davA1 e6davB1
6DE4		Predicted	e6de4A1 e6de4B1