Ligand name: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
PDB ligand accession: NAP
DrugBank: DB03461
PubChem: 5885;57525501;
ChEMBL: CHEMBL295069
InChI Key: XJLXINKUBYWONI-NNYOXOHSSA-N
SMILES: c1cc(c[n+](c1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)n4cnc5c4ncnc5N)OP(=O)(O)O)O)O)O)C(=O)N
Drug action: n/a

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Nucleosides, nucleotides, and analogues
    • Class: (5'->5')-dinucleotides
      • Subclass: None

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein P00374

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name	LigPlot
6DAV	Download	Experimental	e6davA1 e6davB1	Dihydrofolate reductases Dihydrofolate reductases	LigPlot
5SD8	Download	Experimental	e5sd8A1	Dihydrofolate reductases	LigPlot
5SD7	Download	Experimental	e5sd7A1	Dihydrofolate reductases	LigPlot
1S3W	Download	Experimental	e1s3wA1	Dihydrofolate reductases	LigPlot
6VCJ	Download	Experimental	e6vcjA1 e6vcjB1 e6vcjD1 e6vcjC1 e6vcjD1	Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases	LigPlot
4M6K	Download	Experimental	e4m6kA1	Dihydrofolate reductases	LigPlot
5SD9	Download	Experimental	e5sd9A1	Dihydrofolate reductases	LigPlot
7ESE	Download	Experimental	e7eseA1	Dihydrofolate reductases	LigPlot
5SD6	Download	Experimental	e5sd6A1	Dihydrofolate reductases	LigPlot
5SDB	Download	Experimental	e5sdbA1 e5sdbB1	Dihydrofolate reductases Dihydrofolate reductases	LigPlot
5SDA	Download	Experimental	e5sdaA1	Dihydrofolate reductases	LigPlot
4M6L	Download	Experimental	e4m6lA1	Dihydrofolate reductases	LigPlot