Ligand name: Spironolactone
PDB ligand accession: SNL
DrugBank: DB00421
InChI Key: LXMSZDCAJNLERA-ZHYRCANASA-N
SMILES: CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C
Drug action: antagonist

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Lipids and lipid-like molecules
    • Class: Steroids and steroid derivatives
      • Subclass: Steroid lactones

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein P04150

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
P04150	Download	Predicted	P04150_F1_nD2	Nuclear receptor ligand-binding domain
1M2Z		Predicted	e1m2zD1 e1m2zA1
1NHZ		Predicted	e1nhzA1
1P93		Predicted	e1p93C1 e1p93B1 e1p93D1 e1p93A1
3BQD		Predicted	e3bqdA1
3CLD		Predicted	e3cldA1 e3cldB1
3E7C		Predicted	e3e7cA1 e3e7cB1
3H52		Predicted	e3h52D1 e3h52C1 e3h52A1 e3h52B1
3K22		Predicted	e3k22A1 e3k22B1
3K23		Predicted	e3k23A1 e3k23B1 e3k23C1
4CSJ		Predicted	e4csjA1
4HN5		Predicted	e4hn5B1 e4hn5A2
4HN6		Predicted	e4hn6B2 e4hn6A2
4LSJ		Predicted	e4lsjA1
4MDD		Predicted	e4mddA1 e4mddB1
4P6W		Predicted	e4p6wA1
4P6X		Predicted	e4p6xA1 e4p6xC1 e4p6xE1 e4p6xG1 e4p6xI1 e4p6xK1
4UDC		Predicted	e4udcA1
4UDD		Predicted	e4uddA1
5CBX		Predicted	e5cbxB1 e5cbxE1 e5cbxF1 e5cbxA1
5CBY		Predicted	e5cbyA1 e5cbyB1
5CBZ		Predicted	e5cbzA1 e5cbzE1 e5cbzF1
5CC1		Predicted	e5cc1A1 e5cc1B1 e5cc1W1 e5cc1X1
5E69		Predicted	e5e69A1 e5e69B1
5E6A		Predicted	e5e6aA1 e5e6aB1
5E6B		Predicted	e5e6bB1 e5e6bA1
5E6C		Predicted	e5e6cA1 e5e6cB1
5E6D		Predicted	e5e6dA1 e5e6dB1
5EMC		Predicted	e5emcB1 e5emcA1
5EMP		Predicted	e5empA1 e5empB1
5EMQ		Predicted	e5emqB1 e5emqA1
5G3J		Predicted	e5g3jA1
5G5W		Predicted	e5g5wA1
5NFP		Predicted	e5nfpA1
5NFT		Predicted	e5nftA1
5UC3		Predicted	e5uc3A1 e5uc3B1
5VA0		Predicted	e5va0A1 e5va0B1
5VA7		Predicted	e5va7A1 e5va7B1
6BQU		Predicted	e6bquB1 e6bquA1
6CFN		Predicted	e6cfnC1 e6cfnB1 e6cfnF1 e6cfnG1 e6cfnH1 e6cfnA1 e6cfnD1 e6cfnE1
6DXK		Predicted	e6dxkB1 e6dxkA1
6EL6		Predicted	e6el6A1
6EL7		Predicted	e6el7A1
6EL9		Predicted	e6el9A1