Ligand name: Pralsetinib
PDB ligand accession: Q4J
DrugBank: DB15822
PubChem: n/a
ChEMBL: CHEMBL4297597
InChI Key: GBLBJPZSROAGMF-BATDWUPUSA-N
SMILES: Cc1cc(n[nH]1)Nc2cc(nc(n2)C3CCC(CC3)(C(=O)NC(C)c4ccc(nc4)n5cc(cn5)F)OC)C
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyridines and derivatives
      • Subclass: Pyrazolylpyridines

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein P07949

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name	LigPlot
7JU5	Download	Experimental	e7ju5A1 e7ju5A1 e7ju5B1	Protein kinase/SAICAR synthase/ATP-grasp Protein kinase/SAICAR synthase/ATP-grasp Protein kinase/SAICAR synthase/ATP-grasp	LigPlot
7DU9	Download	Experimental	e7du9B1 e7du9A1	Protein kinase/SAICAR synthase/ATP-grasp Protein kinase/SAICAR synthase/ATP-grasp	LigPlot