Ligand name: Ponatinib
PDB ligand accession: 0LI
DrugBank: DB08901
InChI Key: PHXJVRSECIGDHY-UHFFFAOYSA-N
SMILES: Cc1ccc(cc1C#Cc2cnc3n2nccc3)C(=O)Nc4ccc(c(c4)C(F)(F)F)CN5CCN(CC5)C
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Anilides

List of drug binding-associated PTMs

List of PDB structures and/or AlphaFold models with target protein P11362

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
P11362	Download	Predicted	P11362_F1_nD4	Protein kinase/SAICAR synthase/ATP-grasp
1AGW		Predicted	e1agwB1 e1agwA1
1CVS		Predicted	e1cvsC1 e1cvsD1 e1cvsD2 e1cvsC2
1EVT		Predicted	e1evtC1 e1evtD3 e1evtC3 e1evtD4
1FGI		Predicted	e1fgiA1 e1fgiB1
1FGK		Predicted	e1fgkA1 e1fgkB1
1FQ9		Predicted	e1fq9C1 e1fq9D1 e1fq9D2 e1fq9C2
2CR3		Predicted	e2cr3A1
2FGI		Predicted	e2fgiA1 e2fgiB1
3C4F		Predicted	e3c4fA1 e3c4fB1
3GQI		Predicted	e3gqiA1
3GQL		Predicted	e3gqlA1 e3gqlB1 e3gqlC1
3JS2		Predicted	e3js2B1 e3js2A1
3KXX		Predicted	e3kxxC1 e3kxxA1 e3kxxB1 e3kxxD2
3KY2		Predicted	e3ky2B1 e3ky2A1
3RHX		Predicted	e3rhxB1 e3rhxA1
3TT0		Predicted	e3tt0A1 e3tt0B1
4F63		Predicted	e4f63A1 e4f63B2
4F64		Predicted	e4f64B2 e4f64A2
4F65		Predicted	e4f65A2 e4f65B2
4NK9		Predicted	e4nk9A1 e4nk9B1
4NKA		Predicted	e4nkaB1 e4nkaA1
4NKS		Predicted	e4nksA1 e4nksB1
4RWI		Predicted	e4rwiA1 e4rwiB1
4RWJ		Predicted	e4rwjA1 e4rwjB1
4RWK		Predicted	e4rwkA1 e4rwkB1
4RWL		Predicted	e4rwlA1 e4rwlB1
4UWB		Predicted	e4uwbA1 e4uwbB1
4UWC		Predicted	e4uwcA1 e4uwcB1
4UWY		Predicted	e4uwyB1 e4uwyA1
4WUN		Predicted	e4wunA1 e4wunB1
4ZSA		Predicted	e4zsaA1 e4zsaB1
5A46		Predicted	e5a46A1 e5a46B1
5A4C		Predicted	e5a4cA1 e5a4cB1
5AM6		Predicted	e5am6B1 e5am6A1
5AM7		Predicted	e5am7A1 e5am7B1
5B7V		Predicted	e5b7vB1 e5b7vA1
5EW8		Predicted	e5ew8A1 e5ew8B1
5FLF		Predicted	e5flfB1 e5flfA1 e5flfC1 e5flfD1 e5flfE1
5O49		Predicted	e5o49B1 e5o49A1
5O4A		Predicted	e5o4aA1 e5o4aB1
5UQ0		Predicted	e5uq0A1 e5uq0B1
5UR1		Predicted	e5ur1A1 e5ur1B1
5VND		Predicted	e5vndB1 e5vndA1
5W21		Predicted	e5w21C1 e5w21C2
5W59		Predicted	e5w59B2 e5w59B1
5Z0S		Predicted	e5z0sA1 e5z0sB1
5ZV2		Predicted	e5zv2B1 e5zv2A1
6C18		Predicted	e6c18A1 e6c18B1
6C19		Predicted	e6c19A1 e6c19B1
6C1B		Predicted	e6c1bA1 e6c1bB1
6C1C		Predicted	e6c1cA1 e6c1cB1
6C1O		Predicted	e6c1oA1 e6c1oB1
6ITJ		Predicted	e6itjB1 e6itjA1
6MZQ		Predicted	e6mzqB1 e6mzqA1
6MZW		Predicted	e6mzwA1 e6mzwB1
6NVL		Predicted	e6nvlA1 e6nvlB1 e6nvlC1 e6nvlD1
6P68		Predicted	e6p68A1 e6p68B1 e6p68C1
6P69		Predicted	e6p69A1 e6p69B1