Ligand name: Fostamatinib
PDB ligand accession: 2RC
DrugBank: DB12010
InChI Key: GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Aniline and substituted anilines

List of PDB structures and/or AlphaFold models with target protein P48736

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
P48736	Download	Predicted	P48736_F1_nD3 P48736_F1_nD2 P48736_F1_nD4 P48736_F1_nD1	Repetitive alpha hairpins Immunoglobulin-like beta-sandwich Protein kinase/SAICAR synthase/ATP-grasp beta-Grasp
1E8Y		Predicted	e1e8yA6 e1e8yA3 e1e8yA5 e1e8yA4
1E8Z		Predicted	e1e8zA6 e1e8zA3 e1e8zA5 e1e8zA4
1HE8		Predicted	e1he8A3 e1he8A4 e1he8A2 e1he8A5
2A4Z		Predicted	e2a4zA2 e2a4zA5 e2a4zA3 e2a4zA4
2A5U		Predicted	e2a5uA6 e2a5uA5 e2a5uA3 e2a5uA4
2CHW		Predicted	e2chwA6 e2chwA5 e2chwA3 e2chwA4
2CHX		Predicted	e2chxA1 e2chxA3 e2chxA4 e2chxA2
2CHZ		Predicted	e2chzA5 e2chzA3 e2chzA1 e2chzA4
2V4L		Predicted	e2v4lA1 e2v4lA3 e2v4lA4 e2v4lA2
3APC		Predicted	e3apcA4 e3apcA1 e3apcA3 e3apcA2
3APD		Predicted	e3apdA2 e3apdA1 e3apdA3 e3apdA4
3APF		Predicted	e3apfA4 e3apfA2 e3apfA3 e3apfA1
3CSF		Predicted	e3csfA3 e3csfA4 e3csfA1 e3csfA2
3CST		Predicted	e3cstA5 e3cstA3 e3cstA2 e3cstA4
3DBS		Predicted	e3dbsA5 e3dbsA3 e3dbsA2 e3dbsA4
3DPD		Predicted	e3dpdA1 e3dpdA3 e3dpdA4 e3dpdA2
3ENE		Predicted	e3eneA1 e3eneA5 e3eneA2 e3eneA4
3IBE		Predicted	e3ibeA1 e3ibeA3 e3ibeA4 e3ibeA2
3L08		Predicted	e3l08A1 e3l08A3 e3l08A4 e3l08A2
3L13		Predicted	e3l13A5 e3l13A3 e3l13A1 e3l13A4
3L16		Predicted	e3l16A6 e3l16A5 e3l16A3 e3l16A4
3L17		Predicted	e3l17A6 e3l17A5 e3l17A3 e3l17A4
3L54		Predicted	e3l54A1 e3l54A3 e3l54A4 e3l54A2
3LJ3		Predicted	e3lj3A2 e3lj3A5 e3lj3A4 e3lj3A3
3MJW		Predicted	e3mjwA1 e3mjwA5 e3mjwA4 e3mjwA3
3ML8		Predicted	e3ml8A1 e3ml8A3 e3ml8A4 e3ml8A2
3ML9		Predicted	e3ml9A1 e3ml9A3 e3ml9A4 e3ml9A2
3NZS		Predicted	e3nzsA4 e3nzsA2 e3nzsA3 e3nzsA1
3NZU		Predicted	e3nzuA3 e3nzuA4 e3nzuA1 e3nzuA2
3OAW		Predicted	e3oawA1 e3oawA3 e3oawA4 e3oawA2
3P2B		Predicted	e3p2bA1 e3p2bA4 e3p2bA3 e3p2bA2
3PRE		Predicted	e3preA1 e3preA3 e3preA4 e3preA2
3PRZ		Predicted	e3przA1 e3przA3 e3przA4 e3przA2
3PS6		Predicted	e3ps6A1 e3ps6A3 e3ps6A4 e3ps6A2
3QAQ		Predicted	e3qaqA2 e3qaqA4 e3qaqA3 e3qaqA1
3QAR		Predicted	e3qarA4 e3qarA2 e3qarA3 e3qarA1
3QJZ		Predicted	e3qjzA4 e3qjzA2 e3qjzA3 e3qjzA1
3QK0		Predicted	e3qk0A6 e3qk0A2 e3qk0A5 e3qk0A1
3R7Q		Predicted	e3r7qA6 e3r7qA5 e3r7qA3 e3r7qA4
3R7R		Predicted	e3r7rA5 e3r7rA3 e3r7rA1 e3r7rA4
3S2A		Predicted	e3s2aA1 e3s2aA3 e3s2aA2 e3s2aA4
3SD5		Predicted	e3sd5A4 e3sd5A3 e3sd5A2 e3sd5A1
3T8M		Predicted	e3t8mA5 e3t8mA3 e3t8mA1 e3t8mA4
3TJP		Predicted	e3tjpA5 e3tjpA6 e3tjpA1 e3tjpA4
3TL5		Predicted	e3tl5A6 e3tl5A5 e3tl5A3 e3tl5A4
3ZVV		Predicted	e3zvvA5 e3zvvA3 e3zvvA2 e3zvvA4
3ZW3		Predicted	e3zw3A6 e3zw3A5 e3zw3A3 e3zw3A4
4ANU		Predicted	e4anuA2 e4anuA4 e4anuA1 e4anuA3
4ANV		Predicted	e4anvA1 e4anvA3 e4anvA4 e4anvA2
4ANW		Predicted	e4anwA3 e4anwA5 e4anwA4 e4anwA2
4ANX		Predicted	e4anxA4 e4anxA5 e4anxA1 e4anxA2
4AOF		Predicted	e4aofA4 e4aofA5 e4aofA1 e4aofA2
4DK5		Predicted	e4dk5A1 e4dk5A3 e4dk5A4 e4dk5A2
4EZJ		Predicted	e4ezjA2 e4ezjA5 e4ezjA1 e4ezjA4
4EZK		Predicted	e4ezkA4 e4ezkA5 e4ezkA1 e4ezkA3
4EZL		Predicted	e4ezlA4 e4ezlA2 e4ezlA3 e4ezlA1
4F1S		Predicted	e4f1sA4 e4f1sA2 e4f1sA3 e4f1sA1
4FA6		Predicted	e4fa6A1 e4fa6A5 e4fa6A2 e4fa6A4
4FAD		Predicted	e4fadA1 e4fadA3 e4fadA4 e4fadA2
4FHJ		Predicted	e4fhjA2 e4fhjA4 e4fhjA1 e4fhjA3
4FHK		Predicted	e4fhkA2 e4fhkA4 e4fhkA3 e4fhkA1
4FJY		Predicted	e4fjyA3 e4fjyA2 e4fjyA4 e4fjyA1
4FJZ		Predicted	e4fjzA4 e4fjzA2 e4fjzA3 e4fjzA1
4FLH		Predicted	e4flhA1 e4flhA3 e4flhA4 e4flhA2
4FUL		Predicted	e4fulA4 e4fulA2 e4fulA3 e4fulA1
4G11		Predicted	e4g11A4 e4g11A5 e4g11A1 e4g11A3
4GB9		Predicted	e4gb9A5 e4gb9A3 e4gb9A2 e4gb9A4
4HLE		Predicted	e4hleA4 e4hleA2 e4hleA3 e4hleA1
4HVB		Predicted	e4hvbA6 e4hvbA5 e4hvbA3 e4hvbA4
4J6I		Predicted	e4j6iA5 e4j6iA3 e4j6iA2 e4j6iA4
4KZ0		Predicted	e4kz0A2 e4kz0A4 e4kz0A3 e4kz0A1
4KZC		Predicted	e4kzcA2 e4kzcA4 e4kzcA1 e4kzcA3
4PS3		Predicted	e4ps3A3 e4ps3A6 e4ps3A5 e4ps3A4
4PS7		Predicted	e4ps7A5 e4ps7A6 e4ps7A1 e4ps7A4
4PS8		Predicted	e4ps8A5 e4ps8A6 e4ps8A3 e4ps8A4
4URK		Predicted	e4urkA2 e4urkA5 e4urkA1 e4urkA4
4WWN		Predicted	e4wwnA2 e4wwnA4 e4wwnA3 e4wwnA1
4WWO		Predicted	e4wwoA3 e4wwoA2 e4wwoA1 e4wwoA4
4WWP		Predicted	e4wwpA4 e4wwpA2 e4wwpA3 e4wwpA1
4XX5		Predicted	e4xx5A5 e4xx5A6 e4xx5A3 e4xx5A4
4XZ4		Predicted	e4xz4A2 e4xz4A5 e4xz4A1 e4xz4A4
5EDS		Predicted	e5edsA4 e5edsA2 e5edsA3 e5edsA1
5G2N		Predicted	e5g2nA1 e5g2nA5 e5g2nA3 e5g2nA4
5G55		Predicted	e5g55A3 e5g55A5 e5g55A4 e5g55A2
5JHA		Predicted	e5jhaA1 e5jhaA5 e5jhaA4 e5jhaA2
5JHB		Predicted	e5jhbA5 e5jhbA3 e5jhbA4 e5jhbA1
5KAE		Predicted	e5kaeA4 e5kaeA2 e5kaeA1 e5kaeA3
5OQ4		Predicted	e5oq4A3 e5oq4A5 e5oq4A1 e5oq4A4
5T23		Predicted	e5t23A2 e5t23A5 e5t23A4 e5t23A1
6AUD		Predicted	e6audA3 e6audA5 e6audA4 e6audA2
6C1S		Predicted	e6c1sA4 e6c1sA5 e6c1sA1 e6c1sA2
6FH5		Predicted	e6fh5A3 e6fh5A5 e6fh5A4 e6fh5A2
6GQ7		Predicted	e6gq7A2 e6gq7A5 e6gq7A4 e6gq7A1
6T3B		Predicted	e6t3bA2 e6t3bA3 e6t3bA1 e6t3bA4
6T3C		Predicted	e6t3cA2 e6t3cA4 e6t3cA3 e6t3cA1