Ligand name: Fostamatinib
PDB ligand accession: 2RC
DrugBank: DB12010
InChI Key: GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Aniline and substituted anilines

List of PDB structures and/or AlphaFold models with target protein Q05397

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
Q05397	Download	Predicted	Q05397_F1_nD5 Q05397_F1_nD4 Q05397_F1_nD2	Four-helical up-and-down bundle Protein kinase/SAICAR synthase/ATP-grasp Acyl-CoA binding protein-like
1K04		Predicted	e1k04A1
1K05		Predicted	e1k05A1 e1k05B1 e1k05C1
1MP8		Predicted	e1mp8A1
1OW6		Predicted	e1ow6A1 e1ow6B1 e1ow6C1
1OW7		Predicted	e1ow7A1 e1ow7B1 e1ow7C1
1OW8		Predicted	e1ow8A1 e1ow8B1 e1ow8C1
2ETM		Predicted	e2etmA1 e2etmB1
2IJM		Predicted	e2ijmA1 e2ijmB1
3B71		Predicted	e3b71A1 e3b71B1 e3b71C1
3BZ3		Predicted	e3bz3A1
3PXK		Predicted	e3pxkA1 e3pxkB1
3S9O		Predicted	e3s9oA1 e3s9oC1 e3s9oB1
4EBV		Predicted	e4ebvA1
4EBW		Predicted	e4ebwA1
4GU6		Predicted	e4gu6B1 e4gu6A1
4GU9		Predicted	e4gu9A1 e4gu9B1
4I4E		Predicted	e4i4eA1
4I4F		Predicted	e4i4fA1
4K8A		Predicted	e4k8aA1 e4k8aB1
4K9Y		Predicted	e4k9yA1
4KAB		Predicted	e4kabA1 e4kabB1
4KAO		Predicted	e4kaoA1 e4kaoB1
4NY0		Predicted	e4ny0C2 e4ny0A2 e4ny0B2 e4ny0D2 e4ny0D3 e4ny0A3 e4ny0B3 e4ny0C3 e4ny0A1 e4ny0B1 e4ny0C1 e4ny0D1
4Q9S		Predicted	e4q9sA1
6I8Z		Predicted	e6i8zA1
6LES		Predicted	e6lesY2 e6lesB1