Ligand name: Fostamatinib
PDB ligand accession: 2RC
DrugBank: DB12010
InChI Key: GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Aniline and substituted anilines

List of PDB structures and/or AlphaFold models with target protein Q14289

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
Q14289	Download	Predicted	Q14289_F1_nD1 Q14289_F1_nD2 Q14289_F1_nD5 Q14289_F1_nD4	beta-Grasp Acyl-CoA binding protein-like Four-helical up-and-down bundle Protein kinase/SAICAR synthase/ATP-grasp
2LK4		Predicted	e2lk4A1
3CC6		Predicted	e3cc6A1
3ET7		Predicted	e3et7A1
3FZO		Predicted	e3fzoA1
3FZP		Predicted	e3fzpA1
3FZR		Predicted	e3fzrA1
3FZS		Predicted	e3fzsA1
3FZT		Predicted	e3fztA1
3GM1		Predicted	e3gm1A1 e3gm1B1
3GM2		Predicted	e3gm2A1
3GM3		Predicted	e3gm3A1
3H3C		Predicted	e3h3cA1
3U3F		Predicted	e3u3fB1 e3u3fA1 e3u3fC1 e3u3fD1
4EKU		Predicted	e4ekuA4 e4ekuA1 e4ekuA3
4H1J		Predicted	e4h1jA1
4H1M		Predicted	e4h1mA2
4R32		Predicted	e4r32A1
4XEF		Predicted	e4xefA1 e4xefD1
4XEK		Predicted	e4xekA1
4XEV		Predicted	e4xevA1 e4xevD1
5TO8		Predicted	e5to8A1
5TOB		Predicted	e5tobA1