Ligand name: Fostamatinib
PDB ligand accession: 2RC
DrugBank: DB12010
InChI Key: GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Aniline and substituted anilines

List of PDB structures and/or AlphaFold models with target protein Q14680

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
Q14680	Download	Predicted	Q14680_F1_nD1 Q14680_F1_nD2	Protein kinase/SAICAR synthase/ATP-grasp TBP-like
4BKY		Predicted	e4bkyA2 e4bkyA1
4BKZ		Predicted	e4bkzA3 e4bkzA4
4BL1		Predicted	e4bl1A2 e4bl1A1
4D2P		Predicted	e4d2pA1 e4d2pB1 e4d2pD1 e4d2pC1 e4d2pA2 e4d2pB2 e4d2pD2 e4d2pC2
4D2T		Predicted	e4d2tA1 e4d2tC1 e4d2tB1 e4d2tD1 e4d2tA2 e4d2tC2 e4d2tB2 e4d2tD2
4D2V		Predicted	e4d2vC1 e4d2vA1 e4d2vB1 e4d2vD1 e4d2vA2 e4d2vC2 e4d2vB2 e4d2vD2
4D2W		Predicted	e4d2wA1 e4d2wB1 e4d2wC1 e4d2wD1 e4d2wA2 e4d2wB2 e4d2wC2 e4d2wD2
4IXP		Predicted	e4ixpA1 e4ixpA2
4UMP		Predicted	e4umpA1 e4umpB1 e4umpC1 e4umpD1 e4umpA2 e4umpB2 e4umpC2 e4umpD2
4UMQ		Predicted	e4umqA1 e4umqA2
4UMR		Predicted	e4umrA1 e4umrA2
4UMT		Predicted	e4umtA1 e4umtA2
4UMU		Predicted	e4umuA1 e4umuA2
5IH8		Predicted	e5ih8A1 e5ih8A2
5IH9		Predicted	e5ih9A2 e5ih9A1
5IHA		Predicted	e5ihaA2 e5ihaA1
5IHC		Predicted	e5ihcA2 e5ihcA1
5K00		Predicted	e5k00A1 e5k00A2
5M5A		Predicted	e5m5aA1 e5m5aA2
5MAF		Predicted	e5mafA1 e5mafA2
5MAG		Predicted	e5magA1 e5magA2
5MAH		Predicted	e5mahA2 e5mahA1
5MAI		Predicted	e5maiA2 e5maiA1
5TVT		Predicted	e5tvtA2 e5tvtA1
5TWL		Predicted	e5twlA1 e5twlA2
5TWU		Predicted	e5twuA1 e5twuB2 e5twuA2 e5twuB1
5TWY		Predicted	e5twyB2 e5twyA2 e5twyB1 e5twyA1
5TWZ		Predicted	e5twzA1 e5twzA2
5TX3		Predicted	e5tx3A2 e5tx3B2 e5tx3A1 e5tx3B1
6GVX		Predicted	e6gvxA1 e6gvxB2 e6gvxA2 e6gvxB1