Ligand name: Fostamatinib
PDB ligand accession: 2RC
DrugBank: DB12010
InChI Key: GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug action: inhibitor

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Aniline and substituted anilines

List of PDB structures and/or AlphaFold models with target protein Q15303

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name
Q15303	Download	Predicted	Q15303_F1_nD5 Q15303_F1_nD1 Q15303_F1_nD4 Q15303_F1_nD2 Q15303_F1_nD3	Protein kinase/SAICAR synthase/ATP-grasp Single-stranded right-handed beta-helix EGF-like EGF-like Single-stranded right-handed beta-helix
2AHX		Predicted	e2ahxA4 e2ahxB4 e2ahxA3 e2ahxB2 e2ahxA1 e2ahxB5 e2ahxA5 e2ahxB3
2R4B		Predicted	e2r4bA1 e2r4bB1
3BBT		Predicted	e3bbtB1 e3bbtD1
3BBW		Predicted	e3bbwA1 e3bbwB1
3BCE		Predicted	e3bceA1 e3bceB1 e3bceC1
3U2P		Predicted	e3u2pA1 e3u2pA2 e3u2pA3
3U7U		Predicted	e3u7uF1 e3u7uF2 e3u7uC4 e3u7uA4 e3u7uB4 e3u7uD4 e3u7uE4 e3u7uC3 e3u7uB3 e3u7uD3 e3u7uE3 e3u7uA1 e3u7uF3 e3u7uC1 e3u7uB1 e3u7uD5 e3u7uE2 e3u7uA3 e3u7uF4 e3u7uC2 e3u7uB5 e3u7uD2 e3u7uE5 e3u7uA2
3U9U		Predicted	e3u9uE1 e3u9uE2 e3u9uF2 e3u9uF5 e3u9uE4 e3u9uF3 e3u9uF4 e3u9uE3