Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: Fostamatinib
PDB ligand accession: 2RC
DrugBank: DB12010
InChI Key: GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug action: inhibitor

ClassyFire chemical classification:

List of PDB structures and/or AlphaFold models with target protein Q16539

PDB/AF Accession PyMOL script Experimental / Predicted Interacting ECOD domains ECOD X-group name
Q16539 Download Predicted Q16539_F1_nD1
 Protein kinase/SAICAR synthase/ATP-grasp
1A9U   Predicted e1a9uA1
  
1BL6   Predicted e1bl6A1
  
1BL7   Predicted e1bl7A1
  
1BMK   Predicted e1bmkA1
  
1DI9   Predicted e1di9A1
  
1IAN   Predicted e1ianA1
  
1KV1   Predicted e1kv1A1
  
1KV2   Predicted e1kv2A1
  
1M7Q   Predicted e1m7qA1
  
1OUK   Predicted e1oukA1
  
1OUY   Predicted e1ouyA1
  
1OVE   Predicted e1oveA1
  
1OZ1   Predicted e1oz1A1
  
1R39   Predicted e1r39A1
  
1R3C   Predicted e1r3cA1
  
1W7H   Predicted e1w7hA1
  
1W82   Predicted e1w82A1
  
1W83   Predicted e1w83A1
  
1W84   Predicted e1w84A1
  
1WBN   Predicted e1wbnA1
  
1WBO   Predicted e1wboA1
  
1WBS   Predicted e1wbsA1
  
1WBT   Predicted e1wbtA1
  
1WBV   Predicted e1wbvA1
  
1WBW   Predicted e1wbwA1
  
1WFC   Predicted e1wfcA1
  
1YQJ   Predicted e1yqjA1
  
1ZYJ   Predicted e1zyjA1
  
1ZZ2   Predicted e1zz2A1
  
1ZZL   Predicted e1zzlA1
  
2BAJ   Predicted e2bajA1
  
2BAK   Predicted e2bakA1
  
2BAL   Predicted e2balA1
  
2BAQ   Predicted e2baqA1
  
2FSL   Predicted e2fslX1
  
2FSM   Predicted e2fsmX1
  
2FSO   Predicted e2fsoX1
  
2FST   Predicted e2fstX1
  
2GFS   Predicted e2gfsA1
  
2I0H   Predicted e2i0hA1
  
2LGC   Predicted e2lgcA1
  
2NPQ   Predicted e2npqA1
  
2OKR   Predicted e2okrA1
e2okrD1
  
2ONL   Predicted e2onlB1
e2onlA1
  
2QD9   Predicted e2qd9A1
  
2RG5   Predicted e2rg5A1
  
2RG6   Predicted e2rg6A1
  
2Y8O   Predicted e2y8oA2
  
2YIS   Predicted e2yisA1
  
2YIW   Predicted e2yiwA1
  
2YIX   Predicted e2yixA1
  
2ZAZ   Predicted e2zazA1
  
2ZB0   Predicted e2zb0A1
  
2ZB1   Predicted e2zb1A1
  
3BV2   Predicted e3bv2A1
  
3BV3   Predicted e3bv3A1
  
3BX5   Predicted e3bx5A1
  
3C5U   Predicted e3c5uA1
  
3CTQ   Predicted e3ctqA1
  
3D7Z   Predicted e3d7zA1
  
3D83   Predicted e3d83A1
  
3DS6   Predicted e3ds6A1
e3ds6C1
e3ds6D1
e3ds6B1
  
3DT1   Predicted e3dt1A1
  
3E92   Predicted e3e92A1
  
3E93   Predicted e3e93A1
  
3FC1   Predicted e3fc1X1
  
3FI4   Predicted e3fi4A1
  
3FKL   Predicted e3fklA1
  
3FKN   Predicted e3fknA1
  
3FKO   Predicted e3fkoA1
  
3FL4   Predicted e3fl4A1
  
3FLN   Predicted e3flnC1
  
3FLQ   Predicted e3flqA1
  
3FLS   Predicted e3flsA1
  
3FLW   Predicted e3flwA1
  
3FLY   Predicted e3flyA1
  
3FLZ   Predicted e3flzA1
  
3FMH   Predicted e3fmhA1
  
3FMJ   Predicted e3fmjA1
  
3FMK   Predicted e3fmkA1
  
3FML   Predicted e3fmlA1
  
3FMM   Predicted e3fmmA1
  
3FMN   Predicted e3fmnA1
  
3FSF   Predicted e3fsfA1
  
3FSK   Predicted e3fskA1
  
3GC7   Predicted e3gc7A1
  
3GCP   Predicted e3gcpA1
  
3GCQ   Predicted e3gcqA1
  
3GCS   Predicted e3gcsA1
  
3GCU   Predicted e3gcuA1
e3gcuB1
  
3GCV   Predicted e3gcvA1
  
3GFE   Predicted e3gfeA1
  
3GI3   Predicted e3gi3A1
  
3HA8   Predicted e3ha8A1
  
3HEC   Predicted e3hecA1
  
3HEG   Predicted e3hegA1
  
3HL7   Predicted e3hl7A1
  
3HLL   Predicted e3hllA1
  
3HP2   Predicted e3hp2A1
  
3HP5   Predicted e3hp5A1
  
3HRB   Predicted e3hrbA1
  
3HUB   Predicted e3hubA1
  
3HUC   Predicted e3hucA1
  
3HV3   Predicted e3hv3A1
  
3HV4   Predicted e3hv4A1
e3hv4B1
  
3HV5   Predicted e3hv5A1
e3hv5B1
  
3HV6   Predicted e3hv6A1
  
3HV7   Predicted e3hv7A1
  
3HVC   Predicted e3hvcA1
  
3IPH   Predicted e3iphA1
  
3ITZ   Predicted e3itzA1
  
3IW5   Predicted e3iw5A1
  
3IW6   Predicted e3iw6A1
  
3IW7   Predicted e3iw7A1
  
3IW8   Predicted e3iw8A1
  
3K3I   Predicted e3k3iA1
  
3K3J   Predicted e3k3jA1
  
3KF7   Predicted e3kf7A1
  
3KQ7   Predicted e3kq7A1
  
3L8S   Predicted e3l8sA1
  
3L8X   Predicted e3l8xA1
  
3LFA   Predicted e3lfaA1
  
3LFB   Predicted e3lfbA1
  
3LFC   Predicted e3lfcA1
  
3LFD   Predicted e3lfdA1
  
3LFE   Predicted e3lfeA1
  
3LFF   Predicted e3lffA1
  
3LHJ   Predicted e3lhjA1
  
3MGY   Predicted e3mgyA1
  
3MH0   Predicted e3mh0A1
  
3MH1   Predicted e3mh1A1
  
3MH2   Predicted e3mh2A1
  
3MH3   Predicted e3mh3A1
  
3MPA   Predicted e3mpaA1
  
3MPT   Predicted e3mptA1
  
3MVL   Predicted e3mvlA1
e3mvlB1
  
3MVM   Predicted e3mvmA1
e3mvmB1
  
3MW1   Predicted e3mw1A1
  
3NEW   Predicted e3newA1
  
3NNU   Predicted e3nnuA1
  
3NNV   Predicted e3nnvA1
  
3NNW   Predicted e3nnwA1
  
3NNX   Predicted e3nnxA1
  
3NWW   Predicted e3nwwA1
  
3O8P   Predicted e3o8pA1
  
3O8T   Predicted e3o8tA1
  
3O8U   Predicted e3o8uA1
  
3OBG   Predicted e3obgA1
  
3OBJ   Predicted e3objA1
  
3OC1   Predicted e3oc1A1
  
3OCG   Predicted e3ocgA1
  
3OD6   Predicted e3od6X1
  
3ODY   Predicted e3odyX1
  
3ODZ   Predicted e3odzX1
  
3OEF   Predicted e3oefX1
  
3PG3   Predicted e3pg3A1
  
3QUD   Predicted e3qudA2
  
3QUE   Predicted e3queA2
  
3RIN   Predicted e3rinA2
  
3ROC   Predicted e3rocA1
  
3S3I   Predicted e3s3iA1
  
3S4Q   Predicted e3s4qA2
  
3U8W   Predicted e3u8wA2
  
3UVP   Predicted e3uvpA1
  
3UVQ   Predicted e3uvqA2
  
3UVR   Predicted e3uvrA1
  
3ZS5   Predicted e3zs5A2
  
3ZSG   Predicted e3zsgA2
  
3ZSH   Predicted e3zshA2
  
3ZSI   Predicted e3zsiA2
  
3ZYA   Predicted e3zyaA1
  
4A9Y   Predicted e4a9yA2
  
4AA0   Predicted e4aa0A2
  
4AA4   Predicted e4aa4A1
  
4AA5   Predicted e4aa5A1
  
4AAC   Predicted e4aacA1
  
4DLI   Predicted e4dliA2
  
4DLJ   Predicted e4dljA1
  
4E5A   Predicted e4e5aX1
  
4E5B   Predicted e4e5bA2
  
4E6A   Predicted e4e6aA2
  
4E6C   Predicted e4e6cA2
  
4E8A   Predicted e4e8aA2
  
4EH2   Predicted e4eh2A2
  
4EH3   Predicted e4eh3A1
  
4EH4   Predicted e4eh4A2
  
4EH5   Predicted e4eh5A2
  
4EH6   Predicted e4eh6A2
  
4EH7   Predicted e4eh7A2
  
4EH8   Predicted e4eh8A2
  
4EH9   Predicted e4eh9A2
  
4EHV   Predicted e4ehvA2
  
4EWQ   Predicted e4ewqA1
  
4F9W   Predicted e4f9wA2
  
4F9Y   Predicted e4f9yA2
  
4FA2   Predicted e4fa2A2
  
4GEO   Predicted e4geoA1
  
4KIN   Predicted e4kinD1
e4kinB1
e4kinC1
e4kinA1
  
4KIP   Predicted e4kipA1
e4kipB1
  
4KIQ   Predicted e4kiqA1
e4kiqB1
e4kiqC1
e4kiqD1
  
4L8M   Predicted e4l8mA1
  
4R3C   Predicted e4r3cA1
  
4ZTH   Predicted e4zthA1
  
5ETA   Predicted e5etaB1
e5etaA1
  
5ETC   Predicted e5etcA1
  
5ETF   Predicted e5etfA1
  
5ETI   Predicted e5etiA1
  
5ML5   Predicted e5ml5A1
  
5MTX   Predicted e5mtxA1
  
5MTY   Predicted e5mtyA1
  
5MZ3   Predicted e5mz3A1
  
5N63   Predicted e5n63A1
  
5N64   Predicted e5n64A1
  
5N65   Predicted e5n65A1
  
5N66   Predicted e5n66A1
  
5N67   Predicted e5n67A1
  
5N68   Predicted e5n68A1
  
5O8U   Predicted e5o8uA1
  
5O8V   Predicted e5o8vA1
  
5OMG   Predicted e5omgA1
  
5OMH   Predicted e5omhA1
  
5TBE   Predicted e5tbeA1
  
5TCO   Predicted e5tcoA1
  
5WJJ   Predicted e5wjjA1
  
5XYX   Predicted e5xyxA1
  
5XYY   Predicted e5xyyA1
  
6ANL   Predicted e6anlA1
  
6HWT   Predicted e6hwtA1
  
6HWU   Predicted e6hwuA1
  
6HWV   Predicted e6hwvA1
  
6M95   Predicted e6m95A1
  
6M9L   Predicted e6m9lA1
  
6OHD   Predicted e6ohdA1
  
6SFI   Predicted e6sfiA1
  
6SFJ   Predicted e6sfjA1
  
6SFK   Predicted e6sfkA1
  
6SFO   Predicted e6sfoA1