Ligand name: TRIMETHOPRIM
PDB ligand accession: TOP
DrugBank: DB00440
PubChem: 5578
ChEMBL: CHEMBL22
InChI Key: IEDVJHCEMCRBQM-UHFFFAOYSA-N
SMILES: COc1cc(cc(c1OC)OC)Cc2cnc(nc2N)N
Drug action: n/a

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Phenol ethers
      • Subclass: Anisoles

List of PDB structures and/or AlphaFold models with target protein Q81R22

PDB/AF Accession	PyMOL script	Experimental / Predicted	Interacting ECOD domains	ECOD X-group name	LigPlot
3JW3	Download	Experimental	e3jw3A1 e3jw3B1	Dihydrofolate reductases Dihydrofolate reductases	LigPlot
3JW5	Download	Experimental	e3jw5A1 e3jw5B1	Dihydrofolate reductases Dihydrofolate reductases	LigPlot
3FL9	Download	Experimental	e3fl9A1 e3fl9B1 e3fl9C1 e3fl9D1 e3fl9E1 e3fl9F1 e3fl9G1 e3fl9H1	Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases Dihydrofolate reductases	LigPlot