Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
A4TVL0 A4TVL0_9PROT
Gene name:
Protein name: Cereblon isoform 4

List of molecules and drugs that interact with protein A4TVL0

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 A4TVL0_7SE 7SE n/a 162678563 n/a (3S)-3-(benzotriazol-2-yl)piperidine-2,6-dione n/a
2 A4TVL0_835 835 n/a 24967954 n/a (3S)-3-(5-azanyl-2-methyl-4-oxidanylidene-quinazolin-3-yl)piperidine-2,6-dione n/a
3 A4TVL0_8W7 8W7 DB12101 67335295 CHEMBL3989927 (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione n/a
4 A4TVL0_9FT 9FT n/a 94767743 n/a (3R)-3-(4-methoxyphenyl)piperidine-2,6-dione n/a
5 A4TVL0_9UQ 9UQ n/a 86488 CHEMBL2051951 (3~{R})-3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione n/a
6 A4TVL0_9UT 9UT n/a n/a n/a 1,3-thiazole-2,4-dione n/a
7 A4TVL0_9UW 9UW n/a 23373589 n/a 2-sulfanylideneimidazol-4-one n/a
8 A4TVL0_9UZ 9UZ n/a 70726 CHEMBL3763941 piperidine-2,6-dione n/a
9 A4TVL0_9V2 9V2 n/a 10630591 n/a (3~{S})-3-ethyl-3-methyl-pyrrolidine-2,5-dione n/a
10 A4TVL0_ASP ASP DB00128 5960;44367445;139060126; CHEMBL274323 ASPARTIC ACID n/a
11 A4TVL0_BAQ BAQ DB19152 12025 CHEMBL276849 pyrrolidin-2-one n/a
12 A4TVL0_CA CA n/a 271 n/a CALCIUM ION n/a
13 A4TVL0_CL CL n/a 312 n/a CHLORIDE ION n/a
14 A4TVL0_DMS DMS DB01093 679 CHEMBL504 DIMETHYL SULFOXIDE n/a
15 A4TVL0_DUR DUR DB02256 13712 CHEMBL353955 2'-DEOXYURIDINE n/a
16 A4TVL0_EF2 EF2 n/a 92142 CHEMBL426123 S-Thalidomide n/a
17 A4TVL0_FLC FLC n/a 31348 n/a CITRATE ANION n/a
18 A4TVL0_HYN HYN n/a 10006 CHEMBL122334 imidazolidine-2,4-dione n/a
19 A4TVL0_JNW JNW n/a 134280 n/a 2-[[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]carbamoyl]benzoic acid n/a
20 A4TVL0_JO2 JO2 n/a 138756817 n/a 2-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyl]-4-nitro-benzoic acid n/a
21 A4TVL0_JO5 JO5 n/a 130431785 n/a 4-azanyl-2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]isoindole-1,3-dione n/a
22 A4TVL0_JO8 JO8 n/a 138756816 n/a 3-azanyl-2-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyl]benzoic acid n/a
23 A4TVL0_JOB JOB n/a 138756818 n/a 5-azanyl-2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]isoindole-1,3-dione n/a
24 A4TVL0_JOE JOE n/a 138756815 n/a 2-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyl]-6-nitro-benzoic acid n/a
25 A4TVL0_JOH JOH n/a 130431699 n/a 2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-4-nitro-isoindole-1,3-dione n/a
26 A4TVL0_JOK JOK n/a 138857409 n/a ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-3-phenyl-propanamide n/a
27 A4TVL0_JON JON n/a 138756822 n/a [(2~{S})-pyrrolidin-2-yl]methyl ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamate n/a
28 A4TVL0_JOQ JOQ n/a 138756821 n/a [4-(aminomethyl)phenyl]methyl ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamate n/a
29 A4TVL0_JOT JOT n/a 138756819 n/a ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-2-phenyl-ethanamide n/a
30 A4TVL0_JOW JOW n/a 138756824 n/a 4-[[4-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyloxymethyl]phenyl]methylamino]-4-oxidanylidene-butanoic acid n/a
31 A4TVL0_JP5 JP5 n/a 10083340 CHEMBL26221 (phenylmethyl) ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamate n/a
32 A4TVL0_JP8 JP8 n/a 138756823 n/a [(2~{R})-pyrrolidin-2-yl]methyl ~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]carbamate n/a
33 A4TVL0_JPB JPB n/a 138756825 n/a ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-2,4,6-tris(chloranyl)benzamide n/a
34 A4TVL0_JPQ JPQ n/a 138756827 n/a ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-3-methyl-but-2-enamide n/a
35 A4TVL0_JPW JPW n/a n/a n/a (4-azanylcyclohexyl)methyl ~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]carbamate n/a
36 A4TVL0_LVY LVY n/a 12044976 n/a S-Lenalidomide n/a
37 A4TVL0_MW6 MW6 n/a 166449448 n/a (3S)-3-[(3-aminophenyl)sulfanylmethyl]piperidine-2,6-dione n/a
38 A4TVL0_N8F N8F n/a 166449449 n/a (3~{S})-3-(phenylsulfonylmethyl)piperidine-2,6-dione n/a
39 A4TVL0_NI NI n/a 934 n/a NICKEL (II) ION n/a
40 A4TVL0_PO4 PO4 DB14523 1061 n/a PHOSPHATE ION n/a
41 A4TVL0_ROL ROL DB04149 448055 CHEMBL430893 ROLIPRAM n/a
42 A4TVL0_V1L V1L n/a 12665 CHEMBL12193 piperidin-2-one n/a
43 A4TVL0_W0Z W0Z n/a 169409276 n/a 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2,5-bis(fluoranyl)-3-methoxy-benzamide n/a
44 A4TVL0_W1B W1B n/a 169409275 n/a 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-oxidanyl-benzamide n/a
45 A4TVL0_W1F W1F n/a 169409274 n/a 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-methoxy-benzamide n/a
46 A4TVL0_W1T W1T n/a 155583991 n/a 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-fluoranyl-benzamide n/a
47 A4TVL0_W1X W1X n/a 169409272 n/a 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-(trifluoromethyl)benzamide n/a
48 A4TVL0_W26 W26 n/a 169409273 n/a 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-methyl-benzamide n/a
49 A4TVL0_W2F W2F n/a 169409271 n/a 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-chloranyl-benzamide n/a
50 A4TVL0_Y70 Y70 n/a 9965330 CHEMBL2093113 S-Pomalidomide n/a
51 A4TVL0_ZN ZN n/a 32051 CHEMBL1236970 ZINC ION n/a