Gene name:
Protein name: NS3 protease
List of molecules and drugs that interact with protein C1KIK8
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | C1KIK8_2R9 | 2R9 | DB11586 | 16076883 | CHEMBL2105735 | N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-L-prolinamide | n/a | |
| 2 | C1KIK8_5R2 | 5R2 | n/a | 105539866 | n/a | 2-Methyl-2-propanyl {(2R,6S,12Z,13aS,14aR,16aS)-14a-[(cyclopropylsulfonyl)carbamoyl]-2-[(3-ethyl-7-methoxy-2-quinoxalinyl)oxy]-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclop ropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl}carbamate | n/a | |
| 3 | C1KIK8_5RS | 5RS | n/a | 105539868 | n/a | ~{tert}-butyl ~{N}-[(2~{S})-1-[(2~{S},4~{R})-2-[[(1~{R},2~{R})-1-(cyclopropylsulfonylcarbamoyl)-2-ethyl-cyclopropyl]carbamoyl]-4-(3-ethyl-7-methoxy-quinoxalin-2-yl)oxy-pyrrolidin-1-yl]-3,3-dimethyl-1-oxidanylidene-butan-2-yl]carbamate | n/a | |
| 4 | C1KIK8_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 5 | C1KIK8_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 6 | C1KIK8_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 7 | C1KIK8_TSV | TSV | n/a | 49766491 | n/a | (2R,6S,12Z,13aS,14aR,16aS)-6-[(tert-butoxycarbonyl)amino]-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxo-1,2,3,5,6,7,8 ,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoro-2H-isoindole-2-carboxylate | n/a | |
| 8 | C1KIK8_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 9 | C1KIK8_SU3 | SU3 | DB11929 | 24765256 | CHEMBL4525964 | (5R,7S,10S)-10-tert-butyl-N-{(1R,2R)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethylcyclopropyl}-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19-dodecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosine-7(3H)-carboxamide | n/a | |
| 10 | C1KIK8_SUE | SUE | DB11575 | 44603531 | CHEMBL2063090 | (1aR,5S,8S,10R,22aR)-5-tert-butyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-14-methoxy-3,6-di oxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadec ino[11,12-b]quinoxaline-8-carboxamide | n/a |