Gene name: PA
Protein name: Polymerase acidic protein
List of molecules and drugs that interact with protein C3W5S0
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | C3W5S0_09Y | 09Y | n/a | 163359786 | n/a | 5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 2 | C3W5S0_0N8 | 0N8 | n/a | 6479291 | CHEMBL463590 | (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid | n/a | |
| 3 | C3W5S0_0VL | 0VL | n/a | 163359788 | n/a | benzyl {2-[(5S)-5-hydroxy-4-oxo-6-{[2-(pyridin-4-yl)ethyl]carbamoyl}-4,5-dihydropyrimidin-2-yl]propan-2-yl}carbamate | n/a | |
| 4 | C3W5S0_5Y1 | 5Y1 | n/a | 164575856 | n/a | (5R)-5-hydroxy-16,21-dioxa-3,8,28-triazatetracyclo[20.3.1.1~2,6~.1~11,15~]octacosa-1(26),2,6(28),11(27),12,14,22,24-octaene-4,7-dione | n/a | |
| 5 | C3W5S0_8KU | 8KU | n/a | 131953465;135567358; | n/a | 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-{[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 6 | C3W5S0_9HD | 9HD | n/a | 137348824 | n/a | 1-[(3R,5S,7R)-1,5,7,9-tetrakis(2-oxopyrrolidin-1-yl)nonan-3-yl]-1,3-dihydro-2H-pyrrol-2-one | n/a | |
| 7 | C3W5S0_9KU | 9KU | n/a | 131953461;135567354; | n/a | 5-hydroxy-2-[(2S)-1-{[(naphthalen-1-yl)oxy]acetyl}pyrrolidin-2-yl]-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid | n/a | |
| 8 | C3W5S0_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 9 | C3W5S0_CI1 | CI1 | n/a | 60147022 | n/a | (2Z)-4-[(3S)-1-(benzylsulfonyl)-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid | n/a | |
| 10 | C3W5S0_CI3 | CI3 | n/a | 60138153;72200823; | n/a | (2Z)-4-[(3S)-1-benzyl-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid | n/a | |
| 11 | C3W5S0_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 12 | C3W5S0_E4Z | E4Z | DB15675 | 124081876 | CHEMBL4297215 | Baloxavir acid | n/a | |
| 13 | C3W5S0_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 14 | C3W5S0_G1K | G1K | n/a | 131953464;135567357; | n/a | 5-hydroxy-6-oxo-2-[(2S)-1-(phenoxyacetyl)pyrrolidin-2-yl]-1,6-dihydropyrimidine-4-carboxylic acid | n/a | |
| 15 | C3W5S0_G2K | G2K | n/a | 131953463;135567356; | n/a | 2-{(2S)-1-[(2-chlorophenoxy)acetyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-N-(2-phenylethyl)-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 16 | C3W5S0_G3K | G3K | n/a | 131953466;135567359; | n/a | 2-{(2R)-1-[2-(4-chlorophenoxy)-2-methylpropanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid | n/a | |
| 17 | C3W5S0_G5V | G5V | n/a | 20463660 | CHEMBL1650617 | 5-hydroxy-2-methyl-4-oxo-4H-pyran-3-carboxylic acid | n/a | |
| 18 | C3W5S0_G5Y | G5Y | n/a | 3010943 | CHEMBL109448 | 3-hydroxy-4-oxo-4H-pyran-2-carboxylic acid | n/a | |
| 19 | C3W5S0_GK0 | GK0 | n/a | 137206697 | CHEMBL4086308 | 3,4,5-tris(oxidanyl)-~{N}-[(~{E})-[3,4,5-tris(oxidanyl)phenyl]methylideneamino]benzamide | n/a | |
| 20 | C3W5S0_GLU | GLU | DB00142 | 33032;44272391;88747398; | CHEMBL575060 | GLUTAMIC ACID | n/a | |
| 21 | C3W5S0_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 22 | C3W5S0_GY4 | GY4 | n/a | 131953462;135567355; | n/a | 2-{(2S)-1-[(4-chlorophenyl)acetyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid | n/a | |
| 23 | C3W5S0_GY5 | GY5 | n/a | 131953453;135567343; | n/a | 5-hydroxy-N-(2-methoxyethyl)-6-oxo-2-[(2S)-1-(phenoxyacetyl)pyrrolidin-2-yl]-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 24 | C3W5S0_GY6 | GY6 | n/a | 131953469;135567344; | n/a | 2-[(2S)-1-(2,6-dichlorobenzene-1-carbonyl)pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenylethyl)-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 25 | C3W5S0_GY7 | GY7 | n/a | 131953467;135567360; | n/a | 2-[(2S)-1-(2,6-difluorobenzene-1-carbonyl)pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenylethyl)-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 26 | C3W5S0_GY8 | GY8 | n/a | 131953456;135567346; | n/a | 2-[(2S)-1-(3,5-dichloropyridine-4-carbonyl)pyrrolidin-2-yl]-N-(2,3-dihydro-1H-inden-2-yl)-5-hydroxy-6-oxo-1,6-dihydropy rimidine-4-carboxamide | n/a | |
| 27 | C3W5S0_GY9 | GY9 | n/a | 131955126;135567345; | n/a | 2-{(2S)-1-[(2-chlorophenoxy)acetyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-N-(2-phenoxyethyl)-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 28 | C3W5S0_GYA | GYA | n/a | 131953460;135567353; | n/a | 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)-5-hydroxy-6-ox o-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 29 | C3W5S0_HJP | HJP | n/a | 83816179 | CHEMBL4173478 | 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid | n/a | |
| 30 | C3W5S0_HKD | HKD | n/a | 130407910 | CHEMBL4167809 | 4,6-dihydroxy-2-methyl-5-oxocyclohepta-1,3,6-triene-1-carboxylic acid | n/a | |
| 31 | C3W5S0_HNS | HNS | n/a | 130423218 | CHEMBL4545631 | 3-hydroxy-6-(2-methylphenyl)-4-oxo-1,4-dihydropyridine-2-carboxylic acid | n/a | |
| 32 | C3W5S0_HNY | HNY | n/a | 138455151 | CHEMBL4539596 | 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | n/a | |
| 33 | C3W5S0_HO1 | HO1 | n/a | 138455152 | CHEMBL4563716 | 3-hydroxy-4-oxo-6-[3-(1H-tetrazol-5-yl)phenyl]-1,4-dihydropyridine-2-carboxylic acid | n/a | |
| 34 | C3W5S0_HOG | HOG | n/a | 130423213 | CHEMBL4440338 | 6-(3-carboxyphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | n/a | |
| 35 | C3W5S0_HRJ | HRJ | n/a | 138455153 | CHEMBL4444029 | 3-hydroxy-6-[2-methyl-4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl]-4-oxo-1,4-dihydropyridine-2-carboxylic acid | n/a | |
| 36 | C3W5S0_HWA | HWA | n/a | 130423922 | CHEMBL4170746 | 3-hydroxy-6-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid | n/a | |
| 37 | C3W5S0_HWJ | HWJ | n/a | 138539163 | CHEMBL4555466 | 3-hydroxy-6-[2-methyl-4-(1H-tetrazol-5-yl)phenyl]-4-oxo-1,4-dihydropyridine-2-carboxylic acid | n/a | |
| 38 | C3W5S0_HWM | HWM | n/a | 130407971 | CHEMBL4531327 | 5-hydroxy-2-methyl-1-[4-(1H-tetrazol-5-yl)phenyl]pyridin-4(1H)-one | n/a | |
| 39 | C3W5S0_KDH | KDH | DB12116 | 65064 | CHEMBL297453 | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate | n/a | |
| 40 | C3W5S0_KU0 | KU0 | n/a | 131953471;135567348; | n/a | 2-[(2S)-1-(3,5-dichloropyridine-4-carbonyl)pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-[2-(phenylsulfonyl)ethyl]-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 41 | C3W5S0_KU2 | KU2 | n/a | 131953457;135567349; | n/a | 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenoxyethyl)-1,6-dihydropyrimidine-4 -carboxamide | n/a | |
| 42 | C3W5S0_KU4 | KU4 | n/a | 131953458;135567351; | n/a | 2-{(2S)-1-[3-(2-chlorophenyl)propanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-N-(2-phenoxyethyl)-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 43 | C3W5S0_KU5 | KU5 | n/a | 131953468;135567361; | n/a | 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-[2-(phenylsulfonyl)ethyl]-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 44 | C3W5S0_KU7 | KU7 | n/a | 133053971;135567350; | n/a | 2-{(2S)-1-[(2-fluorophenoxy)acetyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-N-(2-phenoxyethyl)-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 45 | C3W5S0_KU9 | KU9 | n/a | 131953459;135567352; | n/a | 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-(2,3-dihydro-1H-inden-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 46 | C3W5S0_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 47 | C3W5S0_MLT | MLT | DB03499 | 92824 | CHEMBL225986 | D-MALATE | n/a | |
| 48 | C3W5S0_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 49 | C3W5S0_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 50 | C3W5S0_PQO | PQO | n/a | 166175733 | CHEMBL5268084 | 6-bromo-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxamide | n/a | |
| 51 | C3W5S0_Q3O | Q3O | n/a | 54681553 | CHEMBL5282387 | 3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | n/a | |
| 52 | C3W5S0_QQ4 | QQ4 | n/a | 155289249 | n/a | Hexa Vinylpyrrolidone K15 | n/a | |
| 53 | C3W5S0_R07 | R07 | n/a | 68097023 | CHEMBL4103104 | 1-[(11S)-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-5-hydroxy-3-[(2R)-1,1,1-trifluoropropan-2-yl]-2,3-dihydro-1H-pyrido[2,1-f][1,2,4]triazine-4,6-dione | n/a | |
| 54 | C3W5S0_R1D | R1D | n/a | 155490979 | CHEMBL5400197 | 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-[2-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 55 | C3W5S0_R3J | R3J | n/a | 155804520 | n/a | benzyl [2-(5-hydroxy-4-{[2-(2-methoxypyridin-4-yl)ethyl]carbamoyl}-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl]carbamate | n/a | |
| 56 | C3W5S0_R6O | R6O | n/a | 144996594 | CHEMBL5289890 | 6-bromo-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carbonitrile | n/a | |
| 57 | C3W5S0_R6X | R6X | n/a | 90702473 | CHEMBL5289241 | 6-bromo-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | n/a | |
| 58 | C3W5S0_R7C | R7C | n/a | 137215902 | CHEMBL5278197 | (2M)-6-bromo-3-hydroxy-2-(1H-tetrazol-5-yl)pyridin-4(1H)-one | n/a | |
| 59 | C3W5S0_SL6 | SL6 | n/a | 6479654 | CHEMBL2040554 | (Z)-4-[4-[(4-chlorophenyl)methyl]-1-(cyclohexylmethyl)piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoic acid | n/a | |
| 60 | C3W5S0_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 61 | C3W5S0_TMP | TMP | DB01643 | 9700 | CHEMBL394429 | THYMIDINE-5'-PHOSPHATE | n/a | |
| 62 | C3W5S0_U5P | U5P | DB03685 | 6030 | CHEMBL214393 | URIDINE-5'-MONOPHOSPHATE | n/a | |
| 63 | C3W5S0_W5V | W5V | n/a | 156600261 | n/a | 2-(2,6-difluorophenyl)-5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-3,6-dihydropyrimidine-4-carboxamide | n/a | |
| 64 | C3W5S0_WTD | WTD | n/a | 156905830 | n/a | 2-(2,6-difluorophenyl)-5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-3,6-dihydropyrimidine-4-carboxamide | n/a | |
| 65 | C3W5S0_XI7 | XI7 | n/a | 493418 | CHEMBL19332 | 2-4-DIOXO-4-PHENYLBUTANOIC ACID | n/a | |
| 66 | C3W5S0_Y5V | Y5V | n/a | 162540421 | n/a | 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 67 | C3W5S0_ZHJ | ZHJ | n/a | 156620418 | n/a | 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-phenyl-1,6-dihydropyrimidine-4-carboxamide | n/a | |
| 68 | C3W5S0_T6U | T6U | n/a | 166175747 | CHEMBL5289714 | (2P)-6-bromo-3-hydroxy-2-(5-methyl-1,2,4-oxadiazol-3-yl)pyridin-4(1H)-one | n/a |