Gene name: blaNDM-1
Protein name: Metallo-beta-lactamase type 2
List of molecules and drugs that interact with protein C7C422
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | C7C422_0RM | 0RM | n/a | 54592403 | n/a | (2R,4S)-2-{(R)-carboxy[(2,6-dimethoxybenzoyl)amino]methyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | n/a | |
| 2 | C7C422_0RV | 0RV | n/a | 137347886 | n/a | (2S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-2H-pyrro le-5-carboxylic acid | n/a | |
| 3 | C7C422_0WO | 0WO | n/a | 26579868 | n/a | (2R,4S)-2-[(R)-carboxy{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carbo xylic acid | n/a | |
| 4 | C7C422_3C7 | 3C7 | n/a | 76936796 | CHEMBL4639950 | (3R,5R,7aS)-5-(sulfanylmethyl)tetrahydro[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid | n/a | |
| 5 | C7C422_3S0 | 3S0 | n/a | 86278043 | n/a | (2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | n/a | |
| 6 | C7C422_3S3 | 3S3 | n/a | 86278044 | n/a | (1R)-2-({(R)-carboxy[(2R,5S)-4-carboxy-5-methyl-5,6-dihydro-2H-1,3-thiazin-2-yl]methyl}amino)-2-oxo-1-phenylethanaminium | n/a | |
| 7 | C7C422_5ZX | 5ZX | n/a | 165901889 | n/a | 2-azanyl-5-(2-phenylethyl)-1,3-thiazole-4-carboxylic acid | n/a | |
| 8 | C7C422_7SX | 7SX | n/a | 130427308 | CHEMBL4576418 | [(5,7-dimethyl-2-oxo-1,2-dihydroquinolin-4-yl)methyl]phosphonic acid | n/a | |
| 9 | C7C422_8YL | 8YL | n/a | 10069633 | n/a | (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid | n/a | |
| 10 | C7C422_9DC | 9DC | n/a | 3246063 | n/a | (2S)-2,3-disulfanylpropan-1-ol | n/a | |
| 11 | C7C422_9DU | 9DU | n/a | 72947099 | CHEMBL3100077 | (2R)-2-methyl-N-(phenylmethyl)-3-sulfanyl-propanamide | n/a | |
| 12 | C7C422_9EX | 9EX | n/a | 59148462 | n/a | (2S)-2-methyl-3-sulfanyl-propan-1-ol | n/a | |
| 13 | C7C422_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 14 | C7C422_ACY | ACY | DB03166 | 176;21980959;160748163; | CHEMBL539 | ACETIC ACID | n/a | |
| 15 | C7C422_AU | AU | n/a | 114945 | n/a | GOLD ION | n/a | |
| 16 | C7C422_BME | BME | DB03345 | 1567 | CHEMBL254951 | BETA-MERCAPTOETHANOL | n/a | |
| 17 | C7C422_BS3 | BS3 | n/a | 5359367 | n/a | Bismuth(III) ION | n/a | |
| 18 | C7C422_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 19 | C7C422_CD | CD | n/a | 31193 | n/a | CADMIUM ION | n/a | |
| 20 | C7C422_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | inhibitor | |
| 21 | C7C422_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 22 | C7C422_CO | CO | n/a | 104729 | n/a | COBALT (II) ION | n/a | |
| 23 | C7C422_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 24 | C7C422_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 25 | C7C422_EEL | EEL | n/a | 93518054 | CHEMBL4784122 | (2R)-1-[3-sulfanyl-2-(sulfanylmethyl)propanoyl]pyrrolidine-2-carboxylic acid | n/a | |
| 26 | C7C422_EEO | EEO | n/a | 155289200 | CHEMBL4764694 | (2R)-1-[(2S)-2-methyl-3-sulfanyl-propanoyl]azepane-2-carboxylic acid | n/a | |
| 27 | C7C422_EER | EER | n/a | 93518314 | CHEMBL4779943 | (2R)-1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidine-2-carboxylic acid | n/a | |
| 28 | C7C422_EEX | EEX | n/a | 53767469 | CHEMBL4744333 | (1R)-2-[(2S)-2-methyl-3-sulfanyl-propanoyl]-3,4-dihydro-1H-isoquinoline-1-carboxylic acid | n/a | |
| 29 | C7C422_EF0 | EF0 | n/a | 155289204 | CHEMBL4792244 | 1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidine-4-carboxylic acid | n/a | |
| 30 | C7C422_EF9 | EF9 | n/a | 155289203 | CHEMBL4764352 | (3S)-1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidine-3-carboxylic acid | n/a | |
| 31 | C7C422_EFF | EFF | n/a | 155289205 | CHEMBL4759908 | 1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidine-4-carboxamide | n/a | |
| 32 | C7C422_EFR | EFR | n/a | 155289206 | CHEMBL4779672 | 2-[1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidin-4-yl]ethanamide | n/a | |
| 33 | C7C422_EG0 | EG0 | n/a | 155289207 | CHEMBL4793896 | 2-[1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidin-4-yl]ethanoic acid | n/a | |
| 34 | C7C422_EKX | EKX | n/a | 155804411 | n/a | (1S)-2-[(2S)-2-methyl-3-sulfanyl-propanoyl]-3,4-dihydro-1H-isoquinoline-1-carboxylic acid | n/a | |
| 35 | C7C422_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 36 | C7C422_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 37 | C7C422_FPM | FPM | DB12190 | 65894 | CHEMBL556262 | (5R,6S)-6-(1-hydroxyethyl)-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid | n/a | |
| 38 | C7C422_FUJ | FUJ | n/a | 326957 | CHEMBL4460704 | [(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 39 | C7C422_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 40 | C7C422_GTV | GTV | n/a | 29147132 | CHEMBL4545793 | [(5,7-dimethyl-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 41 | C7C422_H9E | H9E | n/a | 138320056 | n/a | [5-(bromomethyl)-1-benzothiophen-2-yl]-tris(oxidanyl)boranuide | n/a | |
| 42 | C7C422_HB8 | HB8 | n/a | 137797023 | n/a | [7-[(2-methylpropan-2-yl)oxycarbonylamino]-1-benzothiophen-2-yl]-tris(oxidanyl)boranuide | n/a | |
| 43 | C7C422_HCH | HCH | n/a | 137797037 | n/a | (7-carboxy-1-benzothiophen-2-yl)-tris(oxidanyl)boranuide | n/a | |
| 44 | C7C422_HCQ | HCQ | n/a | 137797036 | n/a | [5-(aminomethyl)-1-benzothiophen-2-yl]-tris(oxidanyl)boranuide | n/a | |
| 45 | C7C422_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 46 | C7C422_K9B | K9B | n/a | n/a | n/a | (4~{R})-4-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-3,3-bis(oxidanyl)-2-oxa-3-boranuidabicyclo[4.4.0]deca-1(10),6,8-triene-10-carboxylic acid | n/a | |
| 47 | C7C422_K9K | K9K | n/a | n/a | n/a | (10aR)-2-(((1r,4R)-4-((2-aminoethyl)amino)cyclohexyl)methyl)-6-carboxy-4-hydroxy-4,10a-dihydro-10H-benzo[5,6][1,2]oxaborinino[2,3-b][1,4,2]oxazaborol-4-uide | n/a | |
| 48 | C7C422_KED | KED | n/a | 130427306 | CHEMBL4553552 | [(2-oxo-1,2-dihydroquinolin-4-yl)methyl]phosphonic acid | n/a | |
| 49 | C7C422_M3Q | M3Q | n/a | 12629202 | CHEMBL4472640 | [(quinolin-8-yl)methyl]phosphonic acid | n/a | |
| 50 | C7C422_MCO | MCO | DB02032 | 447055 | CHEMBL434965 | 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID | n/a | |
| 51 | C7C422_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 52 | C7C422_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 53 | C7C422_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 54 | C7C422_N1G | N1G | n/a | 135379590 | CHEMBL5171499 | 1,5-diphenyl-N-(1H-tetrazol-5-yl)-1H-pyrazole-3-carboxamide | n/a | |
| 55 | C7C422_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 56 | C7C422_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 57 | C7C422_NPO | NPO | DB04417 | 980 | CHEMBL14130 | P-NITROPHENOL | n/a | |
| 58 | C7C422_O5E | O5E | n/a | 137796764 | n/a | (2R)-2-phenyl-2-(phenylamino)-N-(1H-tetrazol-5-yl)acetamide | n/a | |
| 59 | C7C422_OH | OH | DB14522 | 961 | n/a | HYDROXIDE ION | n/a | |
| 60 | C7C422_P6G | P6G | n/a | 17472 | CHEMBL1235082 | HEXAETHYLENE GLYCOL | n/a | |
| 61 | C7C422_P9T | P9T | n/a | 130427307 | CHEMBL4533674 | [(5,7-difluoro-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 62 | C7C422_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 63 | C7C422_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 64 | C7C422_PNK | PNK | n/a | n/a | CHEMBL1235368 | (2R,4S)-2-{(R)-carboxy[(phenylacetyl)amino]methyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | n/a | |
| 65 | C7C422_PNM | PNM | n/a | 5289182 | n/a | OPEN FORM - PENICILLIN G | n/a | |
| 66 | C7C422_QNA | QNA | n/a | 140830488 | n/a | (1~{a}~{R},7~{b}~{S})-5-fluoranyl-2,2-bis(oxidanyl)-1~{a},7~{b}-dihydro-1~{H}-cyclopropa[c][1,2]benzoxaborinine-4-carboxylic acid | n/a | |
| 67 | C7C422_QST | QST | n/a | 155295725 | CHEMBL5396807 | (2~{S},4~{S})-2-ethoxycarbonyl-5,5-dimethyl-2-(sulfanylmethyl)-1,3-thiazolidine-4-carboxylic acid | n/a | |
| 68 | C7C422_QT2 | QT2 | n/a | 155295724 | n/a | (2~{S},4~{R})-2-ethoxycarbonyl-5,5-dimethyl-2-(sulfanylmethyl)-1,3-thiazolidine-4-carboxylic acid | n/a | |
| 69 | C7C422_SCN | SCN | n/a | 9322 | n/a | THIOCYANATE ION | n/a | |
| 70 | C7C422_SFR | SFR | n/a | 23627205 | n/a | (2R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-5-[(2R)-oxolan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylic acid | n/a | |
| 71 | C7C422_SIN | SIN | DB00139 | 1110;21952380; | CHEMBL576 | SUCCINIC ACID | n/a | |
| 72 | C7C422_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 73 | C7C422_TOE | TOE | n/a | 8178 | CHEMBL1794613 | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL | n/a | |
| 74 | C7C422_TWB | TWB | n/a | 29148245 | CHEMBL4560587 | [(6,7-dimethyl-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 75 | C7C422_UNL | UNL | n/a | |||||
| 76 | C7C422_VKE | VKE | n/a | 39377739 | CHEMBL4539856 | [(6-oxo-2H,6H-[1,3]dioxolo[4,5-g][1]benzopyran-8-yl)methyl]phosphonic acid | n/a | |
| 77 | C7C422_WAF | WAF | n/a | 59585196 | CHEMBL3617543 | 1-hydroxy-6-sulfanylidene-1,6-dihydropyridine-2-carboxylic acid | n/a | |
| 78 | C7C422_WJZ | WJZ | n/a | 736152 | n/a | TIOPRONIN | n/a | |
| 79 | C7C422_X8Z | X8Z | DB01197 | 44093;12851888; | CHEMBL1560 | L-CAPTOPRIL | n/a | IC50(nM) = 49800.0 Kd(nM) = 14000.0 |
| 80 | C7C422_XJE | XJE | n/a | 130427415 | CHEMBL4553679 | [(5-methoxy-7-methyl-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 81 | C7C422_YKG | YKG | n/a | 130427303 | CHEMBL4519591 | [(5-bromo-7-methyl-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 82 | C7C422_YT4 | YT4 | n/a | 11391550 | n/a | methyl (2R)-2-(phenylmethoxycarbonylamino)-3-sulfanyl-propanoate | n/a | |
| 83 | C7C422_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 84 | C7C422_ZZ7 | ZZ7 | n/a | 6914605 | CHEMBL1237008 | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | n/a | |
| 85 | C7C422_SV7 | SV7 | n/a | 15295 | CHEMBL179801 | phenylphosphonic acid | n/a | |
| 86 | C7C422_T6Z | T6Z | n/a | 130427416 | CHEMBL4446363 | [(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)methyl]phosphonic acid | n/a |