Gene name: MEN1
Protein name: Menin
List of molecules and drugs that interact with protein O00255
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O00255_0BR | 0BR | n/a | 11859599 | CHEMBL531471 | (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol | n/a | |
| 2 | O00255_0RO | 0RO | n/a | 54765302 | CHEMBL3586089 | 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-d]pyrimidine | n/a | |
| 3 | O00255_0RT | 0RT | n/a | 72201086 | CHEMBL3586090 | 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine | n/a | |
| 4 | O00255_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 5 | O00255_2S6 | 2S6 | n/a | 49791890 | CHEMBL3126187 | 4-(3-{4-[(R)-cyclopentyl(hydroxy)phenylmethyl]piperidin-1-yl}propoxy)benzonitrile | n/a | |
| 6 | O00255_2S7 | 2S7 | n/a | n/a | CHEMBL3126201 | 4-(3-{4-[(S)-cyclopentyl(hydroxy)pyridin-2-ylmethyl]piperidin-1-yl}propoxy)benzonitrile | n/a | |
| 7 | O00255_2S9 | 2S9 | n/a | 73010397 | n/a | 4-(3-{4-[(R)-cyclopentyl(3-fluorophenyl)hydroxymethyl]piperidin-1-yl}propoxy)benzonitrile | n/a | |
| 8 | O00255_2SE | 2SE | n/a | 73010398 | n/a | 4-(3-{4-[(S)-cyclopentyl(hydroxy)pyridin-2-ylmethyl]piperidin-1-yl}propoxy)benzenesulfonamide | n/a | |
| 9 | O00255_2SF | 2SF | n/a | 71777747 | CHEMBL3126198 | 4-(3-{4-[(R)-amino(cyclopentyl)phenylmethyl]piperidin-1-yl}propoxy)benzonitrile | n/a | |
| 10 | O00255_2VK | 2VK | n/a | 49791889 | CHEMBL3124953 | 4-(3-{4-[(S)-cyclopentyl(hydroxy)phenylmethyl]piperidin-1-yl}propoxy)benzonitrile | n/a | |
| 11 | O00255_3XW | 3XW | n/a | 91667931 | CHEMBL3780822 | 4-methyl-1-(1H-pyrazol-4-ylmethyl)-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile | n/a | |
| 12 | O00255_3XY | 3XY | n/a | 86297077 | CHEMBL3780497 | 5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile | n/a | |
| 13 | O00255_58O | 58O | n/a | 90405035 | CHEMBL3780810 | 6-methoxy-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile | n/a | |
| 14 | O00255_58P | 58P | n/a | 90453223 | CHEMBL3780221 | 1-[(2S)-2,3-dihydroxypropyl]-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1 H-indole-2-carbonitrile | n/a | |
| 15 | O00255_58Q | 58Q | n/a | 117636649 | CHEMBL3781211 | 6-methoxy-4-methyl-1-(1H-pyrazol-4-ylmethyl)-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile | n/a | |
| 16 | O00255_58R | 58R | n/a | 90404695 | CHEMBL3781863 | 2-{2-cyano-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indol-1-yl}aceta mide | n/a | |
| 17 | O00255_59K | 59K | n/a | 90453086 | CHEMBL3612085 | 4-[4-(5-methyl-1,3,4-thiadiazol-2-yl)piperazin-1-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine | n/a | |
| 18 | O00255_59M | 59M | n/a | 86297674 | CHEMBL3613785 | 4-{4-[5-(fluoromethyl)-1,3,4-thiadiazol-2-yl]piperazin-1-yl}-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine | n/a | |
| 19 | O00255_59Q | 59Q | n/a | 86297462 | CHEMBL3613786 | 4-{4-[5-(difluoromethyl)-1,3,4-thiadiazol-2-yl]piperazin-1-yl}-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine | n/a | |
| 20 | O00255_59V | 59V | n/a | 86297465 | CHEMBL3613784 | 6-(2,2,2-trifluoroethyl)-4-{4-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperazin-1-yl}thieno[2,3-d]pyrimidine | n/a | |
| 21 | O00255_59X | 59X | n/a | 91864570 | CHEMBL3613788 | 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-(2-fluoroethyl)thieno[2,3-d]pyrimidine | n/a | |
| 22 | O00255_5A0 | 5A0 | n/a | 122189305 | CHEMBL3613789 | 6-(2,2-difluoroethyl)-4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]thieno[2,3-d]pyrimidine | n/a | |
| 23 | O00255_5A1 | 5A1 | n/a | 90453135 | CHEMBL3613790 | 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-(pentafluoroethyl)thieno[2,3-d]pyrimidine | n/a | |
| 24 | O00255_6E6 | 6E6 | n/a | 90453183 | CHEMBL3780415 | 1-[(2R)-2,3-dihydroxypropyl]-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile | n/a | |
| 25 | O00255_7IX | 7IX | n/a | 146636100 | CHEMBL5314517 | (1R,2S,4R)-4-[[4-(5,6-dimethoxypyridazin-3-yl)phenyl]methylamino]-2-[methyl-[6-[2,2,2-tris(fluoranyl)ethyl]thieno[2,3-d]pyrimidin-4-yl]amino]cyclopentan-1-ol | n/a | |
| 26 | O00255_7MM | 7MM | n/a | 146035889 | n/a | methyl [(1S,2R)-2-{(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-[1-({1-[4-({1-[4-(piperidin-1-yl)butanoyl]azetidin-3-yl}sulfonyl)phenyl]azetidin-3-yl}methyl)piperidin-4-yl]ethyl}cyclopentyl]carbamate | n/a | |
| 27 | O00255_7PR | 7PR | n/a | 165418;136496672; | n/a | praseodymium triacetate | n/a | |
| 28 | O00255_CHD | CHD | DB02659 | 221493 | CHEMBL205596 | CHOLIC ACID | n/a | |
| 29 | O00255_CJV | CJV | n/a | 137349101 | n/a | methyl {(1S,2R)-2-[(S)-cyano[1-({1-[4-({1-[4-(dimethylamino)butanoyl]azetidin-3-yl}sulfonyl)phenyl]azetidin-3-yl}methyl)piperidin-4-yl](3-fluorophenyl)methyl]cyclopentyl}carbamate | n/a | |
| 30 | O00255_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 31 | O00255_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 32 | O00255_EE7 | EE7 | n/a | 130375983 | CHEMBL4211318 | 1-{2-[4-(fluoroacetyl)piperazin-1-yl]ethyl}-4-methyl-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile | n/a | |
| 33 | O00255_EEV | EEV | n/a | 130376005 | CHEMBL4216801 | 4-methyl-1-{[(2S)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile | n/a | |
| 34 | O00255_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 35 | O00255_FNV | FNV | n/a | 130376007 | CHEMBL4210580 | 4-methyl-1-{[(2R)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile | n/a | |
| 36 | O00255_GGB | GGB | DB01833 | 439202;46224610; | CHEMBL443732 | L-CANAVANINE | n/a | |
| 37 | O00255_GLV | GLV | DB04343 | 760 | CHEMBL1162545 | GLYOXYLIC ACID | n/a | |
| 38 | O00255_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 39 | O00255_HL7 | HL7 | n/a | 138454904 | CHEMBL4449381 | (1S,2R)-2-[(4S)-2-methyl-4-{1-[(1-{4-[(pyridin-4-yl)sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}-1,2,3,4-tetrahydroisoquinolin-4-yl]cyclopentyl methylcarbamate | n/a | |
| 40 | O00255_LMY | LMY | n/a | n/a | n/a | ~{N}-[3-[[2-cyano-4-methyl-5-[[4-[[2-(methylamino)-6-[2,2,2-tris(fluoranyl)ethyl]thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indol-1-yl]methyl]-1-bicyclo[1.1.1]pentanyl]methanamide | n/a | |
| 41 | O00255_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 42 | O00255_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 43 | O00255_OP4 | OP4 | n/a | n/a | CHEMBL5267644 | 5-fluoro-2-({4-[7-({trans-4-[(methylsulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N,N-di(propan-2-yl)benzamide | n/a | |
| 44 | O00255_OQ4 | OQ4 | DB18515 | n/a | CHEMBL4650827 | 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide | n/a | |
| 45 | O00255_PE4 | PE4 | n/a | 448032 | n/a | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | n/a | |
| 46 | O00255_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 47 | O00255_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 48 | O00255_PGA | PGA | DB02726 | 529 | CHEMBL47181 | 2-PHOSPHOGLYCOLIC ACID | n/a | |
| 49 | O00255_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 50 | O00255_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 51 | O00255_TBF | TBF | DB02768 | 61207 | CHEMBL1236200 | TERT-BUTYL FORMATE | n/a | |
| 52 | O00255_UNX | UNX | n/a | |||||
| 53 | O00255_V6K | V6K | n/a | 1534213 | n/a | (~{E})-2-cyano-3-(4-hydroxyphenyl)-~{N}-(2-morpholin-4-ylethyl)prop-2-enamide | n/a | |
| 54 | O00255_YQV | YQV | n/a | 156587362 | CHEMBL5081163 | methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate | n/a |