Gene name: AURKA
Protein name: Aurora kinase A
List of molecules and drugs that interact with protein O14965
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O14965_0BX | 0BX | n/a | 56587958 | CHEMBL2170597 | 4-{[4-(phenylamino)pyrimidin-2-yl]amino}benzoic acid | n/a | |
| 2 | O14965_0BY | 0BY | n/a | 56587959 | CHEMBL2170601 | 4-({4-[(2-chlorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | n/a | |
| 3 | O14965_0BZ | 0BZ | n/a | 56587961 | CHEMBL2170427 | 4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | n/a | |
| 4 | O14965_0C0 | 0C0 | n/a | 56587962 | CHEMBL2170586 | 4-{[4-(biphenyl-2-ylamino)pyrimidin-2-yl]amino}benzoic acid | n/a | |
| 5 | O14965_0C3 | 0C3 | n/a | 56587963 | CHEMBL2170434 | 4-[(4-{[2-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid | n/a | |
| 6 | O14965_0C4 | 0C4 | n/a | 56587964 | CHEMBL2170435 | 4-({4-[(2-bromophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | n/a | |
| 7 | O14965_0C5 | 0C5 | n/a | 56587965 | CHEMBL2170440 | 4-({4-[(2-cyanophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | n/a | |
| 8 | O14965_0C6 | 0C6 | n/a | 56587966 | CHEMBL2170419 | 4-({4-[(2-chlorophenyl)amino]-5-fluoropyrimidin-2-yl}amino)benzoic acid | n/a | |
| 9 | O14965_0C7 | 0C7 | n/a | 56587967 | CHEMBL2170416 | N~4~-(2-chlorophenyl)-N~2~-[4-(1H-tetrazol-5-yl)phenyl]pyrimidine-2,4-diamine | n/a | |
| 10 | O14965_0C8 | 0C8 | n/a | 56587968 | CHEMBL2170430 | 4-[(4-{[2-(trifluoromethoxy)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid | n/a | |
| 11 | O14965_0C9 | 0C9 | n/a | 698343 | CHEMBL2170592 | 2-({2-[(4-carboxyphenyl)amino]pyrimidin-4-yl}amino)benzoic acid | n/a | |
| 12 | O14965_0FY | 0FY | n/a | n/a | n/a | 3-(1-{2-[(3-fluoropyridinium-4-yl)amino]-2-oxoethyl}-1H-pyrazol-4-yl)-6-methyl-8-[(3-{[(1R,3R)-3-methylpiperidinium-1-yl]methyl}-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-1-ium | n/a | |
| 13 | O14965_0K6 | 0K6 | n/a | 57383477 | CHEMBL2029903 | 7-cyclopentyl-2-({1-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-3-yl}amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide | n/a | |
| 14 | O14965_2JZ | 2JZ | n/a | 24767909 | CHEMBL1213151 | N~2~-(3,4-dimethoxyphenyl)-N~4~-[2-(2-fluorophenyl)ethyl]-N~6~-quinolin-6-yl-1,3,5-triazine-2,4,6-triamine | n/a | |
| 15 | O14965_2VU | 2VU | n/a | 71267243 | CHEMBL3263036 | N-[1-(3-cyanobenzyl)-1H-pyrazol-4-yl]-6-(1H-pyrazol-4-yl)-1H-indazole-3-carboxamide | n/a | |
| 16 | O14965_35R | 35R | DB05169 | 135398495 | CHEMBL495727 | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea | modulator | |
| 17 | O14965_400 | 400 | n/a | 11846878 | CHEMBL1230201 | 3-({[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]CARBONYL}AMINO)-N-[(1R)-1-PHENYLPROPYL]-1H-THIENO[3,2-C]PYRAZOLE-5-CARBOXAMIDE | n/a | |
| 18 | O14965_45B | 45B | n/a | 42628077 | CHEMBL508307 | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-N-(2-chlorophenyl)benzamide | n/a | |
| 19 | O14965_48B | 48B | n/a | 42628076 | CHEMBL523991 | 2-chloro-N-[4-({5-fluoro-2-[(4-hydroxyphenyl)amino]pyrimidin-4-yl}amino)phenyl]benzamide | n/a | |
| 20 | O14965_4QV | 4QV | n/a | 121231440 | CHEMBL3949078 | 5-hydroxy-1'H-1,2'-bibenzimidazol-2(3H)-one | n/a | |
| 21 | O14965_4RJ | 4RJ | n/a | n/a | CHEMBL3921246 | 6-({4-[(Z)-{(2Z)-2-[(4-ethylphenyl)imino]-3-methyl-4-oxo-1,3-thiazolidin-5-ylidene}methyl]pyridin-2-yl}amino)pyridine-3-carboxylic acid | n/a | |
| 22 | O14965_4RK | 4RK | n/a | n/a | CHEMBL3903187 | (2Z,5Z)-2-[(4-ethylphenyl)imino]-3-methyl-5-[(2-{[4-(1H-tetrazol-5-yl)phenyl]amino}pyridin-4-yl)methylidene]-1,3-thiazolidin-4-one | n/a | |
| 23 | O14965_4RM | 4RM | n/a | n/a | CHEMBL3941909 | (2Z,5Z)-2-[(4-ethylphenyl)imino]-3-(2-methoxyethyl)-5-(pyridin-4-ylmethylidene)-1,3-thiazolidin-4-one | n/a | |
| 24 | O14965_5DN | 5DN | n/a | 80043125 | n/a | 2-(3-bromophenyl)-8-fluoroquinoline-4-carboxylic acid | n/a | |
| 25 | O14965_5E1 | 5E1 | n/a | 673699 | n/a | 2-(3-bromophenyl)quinoline-4-carboxylic acid | n/a | |
| 26 | O14965_5E2 | 5E2 | n/a | 25218890 | n/a | 2-(3-bromophenyl)-6-chloroquinoline-4-carboxylic acid | n/a | |
| 27 | O14965_5GX | 5GX | n/a | 91844455 | n/a | 7-(1-benzyl-1H-pyrazol-4-yl)-6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine | n/a | |
| 28 | O14965_5VC | 5VC | DB12556 | n/a | CHEMBL3600873 | 4-(3-chloranyl-2-fluoranyl-phenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid | regulator | |
| 29 | O14965_5YZ | 5YZ | n/a | 163359790 | n/a | 6-[(5-cyclopropyl-1~{H}-pyrazol-3-yl)amino]-2-[4-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazin-1-yl]-~{N}-prop-2-ynyl-pyrimidine-4-carboxamide | n/a | |
| 30 | O14965_626 | 626 | DB07186 | 11963557 | n/a | 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE | n/a | |
| 31 | O14965_627 | 627 | DB11778 | 11442891 | CHEMBL402548 | N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE | inhibitor | |
| 32 | O14965_6F2 | 6F2 | n/a | 91844458 | n/a | [3-[[4-[6-chloranyl-2-(1,3-dimethylpyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl]pyrazol-1-yl]methyl]phenyl]-(4-methylpiperazin-1-yl)methanone | n/a | |
| 33 | O14965_7HD | 7HD | n/a | 91844456 | n/a | 3-((4-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)-1H-pyrazol-1-yl)methyl)-5-methylisoxazole | n/a | |
| 34 | O14965_83H | 83H | DB07266 | 135564980 | CHEMBL223147 | 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1H)-one | n/a | |
| 35 | O14965_97B | 97B | n/a | 11656967 | n/a | 9-chloro-7-(2,6-difluorophenyl)-N-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5H-pyrimido[5,4-d][2]benzazepin-2-amine | n/a | |
| 36 | O14965_9A6 | 9A6 | n/a | 137331508 | n/a | 7-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]quinazolin-4-amine | n/a | |
| 37 | O14965_9QK | 9QK | n/a | 28365719 | n/a | 2-(3-fluorophenyl)quinoline-4-carboxylic acid | n/a | |
| 38 | O14965_9QT | 9QT | n/a | 129316478 | n/a | 2-(3-chloranyl-5-fluoranyl-phenyl)quinoline-4-carboxylic acid | n/a | |
| 39 | O14965_9YQ | 9YQ | n/a | 129900111 | CHEMBL4206831 | 4-(propanoylamino)-~{N}-[4-[(5,8,11-trimethyl-6-oxidanylidene-pyrimido[4,5-b][1,4]benzodiazepin-2-yl)amino]phenyl]benzamide | n/a | |
| 40 | O14965_A0H | A0H | n/a | 49800151 | CHEMBL1230687 | N-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide | n/a | |
| 41 | O14965_A4W | A4W | n/a | 107022056 | n/a | ~{N}-(3-chloranyl-2-fluoranyl-phenyl)-3-sulfanyl-propanamide | n/a | |
| 42 | O14965_A5E | A5E | n/a | 723696 | n/a | 3-thiophen-2-yl-4,5-dihydro-1~{H}-pyridazin-6-one | n/a | |
| 43 | O14965_A5H | A5H | n/a | 73224 | n/a | 3-(4-chlorophenyl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole | n/a | |
| 44 | O14965_A5K | A5K | n/a | 735734 | n/a | 1-[3-chloranyl-5-(trifluoromethyl)pyridin-2-yl]-1,4-diazepane | n/a | |
| 45 | O14965_A5Q | A5Q | n/a | 2780715 | CHEMBL4570088 | 4-[4-(trifluoromethyl)phenyl]-1,2,3-thiadiazol-5-amine | n/a | |
| 46 | O14965_A5W | A5W | n/a | 2778070 | n/a | cyclobutyl-[4-(2-methoxyphenyl)piperidin-1-yl]methanone | n/a | |
| 47 | O14965_A5Z | A5Z | n/a | 2781686 | n/a | [3-[2,6-bis(chloranyl)phenyl]-5-methyl-1,2-oxazol-4-yl]methanol | n/a | |
| 48 | O14965_A65 | A65 | n/a | 2739015 | CHEMBL1891657 | [3,5-bis(methylsulfanyl)-1,2-thiazol-4-yl]methanol | n/a | |
| 49 | O14965_A6E | A6E | n/a | 2739507 | n/a | 3-(4-fluoranylphenoxy)-1-thiomorpholin-4-yl-propan-1-one | n/a | |
| 50 | O14965_A6H | A6H | n/a | 2798074 | CHEMBL1496674 | 6-[2,6-bis(chloranyl)phenoxy]pyridin-3-amine | n/a | |
| 51 | O14965_A6W | A6W | n/a | 2736807 | CHEMBL1508842 | methyl 3-azanyl-5-thiophen-2-yl-thiophene-2-carboxylate | n/a | |
| 52 | O14965_A6Z | A6Z | n/a | 6926352 | n/a | 2-[4-(3-chlorophenyl)piperazin-1-ium-1-yl]ethanenitrile | n/a | |
| 53 | O14965_A7H | A7H | n/a | 285325 | n/a | 6-ethoxy-2-methyl-1,3-benzothiazole | n/a | |
| 54 | O14965_A7K | A7K | n/a | 40432334 | n/a | [2-[4-(hydroxymethyl)piperidin-1-yl]phenyl]methylazanium | n/a | |
| 55 | O14965_A7N | A7N | n/a | 793474 | n/a | (1~{R})-1-(4-ethoxyphenyl)ethanamine | n/a | |
| 56 | O14965_A7Q | A7Q | n/a | 2776502 | n/a | (6-phenoxypyridin-3-yl)methanol | n/a | |
| 57 | O14965_A8H | A8H | n/a | 2733714 | n/a | (3~{a}~{R},5~{S},7~{a}~{S})-5-phenyl-3~{a},4,5,6,7,7~{a}-hexahydroisoindole-1,3-dione | n/a | |
| 58 | O14965_A8K | A8K | n/a | 17570 | CHEMBL3183502 | 4-(4-hydroxyphenyl)sulfanylphenol | n/a | |
| 59 | O14965_A98 | A98 | n/a | 1220743 | n/a | methyl ~{N}-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)carbamate | n/a | |
| 60 | O14965_A9B | A9B | n/a | 705834 | CHEMBL4127864 | 5-(4-chlorophenyl)furan-2-carbohydrazide | n/a | |
| 61 | O14965_A9E | A9E | n/a | 905454 | n/a | 2-(4-ethylphenoxy)-1-piperidin-1-yl-ethanone | n/a | |
| 62 | O14965_ACP | ACP | DB03909 | 91532 | CHEMBL133463 | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | n/a | |
| 63 | O14965_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 64 | O14965_ADN | ADN | DB00640 | 60961 | CHEMBL477 | ADENOSINE | n/a | |
| 65 | O14965_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 66 | O14965_AK8 | AK8 | n/a | 25113168 | CHEMBL468612 | 1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | n/a | |
| 67 | O14965_AKI | AKI | n/a | 44470172 | CHEMBL1173731 | 1-(4-{2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | n/a | |
| 68 | O14965_ANP | ANP | n/a | 33113 | CHEMBL1230989 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | n/a | |
| 69 | O14965_ARS | ARS | n/a | 23969 | CHEMBL1231052 | ARSENIC | n/a | |
| 70 | O14965_ASH | ASH | n/a | 49800150 | CHEMBL1231066 | 3-chloro-N-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine | n/a | |
| 71 | O14965_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 72 | O14965_AY4 | AY4 | n/a | 2804885 | n/a | 2,4-bis(fluoranyl)-6-(1~{H}-pyrazol-3-yl)phenol | n/a | |
| 73 | O14965_BCN | BCN | DB03709 | 8761;5256512; | CHEMBL1231251 | BICINE | n/a | |
| 74 | O14965_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 75 | O14965_CC3 | CC3 | DB07545 | 9549303 | CHEMBL383899 | N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE | n/a | IC50(nM) = 42.0 |
| 76 | O14965_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 77 | O14965_CJ5 | CJ5 | n/a | 77232197 | CHEMBL4756194 | 1-[4-[[4-[(5-cyclopentyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea | n/a | |
| 78 | O14965_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 79 | O14965_COA | COA | DB01992 | 87642 | CHEMBL1213327 | COENZYME A | n/a | |
| 80 | O14965_D36 | D36 | n/a | 53308639 | CHEMBL1825101 | N-(2-aminoethyl)-N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | n/a | |
| 81 | O14965_D37 | D37 | n/a | 53308640 | CHEMBL1825096 | N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | n/a | |
| 82 | O14965_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 83 | O14965_E47 | E47 | n/a | 168719756 | n/a | 5-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-oxidanyl-benzaldehyde | n/a | |
| 84 | O14965_E9Z | E9Z | n/a | 54765323 | n/a | 5-chloro-N~4~-cyclopropyl-N~2~-[4-(2-methoxyethoxy)phenyl]pyrimidine-2,4-diamine | n/a | |
| 85 | O14965_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 86 | O14965_EG7 | EG7 | DB18019 | 121333423 | n/a | (2R,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid | inhibitor | |
| 87 | O14965_EGJ | EGJ | n/a | 137319633 | n/a | (2S,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid | n/a | |
| 88 | O14965_EML | EML | n/a | 25144732 | CHEMBL1232515 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol | n/a | |
| 89 | O14965_F8Z | F8Z | n/a | 44484893 | CHEMBL3183436 | 1-[(2~{R},3~{S})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{S})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{H}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | n/a | |
| 90 | O14965_FH3 | FH3 | n/a | 71816173 | CHEMBL3087778 | (S)-N-((1-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)methyl)acetamide | n/a | |
| 91 | O14965_FH5 | FH5 | n/a | 71816174 | CHEMBL3087776 | (S)-N-(1-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)acetamide | n/a | |
| 92 | O14965_G7T | G7T | n/a | 137349404 | n/a | ~{N}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-3-methyl-phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-butanamide | n/a | |
| 93 | O14965_G7W | G7W | n/a | 134817555 | n/a | (~{E})-~{N}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-but-2-enamide | n/a | |
| 94 | O14965_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 95 | O14965_HPM | HPM | n/a | 5494424 | CHEMBL427212 | N-{5-[(7-{[(2S)-2-HYDROXY-3-PIPERIDIN-1-YLPROPYL]OXY}-6-METHOXYQUINAZOLIN-4-YL)AMINO]PYRIMIDIN-2-YL}BENZAMIDE | n/a | |
| 96 | O14965_JRQ | JRQ | n/a | 1382900 | n/a | ethyl 2-[(2~{R})-1-[(4-methylphenyl)methyl]-3-oxidanylidene-piperazin-2-yl]ethanoate | n/a | |
| 97 | O14965_JRT | JRT | n/a | 713331 | n/a | 2-(benzimidazol-1-yl)-~{N}-(2-phenylethyl)ethanamide | n/a | |
| 98 | O14965_JRW | JRW | n/a | 138115402 | n/a | (1~{S},10~{S})-12-cyclobutyl-5-methyl-1-oxidanyl-10-propan-2-yl-9,12-diazatricyclo[8.2.1.0^{2,7}]trideca-2(7),3,5-trien-11-one | n/a | |
| 99 | O14965_JSB | JSB | n/a | 138115401 | n/a | (1~{S},10~{S})-12-cyclopropyl-1-oxidanyl-10-propan-2-yl-9,12-diazatricyclo[8.2.1.0^{2,7}]trideca-2(7),3,5-trien-11-one | n/a | |
| 100 | O14965_JSN | JSN | n/a | n/a | n/a | (6~{S})-6-[2,4-bis(fluoranyl)phenyl]-~{N},~{N},4-trimethyl-2-oxidanylidene-5,6-dihydro-1~{H}-pyrimidine-5-carboxamide | n/a | |
| 101 | O14965_JVE | JVE | n/a | 117072315;137160099; | n/a | (4S)-4-(2-fluorophenyl)-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b][1,7]naphthyridin-5-one | n/a | |
| 102 | O14965_JWG | JWG | n/a | 11194800 | n/a | 4-(3-hydroxy-3-oxopropylamino)-4-oxidanylidene-butanoic acid | n/a | |
| 103 | O14965_L0C | L0C | n/a | 135566357 | n/a | 4-{[2-(4-{[(4-FLUOROPHENYL)CARBONYL]AMINO}-1H-PYRAZOL-3-YL)-1H-BENZIMIDAZOL-6-YL]METHYL}MORPHOLIN-4-IUM | n/a | |
| 104 | O14965_L0D | L0D | DB08065 | 763936 | CHEMBL495758 | 2-(1H-pyrazol-3-yl)-1H-benzimidazole | inhibitor | IC50(nM) = 910.0 |
| 105 | O14965_L0E | L0E | n/a | 135566359 | n/a | 4-[(2-{4-[(PHENYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-5-YL)METHYL]MORPHOLIN-4-IUM | n/a | |
| 106 | O14965_L0F | L0F | DB08066 | 135566361 | CHEMBL522891 | N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE | n/a | IC50(nM) = 5.9 |
| 107 | O14965_L0G | L0G | n/a | 135566362 | n/a | 2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-6-(MORPHOLIN-4-IUM-4-YLMETHYL)-1H-3,1-BENZIMIDAZOL-3-IUM | n/a | |
| 108 | O14965_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 109 | O14965_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 110 | O14965_MMH | MMH | n/a | 25223978 | CHEMBL515560 | N-[3-(acetylamino)phenyl]-5-{(2E)-2-[(4-methoxyphenyl)methylidene]hydrazino}-3-methyl-1H-pyrazole-4-carboxamide | n/a | |
| 111 | O14965_MPD | MPD | DB03564 | 5288834 | n/a | (4S)-2-METHYL-2,4-PENTANEDIOL | n/a | |
| 112 | O14965_MPY | MPY | n/a | n/a | n/a | (3E)-N-(2,6-DIETHYLPHENYL)-3-{[4-(4-METHYLPIPERAZIN-1-YL)BENZOYL]IMINO}PYRROLO[3,4-C]PYRAZOLE-5(3H)-CARBOXAMIDE | n/a | |
| 113 | O14965_N13 | N13 | n/a | 135566620 | n/a | 2-{3-[3-(1H-benzimidazol-2-yl)-1H-indazol-6-yl]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide | n/a | |
| 114 | O14965_N15 | N15 | n/a | 135566621 | n/a | 2-{4-[3-(1H-benzimidazol-2-yl)-1H-indazol-6-yl]-1H-pyrazol-1-yl}-N-(3-methylbutyl)acetamide | n/a | |
| 115 | O14965_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 116 | O14965_NHI | NHI | n/a | 779302 | CHEMBL2170598 | 4,4'-(pyrimidine-2,4-diyldiimino)dibenzoic acid | n/a | |
| 117 | O14965_NHJ | NHJ | n/a | 60138155 | CHEMBL3899351 | 4-[(4-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]benzamide | n/a | |
| 118 | O14965_NHU | NHU | n/a | 60138156 | CHEMBL2170596 | 2-({2-[(4-carbamoylphenyl)amino]pyrimidin-4-yl}amino)benzamide | n/a | |
| 119 | O14965_NL4 | NL4 | n/a | 91844457 | n/a | 3-((4-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)-1H-pyrazol-1-yl)methyl)-N,N-dimethylbenzamide | n/a | |
| 120 | O14965_NRM | NRM | n/a | 49867401 | CHEMBL1234822 | N-(3-methylisothiazol-5-yl)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine | n/a | |
| 121 | O14965_OFI | OFI | n/a | 135458003 | CHEMBL1082237 | N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]butanamide | n/a | |
| 122 | O14965_P4G | P4G | DB08357 | 8179 | CHEMBL1235106 | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE | n/a | |
| 123 | O14965_P9J | P9J | n/a | 11652621 | CHEMBL1615165 | 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2H)-one | n/a | |
| 124 | O14965_PDO | PDO | DB02774 | 10442 | CHEMBL379652 | 1,3-PROPANDIOL | n/a | |
| 125 | O14965_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 126 | O14965_PFQ | PFQ | DB08393 | 1587957 | CHEMBL189434 | 2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL | n/a | IC50(nM) = 273.0 |
| 127 | O14965_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 128 | O14965_PGF | PGF | n/a | 81860 | n/a | 2,5,8,11-TETRAOXATRIDECANE | n/a | |
| 129 | O14965_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 130 | O14965_Q7Q | Q7Q | n/a | 59442288 | n/a | 6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | n/a | |
| 131 | O14965_QMN | QMN | n/a | 49787166 | CHEMBL3393498 | ethyl (9S)-9-[3-(1H-benzimidazol-2-yloxy)phenyl]-8-oxo-4,5,6,7,8,9-hexahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate | n/a | |
| 132 | O14965_RO9 | RO9 | n/a | 23633432 | n/a | 1-(3-methoxyphenyl)-N-(5-methyl-1H-pyrazol-3-yl)isoquinolin-3-amine | n/a | |
| 133 | O14965_S9H | S9H | n/a | 155804535 | n/a | 7-[2-[(4-methoxyphenyl)amino]pyrimidin-4-yl]-1,3,4,5-tetrahydro-1-benzazepin-2-one | n/a | |
| 134 | O14965_S9K | S9K | n/a | 155294509 | n/a | 7-(2-phenylazanylpyrimidin-4-yl)-1,3,4,5-tetrahydro-1-benzazepin-2-one | n/a | |
| 135 | O14965_SKE | SKE | n/a | 5330790 | CHEMBL191003 | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide | n/a | |
| 136 | O14965_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 137 | O14965_V0K | V0K | n/a | 156621367 | n/a | 1-[[3,4-bis(fluoranyl)phenyl]methyl]-~{N}-[(1~{R})-2-[[(3~{E})-3-(1~{H}-imidazol-5-ylmethylidene)-2-oxidanylidene-1~{H}-indol-5-yl]amino]-2-oxidanylidene-1-phenyl-ethyl]-6-methyl-2-oxidanylidene-pyridine-3-carboxamide | n/a | |
| 138 | O14965_VEK | VEK | n/a | 70789751 | CHEMBL2207506 | 6-bromo-2-(1-methyl-1H-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1H-imidazo[4,5-b]pyridine | n/a | |
| 139 | O14965_VX6 | VX6 | n/a | 5494449 | CHEMBL572878 | CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE | n/a | |
| 140 | O14965_WPH | WPH | n/a | 44468256 | CHEMBL2398657 | 1-(4-{2-[(6-{4-[2-(dimethylamino)ethoxy]phenyl}furo[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | n/a | |
| 141 | O14965_X6D | X6D | n/a | 46224500 | CHEMBL1083772 | 6-BROMO-7-[4-(4-CHLOROBENZYL)PIPERAZIN-1-YL]-2-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]-3H-IMIDAZO[4,5-B]PYRIDINE | n/a | |
| 142 | O14965_XU1 | XU1 | n/a | 12342815 | CHEMBL110381 | benzo[c][1,8]naphthyridin-6(5H)-one | n/a | |
| 143 | O14965_XU2 | XU2 | n/a | 44189332 | CHEMBL2380845 | N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide | n/a | |
| 144 | O14965_Y3M | Y3M | n/a | n/a | n/a | ethyl (9S)-9-[5-(1H-benzimidazol-2-ylsulfanyl)furan-2-yl]-8-hydroxy-5,6,7,9-tetrahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate | n/a | |
| 145 | O14965_YM4 | YM4 | n/a | 25154041 | CHEMBL1236904 | 6-BROMO-7-{4-[(5-METHYLISOXAZOL-3-YL)METHYL]PIPERAZIN-1-YL}-2-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-IMIDAZO[4,5-B]PYRIDINE | n/a | |
| 146 | O14965_YPH | YPH | n/a | 57946373 | CHEMBL2398642 | 1-(4-{2-[(6-{4-[2-(4-hydroxypiperidin-1-yl)ethoxy]phenyl}furo[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | n/a | |
| 147 | O14965_ZZL | ZZL | DB13061 | 11712649 | CHEMBL259084 | 4-{[9-CHLORO-7-(2,6-DIFLUOROPHENYL)-5H-PYRIMIDO[5,4-D][2]BENZAZEPIN-2-YL]AMINO}BENZOIC ACID | inhibitor | |
| 148 | O14965_D11 | D11 | DB02482 | n/a | n/a | Phosphonothreonine | inhibitor | |
| 149 | O14965_A5B | A5B | DB05220 | 24771867 | CHEMBL483158 | Alisertib | inhibitor | |
| 150 | O14965_AK2 | AK2 | DB06134 | 24995524 | CHEMBL482767 | SNS-314 | inhibitor | |
| 151 | O14965_DB06347 | n/a | DB06347 | n/a | n/a | Cenisertib | inhibitor | |
| 152 | O14965_DB06486 | n/a | DB06486 | n/a | n/a | Enzastaurin | n/a | |
| 153 | O14965_AK1 | AK1 | DB07360 | 24880024 | CHEMBL472193 | 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea | n/a | IC50(nM) = 22.0 |
| 154 | O14965_AK3 | AK3 | DB07362 | 15602701 | n/a | 1-(5-{2-[(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea | n/a | |
| 155 | O14965_FXG | FXG | DB07801 | 24893974 | CHEMBL521105 | N-butyl-3-{[6-(9H-purin-6-ylamino)hexanoyl]amino}benzamide | n/a | |
| 156 | O14965_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |