Gene name: GAK
Protein name: Cyclin-G-associated kinase (EC
List of molecules and drugs that interact with protein O14976
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O14976_49J | 49J | n/a | 90467922 | CHEMBL3425867 | 2-methoxy-4-[3-(morpholin-4-yl)[1,2]thiazolo[4,3-b]pyridin-6-yl]aniline | n/a | |
| 2 | O14976_824 | 824 | DB04608 | 4369491 | CHEMBL214253 | 9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE | n/a | |
| 3 | O14976_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 4 | O14976_FEF | FEF | DB07766 | n/a | n/a | (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} | n/a | |
| 5 | O14976_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 6 | O14976_IRE | IRE | DB00317 | 123631 | CHEMBL939 | Gefitinib | n/a | IC50(nM) = 420.0 Kd(nM) = 7.0 |
| 7 | O14976_SIN | SIN | DB00139 | 1110;21952380; | CHEMBL576 | SUCCINIC ACID | n/a | |
| 8 | O14976_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 9 | O14976_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |