Gene name: nos
Protein name: Nitric oxide synthase
List of molecules and drugs that interact with protein O34453
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O34453_0GD | 0GD | n/a | 91809472 | n/a | 6-[4-({[2-(3-fluorophenyl)ethyl]amino}methyl)phenyl]-4-methylpyridin-2-amine | n/a | |
| 2 | O34453_12S | 12S | n/a | 71304800 | CHEMBL2326358 | 6,6'-{[5-(3-aminopropyl)benzene-1,3-diyl]diethane-2,1-diyl}bis(4-methylpyridin-2-amine) | n/a | |
| 3 | O34453_1ET | 1ET | n/a | 71260796 | CHEMBL2326360 | 6,6'-{[5-(aminomethyl)benzene-1,3-diyl]diethane-2,1-diyl}bis(4-methylpyridin-2-amine) | n/a | |
| 4 | O34453_1EV | 1EV | n/a | 71254035 | CHEMBL2326361 | 3,5-bis[2-(6-amino-4-methylpyridin-2-yl)ethyl]benzonitrile | n/a | |
| 5 | O34453_1EW | 1EW | n/a | 71304801 | CHEMBL2326359 | 6,6'-{[4-(3-aminopropyl)benzene-1,3-diyl]diethane-2,1-diyl}bis(4-methylpyridin-2-amine) | n/a | |
| 6 | O34453_1Q6 | 1Q6 | n/a | 71710900 | CHEMBL2430143 | 6,6'-{[(2S)-3-aminopropane-1,2-diyl]bis(oxymethanediyl)}bis(4-methylpyridin-2-amine) | n/a | |
| 7 | O34453_1QE | 1QE | n/a | 72725795 | CHEMBL3128241 | N,N'-(ethane-1,2-diyldibenzene-3,1-diyl)dithiophene-2-carboximidamide | n/a | |
| 8 | O34453_1QF | 1QF | n/a | 72725799 | CHEMBL3128247 | N-(4-{2-[ethyl(3-{[(E)-imino(thiophen-2-yl)methyl]amino}benzyl)amino]ethyl}phenyl)thiophene-2-carboximidamide | n/a | |
| 9 | O34453_2AQ | 2AQ | n/a | 11379 | CHEMBL61236 | QUINOLIN-2-AMINE | n/a | |
| 10 | O34453_2SN | 2SN | n/a | 91971387 | CHEMBL3736594 | 7-[[[3-[(dimethylamino)methyl]phenyl]amino]methyl]quinolin-2-amine | n/a | |
| 11 | O34453_4V4 | 4V4 | n/a | 91808024 | CHEMBL3586656 | N1-(3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)phenyl)-N1,N2-dimethylethane-1,2-diamine | n/a | |
| 12 | O34453_5H4 | 5H4 | n/a | 72725801 | CHEMBL3125049 | N-[3-({ethyl[2-(3-fluorophenyl)ethyl]amino}methyl)phenyl]thiophene-2-carboximidamide | n/a | |
| 13 | O34453_6E5 | 6E5 | n/a | 76936799 | CHEMBL3325614 | N-[3-({[(3S,5S)-5-{[(3-{[(Z)-imino(thiophen-2-yl)methyl]amino}benzyl)oxy]methyl}pyrrolidin-3-yl]oxy}methyl)phenyl]thiophene-2-carboximidamide | n/a | |
| 14 | O34453_7LN | 7LN | n/a | 76936798 | CHEMBL3325610 | N,N''-{[(2S)-3-aminopropane-1,2-diyl]bis(oxymethanediylbenzene-3,1-diyl)}dithiophene-2-carboximidamide | n/a | |
| 15 | O34453_7S9 | 7S9 | n/a | 91808027 | n/a | 6-[2-[5-[2-(dimethylamino)ethyl]pyridin-3-yl]ethyl]-4-methyl-pyridin-2-amine | n/a | |
| 16 | O34453_8VJ | 8VJ | n/a | 91971386 | CHEMBL3736592 | 7-[[4-[(dimethylamino)methyl]phenoxy]methyl]quinolin-2-amine | n/a | |
| 17 | O34453_9M9 | 9M9 | n/a | 91971385 | CHEMBL3736587 | 7-[[3-(aminomethyl)phenoxy]methyl]quinolin-2-amine | n/a | |
| 18 | O34453_ARG | ARG | DB00125 | 1549073;5287702;52941769;59294017;59904234;88031296; | n/a | ARGININE | n/a | |
| 19 | O34453_BTB | BTB | n/a | 81462 | n/a | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 20 | O34453_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 21 | O34453_EXI | EXI | n/a | 91808031 | CHEMBL3586661 | N1-(5-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)-N1,N2-dimethylethane-1,2-diamine | n/a | |
| 22 | O34453_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 23 | O34453_H2B | H2B | DB02562 | 133246;135398653; | n/a | 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE | n/a | |
| 24 | O34453_H36 | H36 | n/a | 72725796 | CHEMBL3128243 | N,N'-[ethane-1,2-diylbis(oxybenzene-3,1-diyl)]dithiophene-2-carboximidamide | n/a | |
| 25 | O34453_H49 | H49 | n/a | 91808029 | n/a | (S)-N-(3-(((Pyrrolidin-2-ylmethyl)amino)methyl)phenyl)thiophene-2-carboximidamide | n/a | |
| 26 | O34453_H4B | H4B | DB00360 | 44257;5282445;135398654; | CHEMBL1201774 | 5,6,7,8-TETRAHYDROBIOPTERIN | n/a | |
| 27 | O34453_H8B | H8B | n/a | 121596958 | n/a | 7-[[2-(methylaminomethyl)phenoxy]methyl]quinolin-2-amine | n/a | |
| 28 | O34453_HAR | HAR | DB03144 | 123895;25799416; | CHEMBL260629 | N-OMEGA-HYDROXY-L-ARGININE | n/a | |
| 29 | O34453_HBI | HBI | DB04400 | 119055;5288515;135398687; | n/a | 7,8-DIHYDROBIOPTERIN | n/a | |
| 30 | O34453_HEC | HEC | DB03317 | n/a | n/a | HEME C | n/a | |
| 31 | O34453_HEM | HEM | DB18267 | n/a | n/a | PROTOPORPHYRIN IX CONTAINING FE | n/a | |
| 32 | O34453_HW1 | HW1 | n/a | 57345937 | n/a | 6-[5-({(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pentyl]-4-methylpyridin-2-amine | n/a | |
| 33 | O34453_I5U | I5U | n/a | 76936797 | CHEMBL3325609 | N',N'-{[(2R)-3-aminopropane-1,2-diyl]bis(oxymethanediylbenzene-3,1-diyl)}dithiophene-2-carboximidamide | n/a | |
| 34 | O34453_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 35 | O34453_INE | INE | DB01997 | 1649 | CHEMBL479014 | 3-BROMO-7-NITROINDAZOLE | n/a | |
| 36 | O34453_IVU | IVU | n/a | 86346620 | CHEMBL3394386 | 3-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-5-{2-[4-METHYL-6-(METHYLAMINO)PYRIDIN-2-YL]ETHYL}BENZONITRILE | n/a | |
| 37 | O34453_JHT | JHT | n/a | 121596956 | CHEMBL4096369 | 7-[[[3-(dimethylamino)phenyl]methylamino]methyl]quinolin-2-amine | n/a | |
| 38 | O34453_M46 | M46 | n/a | 72771079 | CHEMBL3139616 | 7-[2-[3-(3-fluorophenyl)propylamino]ethyl]quinolin-2-amine | n/a | |
| 39 | O34453_M48 | M48 | n/a | 72771082 | CHEMBL3139679 | 7-[2-[2-(3-fluorophenyl)ethylamino]ethyl]quinolin-2-amine | n/a | |
| 40 | O34453_M5K | M5K | n/a | 231935 | CHEMBL2011275 | 4-METHYLQUINOLIN-2-AMINE | n/a | |
| 41 | O34453_M7K | M7K | n/a | 72771078 | CHEMBL3139027 | 7-{2-[(3-fluorobenzyl)amino]ethyl}quinolin-2-amine | n/a | |
| 42 | O34453_M85 | M85 | n/a | 91971384 | CHEMBL3736586 | 7-[[3-(methylaminomethyl)phenoxy]methyl]quinolin-2-amine | n/a | |
| 43 | O34453_M87 | M87 | n/a | 72771077 | CHEMBL3139371 | 7-[[2-(3-fluorophenyl)ethylamino]methyl]quinolin-2-amine | n/a | |
| 44 | O34453_M94 | M94 | n/a | 91971382 | CHEMBL3736584 | 7-[[3-[2-(methylamino)ethyl]phenoxy]methyl]quinolin-2-amine | n/a | |
| 45 | O34453_ML6 | ML6 | n/a | 72771080 | CHEMBL3139608 | 7-({[3-(3-fluorophenyl)propyl]amino}methyl)quinolin-2-amine | n/a | |
| 46 | O34453_NO | NO | n/a | 945 | CHEMBL1234765 | NITRIC OXIDE | n/a | |
| 47 | O34453_NRG | NRG | DB04223 | 440005;28360916;135409365;135453301;155903772; | CHEMBL227744 | N-OMEGA-NITRO-L-ARGININE | n/a | |
| 48 | O34453_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 49 | O34453_POL | POL | DB03175 | 1031 | CHEMBL14687 | N-PROPANOL | n/a | |
| 50 | O34453_PQW | PQW | n/a | 76936800 | CHEMBL3327299 | N'-[4-[[(2S,4R)-4-[3-[(C-thiophen-2-ylcarbonimidoyl)amino]phenoxy]pyrrolidin-2-yl]methoxy]phenyl]thiophene-2-carboximidamide | n/a | |
| 51 | O34453_Q05 | Q05 | n/a | 71627413 | CHEMBL2414435 | 6-{[3-({[2-(3-fluorophenyl)ethyl]amino}methyl)phenoxy]methyl}-4-methylpyridin-2-amine | n/a | |
| 52 | O34453_Q13 | Q13 | n/a | 71710903 | CHEMBL2430150 | 6,6'-{[(2S,3S)-2-aminobutane-1,3-diyl]bis(oxymethanediyl)}bis(4-methylpyridin-2-amine) | n/a | |
| 53 | O34453_Q14 | Q14 | n/a | 71710902 | CHEMBL2430148 | 6-[({(2S)-1-amino-4-[(6-amino-4-methylpyridin-2-yl)methoxy]butan-2-yl}oxy)methyl]-4-methylpyridin-2-amine | n/a | |
| 54 | O34453_Q15 | Q15 | n/a | 71627412 | CHEMBL2414432 | 4-methyl-6-{[3-(piperidin-4-ylmethoxy)phenoxy]methyl}pyridin-2-amine | n/a | |
| 55 | O34453_Q16 | Q16 | n/a | 73386633 | CHEMBL3109188 | 6-((((3S, 5R)-5-(((6-amino-4-methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine | n/a | |
| 56 | O34453_Q1T | Q1T | n/a | 91808026 | CHEMBL3586664 | 3-(2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL)-5-(METHYL(2-(METHYLAMINO)ETHYL)AMINO)BENZONITRILE | n/a | |
| 57 | O34453_QJ7 | QJ7 | n/a | 71627414 | CHEMBL2414437 | 6-({[5-({[2-(3-fluorophenyl)ethyl]amino}methyl)pyridin-3-yl]oxy}methyl)-4-methylpyridin-2-amine | n/a | |
| 58 | O34453_QJ8 | QJ8 | n/a | 71741443 | CHEMBL3109186 | 6-({[(3R,5S)-5-{[(6-amino-4-methylpyridin-2-yl)methoxy]methyl}pyrrolidin-3-yl]oxy}methyl)-4-methylpyridin-2-amine | n/a | |
| 59 | O34453_RFQ | RFQ | n/a | 86346623 | n/a | N-{3-[(1S)-2-(3-{(Z)-[amino(thiophen-2-yl)methylidene]amino}phenoxy)-1-hydroxyethyl]phenyl}thiophene-2-carboximidamide | n/a | |
| 60 | O34453_S5D | S5D | n/a | 73659113 | CHEMBL3262018 | (R)-6-(2-Amino-2-(3-(2-(6-amino-4-methylpyridin-2-yl)ethyl)phenyl)ethyl)-4-methylpyridin-2-amine | n/a | |
| 61 | O34453_S90 | S90 | n/a | 91808028 | n/a | N1-(3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-fluorophenyl)-N1-cyclopropyl-N2-methylethane-1,2-diamine | n/a | |
| 62 | O34453_S97 | S97 | n/a | 86346622 | CHEMBL3394388 | 6-(2-{3-(aminomethyl)-5-[2-(1H-pyrrolo[2,3-b]pyridin-6-yl)ethyl]phenyl}ethyl)-4-methylpyridin-2-amine | n/a | |
| 63 | O34453_SK6 | SK6 | n/a | 86346621 | CHEMBL3394387 | 3-[2-(6-amino-4-methylpyridin-2-yl)ethyl]-5-{[2-(pyridin-2-yl)ethyl]amino}benzonitrile | n/a | |
| 64 | O34453_SKO | SKO | n/a | 91808025 | CHEMBL3586660 | N'-[6-[2-(6-AZANYL-4-METHYL-PYRIDIN-2-YL)ETHYL]PYRIDIN-2-YL]-N,N'-DIMETHYL-ETHANE-1,2-DIAMINE | n/a | |
| 65 | O34453_THG | THG | DB02031 | 5289465;5460413;135398650; | n/a | (6S)-5,6,7,8-TETRAHYDROFOLATE | n/a | |
| 66 | O34453_TUE | TUE | n/a | 137350063 | n/a | 7-[[5-[(methylideneamino)methyl]pyridin-3-yl]oxymethyl]quinolin-2-amine | n/a | |
| 67 | O34453_UGT | UGT | n/a | 91808030 | n/a | N-[3-[[(3R)-pyrrolidin-3-yl]oxymethyl]phenyl]thiophene-2-carboximidamide | n/a | |
| 68 | O34453_V0P | V0P | n/a | 155923467 | n/a | 7-{[3-(2-{[(6-aminopyridin-2-yl)methyl]amino}ethoxy)phenoxy]methyl}quinolin-2-amine | n/a | |
| 69 | O34453_V4V | V4V | n/a | 155926525 | n/a | 7-{[3-({[(pyridin-2-yl)methyl]amino}methyl)phenoxy]methyl}quinolin-2-amine | n/a | |
| 70 | O34453_V4Y | V4Y | n/a | 155926527 | n/a | 7-{[3-({[3-(6-aminopyridin-2-yl)propyl]amino}methyl)phenoxy]methyl}quinolin-2-amine | n/a | |
| 71 | O34453_V54 | V54 | n/a | 155926530 | n/a | 7-{[3-({[(6-aminopyridin-2-yl)methyl]amino}methyl)phenoxy]methyl}quinolin-2-amine | n/a | |
| 72 | O34453_V57 | V57 | n/a | 155926528 | n/a | 7-{[3-({[2-(pyridin-2-yl)ethyl]amino}methyl)phenoxy]methyl}quinolin-2-amine | n/a | |
| 73 | O34453_V5D | V5D | n/a | 155926526 | n/a | 7-{[3-({[4-(6-aminopyridin-2-yl)butyl]amino}methyl)phenoxy]methyl}quinolin-2-amine | n/a | |
| 74 | O34453_V5G | V5G | n/a | 155926529 | n/a | 7-({3-[2-(6-aminopyridin-2-yl)ethyl]phenoxy}methyl)quinolin-2-amine | n/a | |
| 75 | O34453_XEB | XEB | n/a | 91971388 | CHEMBL3736597 | 7-[[4-chloranyl-3-(methylaminomethyl)phenoxy]methyl]quinolin-2-amine | n/a | |
| 76 | O34453_XFJ | XFJ | n/a | 46847260 | CHEMBL1615288 | 6,6'-(pyridine-3,5-diyldiethane-2,1-diyl)bis(4-methylpyridin-2-amine) | n/a | |
| 77 | O34453_XFK | XFK | n/a | 46892823 | CHEMBL1615289 | 6-(2-{5-[2-(2-amino-6-methylpyridin-4-yl)ethyl]pyridin-3-yl}ethyl)-4-methylpyridin-2-amine | n/a | |
| 78 | O34453_XFN | XFN | n/a | 49852670 | CHEMBL1615292 | 6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]bis(4-methylpyridin-2-amine) | n/a | |
| 79 | O34453_XH8 | XH8 | n/a | 121596957 | CHEMBL4071836 | 7-(((3-(PYRIDIN-3-YL)PROPYL)AMINO)METHYL)QUINOLIN-2- | n/a |