Gene name: Pik3cd
Protein name: Phosphatidylinositol 4,5-bisphosphate 3-kinase
List of molecules and drugs that interact with protein O35904
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O35904_40L | 40L | DB09054 | 11625818 | CHEMBL2216870 | 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4(3H)-one | n/a | |
| 2 | O35904_67T | 67T | n/a | 76286865 | CHEMBL3805430 | 2,4-diamino-6-{[(1S)-1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl]amino}pyrimidine-5-carbonitrile | n/a | |
| 3 | O35904_68R | 68R | n/a | 76287717 | CHEMBL3806195 | 2-[(1S)-1-({6-amino-5-[(1H-pyrazol-4-yl)ethynyl]pyrimidin-4-yl}amino)ethyl]-5-chloro-3-phenylquinazolin-4(3H)-one | n/a | |
| 4 | O35904_6PF | 6PF | n/a | 121232438 | n/a | N-[6-(5-methanesulfonamido-6-methoxypyridin-3-yl)-1,3-dihydro-2-benzofuran-4-yl]-2-(morpholin-4-yl)acetamide | n/a | |
| 5 | O35904_74F | 74F | n/a | 126480568 | CHEMBL4090281 | 3-(benzotriazol-1-yl)-5-[1-methyl-5-[(1~{S})-1-morpholin-4-ylethyl]-1,2,4-triazol-3-yl]pyrazin-2-amine | n/a | |
| 6 | O35904_74H | 74H | n/a | 126480573 | CHEMBL4063902 | 1-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]pyrazole-3-carboxamide | n/a | |
| 7 | O35904_74J | 74J | n/a | 126480572 | CHEMBL4099419 | 1-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]pyrazole-4-carboxamide | n/a | |
| 8 | O35904_74K | 74K | n/a | 126480571 | CHEMBL4061055 | 4-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]pyrazole-1-carboxamide | n/a | |
| 9 | O35904_74L | 74L | n/a | 126480570 | CHEMBL4072500 | 4-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]-~{N},~{N}-dimethyl-pyrazole-1-sulfonamide | n/a | |
| 10 | O35904_74N | 74N | n/a | 126480574 | CHEMBL4091680 | 4-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]benzamide | n/a | |
| 11 | O35904_74O | 74O | n/a | 126480569 | CHEMBL4091640 | 5-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]-3-(1~{H}-pyrazol-4-yl)pyrazin-2-amine | n/a | |
| 12 | O35904_74Q | 74Q | n/a | 126476620 | CHEMBL4061634 | 3-(benzotriazol-1-yl)-5-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-amine | n/a | |
| 13 | O35904_76C | 76C | n/a | 86762886 | CHEMBL3909674 | 2,4-bis(azanyl)-6-[[(1~{S})-1-[5-chloranyl-3-(5-fluoranyl-4-methyl-pyridin-3-yl)-4-oxidanylidene-quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile | n/a | |
| 14 | O35904_77C | 77C | n/a | 86763204 | CHEMBL3928407 | 2,4-diamino-6-{[(S)-[5-chloro-8-fluoro-4-oxo-3-(pyridin-3-yl)-3,4-dihydroquinazolin-2-yl](cyclopropyl)methyl]amino}pyrimidine-5-carbonitrile | n/a | |
| 15 | O35904_7VT | 7VT | n/a | 156600271 | CHEMBL4876289 | 5-[3,6-dihydro-2H-pyran-4-yl]-2-methoxy-N-[2-methylpyridin-4-yl]pyridine-3-sulfonamide | n/a | |
| 16 | O35904_7XH | 7XH | n/a | 130302563 | CHEMBL4167702 | ~{N}-[2-[2-fluoranyl-4-[(4-propan-2-ylpiperazin-1-yl)methyl]phenyl]pyridin-4-yl]-2-methoxy-5-morpholin-4-yl-pyridine-3-sulfonamide | n/a | |
| 17 | O35904_7XN | 7XN | n/a | 156600272 | CHEMBL4872328 | 5-(3,6-dihydro-2~{H}-pyran-4-yl)-2-methoxy-~{N}-[5-[3-(4-propan-2-ylpiperazin-1-yl)prop-1-ynyl]pyridin-3-yl]pyridine-3-sulfonamide | n/a | |
| 18 | O35904_7XW | 7XW | n/a | 155534269 | CHEMBL4469876 | N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-pyridin-3-yl]benzenesulfonamide | n/a | |
| 19 | O35904_8TK | 8TK | n/a | 137348751 | CHEMBL4073594 | 4-azanyl-6-[[(1~{S})-1-(3-methyl-5-oxidanylidene-6-phenyl-[1,3]thiazolo[3,2-a]pyridin-7-yl)ethyl]amino]pyrimidine-5-carbonitrile | n/a | |
| 20 | O35904_8TN | 8TN | n/a | 137348752 | n/a | 4-azanyl-6-[[(1~{S})-1-[6-[3-[(dimethylamino)methyl]phenyl]-3-methyl-5-oxidanylidene-[1,3]thiazolo[3,2-a]pyridin-7-yl]ethyl]amino]pyrimidine-5-carbonitrile | n/a | |
| 21 | O35904_9NQ | 9NQ | DB16217 | 57495353 | CHEMBL3643413 | Leniolisib | n/a | |
| 22 | O35904_C5Z | C5Z | n/a | 131953539 | n/a | methyl 2-methoxy-5-[4-[5-[(4-propan-2-ylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl]-2~{H}-indazol-6-yl]pyridine-3-carboxylate | n/a | |
| 23 | O35904_E78 | E78 | n/a | 134163708 | CHEMBL4126445 | ~{N}-[5-[2-[(1~{S})-1-cyclopropylethyl]-7-methyl-1-oxidanylidene-3~{H}-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide | n/a | |
| 24 | O35904_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 25 | O35904_FGE | FGE | n/a | 137322697 | n/a | ~{N}-[4-methyl-5-(1-oxidanylidene-7-sulfamoyl-isoindol-5-yl)-1,3-thiazol-2-yl]ethanamide | n/a | |
| 26 | O35904_G5T | G5T | n/a | 16049523 | n/a | 3-(6-morpholin-4-ylpyridin-2-yl)phenol | n/a | |
| 27 | O35904_G62 | G62 | n/a | 139030255 | n/a | 3-[6-[(1~{S},6~{R})-3-oxabicyclo[4.1.0]heptan-6-yl]pyridin-2-yl]phenol | n/a | |
| 28 | O35904_GFJ | GFJ | n/a | 134372959 | CHEMBL4470860 | 4-[1-(5,8-difluoroquinolin-4-yl)-2-methyl-4-(4H-1,2,4-triazol-3-yl)-1H-benzimidazol-6-yl]-3-fluoropyridin-2-amine | n/a | |
| 29 | O35904_H5I | H5I | n/a | 71715594 | n/a | (4~{S})-3-[6-[2-azanyl-4-(trifluoromethyl)pyrimidin-5-yl]-2-morpholin-4-yl-pyrimidin-4-yl]-4-methyl-1,3-oxazolidin-2-one | n/a | |
| 30 | O35904_HKK | HKK | n/a | 135397763 | CHEMBL4476588 | ~{N}-[2-chloranyl-5-(3,6-dihydro-2~{H}-pyran-4-yl)pyridin-3-yl]methanesulfonamide | n/a | |
| 31 | O35904_HKN | HKN | n/a | 135397764 | CHEMBL4435246 | ~{N}-[5-(3,6-dihydro-2~{H}-pyran-4-yl)-2-methoxy-pyridin-3-yl]-2-methyl-1-(phenylmethyl)imidazole-4-sulfonamide | n/a | |
| 32 | O35904_HKQ | HKQ | n/a | 25266674 | CHEMBL4555426 | ~{N}-(2-chloranyl-5-phenyl-pyridin-3-yl)benzenesulfonamide | n/a | |
| 33 | O35904_J82 | J82 | n/a | 49854424;135565159; | CHEMBL3112866 | 2-[2-(2-METHYL-2,3-DIHYDRO-INDOL-1-YL)-2-OXO-ETHYL]-6-MORPHOLIN-4-YL-3H-PYRIMIDIN-4-ONE | n/a | |
| 34 | O35904_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 35 | O35904_NQ2 | NQ2 | n/a | 129626595 | CHEMBL4556087 | ~{N}-[2-methoxy-5-[7-[2-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide | n/a | |
| 36 | O35904_NQ5 | NQ5 | n/a | 145946093 | CHEMBL4579923 | 2-methoxy-~{N}-[2-methoxy-5-[7-[[(2~{R})-4-(oxetan-3-yl)morpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]ethanesulfonamide | n/a | |
| 37 | O35904_OKO | OKO | n/a | 49783923 | CHEMBL4434674 | N-[5-[4-(5-{[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]METHYL}-1,3-OXAZOL-2-YL)-1H-INDAZOL-6-YL]-2-(METHYLOXY)-3-PYRIDINYL]METHANESULFONAMIDE | n/a | |
| 38 | O35904_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 39 | O35904_QD2 | QD2 | n/a | 146675166 | n/a | 4-[6-methoxy-5-(methylsulfamoyl)pyridin-3-yl]-~{N}-(1-methylpiperidin-4-yl)-2,3-dihydro-1,4-benzoxazine-6-carboxamide | n/a | |
| 40 | O35904_QDE | QDE | n/a | 146672979 | CHEMBL4645570 | ~{N}-[5-[6-[(dimethylamino)methyl]-2,3-dihydro-1,4-benzoxazin-4-yl]-2-methoxy-pyridin-3-yl]methanesulfonamide | n/a | |
| 41 | O35904_QDW | QDW | n/a | 146680869 | CHEMBL4638471 | methoxymethyloxathiatetraazatetracyclodocosahexaenedione | n/a | |
| 42 | O35904_SD5 | SD5 | DB11666 | 16654980 | CHEMBL2017974 | 5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine | n/a | |
| 43 | O35904_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 44 | O35904_VEH | VEH | n/a | 155937515 | CHEMBL5076518 | 6-[[5-[2-[(1S)-1-cyclopropylethyl]-7-(methylsulfamoyl)-1-oxidanylidene-3H-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]amino]-N-[3-(dimethylamino)propyl]pyridine-2-carboxamide | n/a | |
| 45 | O35904_VEN | VEN | n/a | 141754136 | CHEMBL4558527 | 2-[(1S)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxidanylidenepyrrolidin-1-yl)pyridin-2-yl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3H-isoindol-1-one | n/a | |
| 46 | O35904_VEQ | VEQ | n/a | 155937514 | CHEMBL5077792 | N-[5-[2-[(1S)-1-cyclopropylethyl]-7-[[4-[(dimethylamino)methyl]phenyl]sulfamoyl]-1-oxidanylidene-3H-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide | n/a | |
| 47 | O35904_VEW | VEW | n/a | 155937517 | CHEMBL5082486 | N-[5-[2-[(1S)-1-cyclopropylethyl]-7-[(3-methylsulfonylphenyl)sulfamoyl]-1-oxidanylidene-3H-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide | n/a | |
| 48 | O35904_VVX | VVX | DB16253 | 49784002 | CHEMBL2216859 | 6-(1H-Indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole | n/a | |
| 49 | O35904_VWN | VWN | n/a | 49853823;135566644; | CHEMBL2064330 | 2-[(1-methyl-1H-benzimidazol-2-yl)methyl]-6-morpholin-4-ylpyrimidin-4(3H)-one | n/a |