Gene name: MAP3K7
Protein name: Mitogen-activated protein kinase
List of molecules and drugs that interact with protein O43318
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O43318_1FM | 1FM | n/a | 9863776 | CHEMBL1077979 | (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione | n/a | |
| 2 | O43318_1UH | 1UH | n/a | 53379253 | CHEMBL2407766 | 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine | n/a | |
| 3 | O43318_1UL | 1UL | n/a | 53379038 | CHEMBL2407759 | 1-(4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]-1H-pyrazol-1-yl}piperidin-1-yl)ethanone | n/a | |
| 4 | O43318_1UO | 1UO | n/a | n/a | CHEMBL2408611 | trans-4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-chlorofuro[2,3-c]pyridin-4-yl]-1H-pyrazol-1-yl}cyclohexanol | n/a | |
| 5 | O43318_5KW | 5KW | n/a | 132819860 | CHEMBL3883823 | 2-chloro-N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}acetamide | n/a | |
| 6 | O43318_6H3 | 6H3 | n/a | 134130572 | CHEMBL3884293 | N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | n/a | |
| 7 | O43318_6H4 | 6H4 | n/a | 132819862 | CHEMBL3884960 | N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | n/a | |
| 8 | O43318_6HF | 6HF | n/a | 122490483 | CHEMBL3885166 | N-(4-((2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)phenyl)acrylamide | n/a | |
| 9 | O43318_6JV | 6JV | n/a | 121232427;135567180; | CHEMBL3823335 | N-(2-methoxy-4-{[3-(4-methylpiperazin-1-yl)propyl]carbamoyl}phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide | n/a | |
| 10 | O43318_6KC | 6KC | n/a | 121232426;135567179; | CHEMBL3823127 | N-[5-(4-methylpiperazine-1-carbonyl)[1,1'-biphenyl]-2-yl]-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide | n/a | |
| 11 | O43318_6KD | 6KD | n/a | 121232428;135567181; | CHEMBL3823738 | N-(2-isopropoxy-3-(4-methylpiperazine-1-carbonyl)phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide | n/a | |
| 12 | O43318_6L4 | 6L4 | n/a | 132819865 | CHEMBL3884143 | ~{N}-[2-[5-chloranyl-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide | n/a | |
| 13 | O43318_6V3 | 6V3 | n/a | 122235218 | CHEMBL4095421 | 1-(4-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)-3-(5-(4-methylpiperazin-1-yl)naphthalen-2-yl)urea | n/a | |
| 14 | O43318_6V4 | 6V4 | n/a | 122235219 | n/a | N-(2-isopropoxy-4-(4-methylpiperazine-1-carbonyl)phenyl)-2-(3-(3-phenylureido)phenyl)thiazole-4-carboxamide | n/a | |
| 15 | O43318_6V5 | 6V5 | n/a | 122235220 | n/a | N-(2-isopropoxy-4-(4-methylpiperazine-1-carbonyl)phenyl)-2-(3-(phenylcarbamoyl)phenyl)thiazole-4-carboxamide | n/a | |
| 16 | O43318_ADN | ADN | DB00640 | 60961 | CHEMBL477 | ADENOSINE | n/a | Kd(nM) = 4400.0 |
| 17 | O43318_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 18 | O43318_EDH | EDH | n/a | 37750349 | CHEMBL5414193 | N~1~-(1-propyl-1,3-dihydro-2H-benzimidazol-2-ylidene)benzene-1,3-dicarboxamide | n/a | |
| 19 | O43318_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 20 | O43318_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 21 | O43318_NG2 | NG2 | n/a | 53340664 | CHEMBL4125960 | N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide | n/a | |
| 22 | O43318_URW | URW | n/a | 155883050 | n/a | 2-[[5-[[2-[bis(fluoranyl)methoxy]phenyl]methyl-[(2~{R})-1-(methylamino)-1-oxidanylidene-propan-2-yl]carbamoyl]-1~{H}-imidazol-2-yl]carbonyl]isoindole-5-carboxamide | n/a | |
| 23 | O43318_UWZ | UWZ | n/a | 155883051 | CHEMBL4779479 | ~{N}-[[2-[bis(fluoranyl)methoxy]phenyl]methyl]-~{N}-[2-(methylamino)-2-oxidanylidene-ethyl]-2-pyrrolidin-1-ylcarbonyl-1~{H}-imidazole-4-carboxamide | n/a | |
| 24 | O43318_YIY | YIY | n/a | n/a | n/a | (1E)-1-[5-TERT-BUTYL-2-(3-FLUOROPHENYL)-1H-PYRAZOL-3-YLIDENE]-3-(4-PYRIDIN-3-YLOXYPHENYL)UREA | n/a | |
| 25 | O43318_T92 | T92 | n/a | 132819859 | CHEMBL3884569 | 2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl prop-2-enoate | n/a |