Gene name: CA12
Protein name: Carbonic anhydrase 12
List of molecules and drugs that interact with protein O43570
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O43570_3TV | 3TV | n/a | 71584199 | CHEMBL2333418 | 2,3,5,6-tetrafluoro-4-(propylsulfanyl)benzenesulfonamide | n/a | |
| 2 | O43570_5EF | 5EF | n/a | 73774788 | n/a | 3-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | n/a | |
| 3 | O43570_6YH | 6YH | n/a | 127045752 | CHEMBL3797385 | 4-[2-(benzimidazol-1-yl)ethanoyl]benzenesulfonamide | n/a | |
| 4 | O43570_6YQ | 6YQ | n/a | 127047846 | CHEMBL3798446 | 4-[2-(benzimidazol-1-yl)ethanoyl]-2-chloranyl-benzenesulfonamide | n/a | |
| 5 | O43570_6Z9 | 6Z9 | n/a | 73774930 | n/a | 3-[(1S)-1,2,3,4-Tetrahydronapthalen-1-ylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | n/a | |
| 6 | O43570_7VZ | 7VZ | n/a | 162394490 | n/a | methyl 2-chloranyl-4-cyclohexylsulfanyl-5-sulfamoyl-benzoate | n/a | |
| 7 | O43570_84I | 84I | n/a | 162394492 | n/a | methyl 2-chloranyl-4-(2-phenylethylsulfanyl)-5-sulfamoyl-benzoate | n/a | |
| 8 | O43570_84O | 84O | n/a | 126508224 | n/a | methyl 4-chloranyl-2-cyclohexylsulfanyl-5-sulfamoyl-benzoate | n/a | |
| 9 | O43570_84Z | 84Z | n/a | 126508404 | n/a | methyl 4-chloranyl-2-(phenylsulfonyl)-5-sulfamoyl-benzoate | n/a | |
| 10 | O43570_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 11 | O43570_ACY | ACY | DB03166 | 176;21980959;160748163; | CHEMBL539 | ACETIC ACID | n/a | |
| 12 | O43570_AZM | AZM | DB00819 | 1986 | CHEMBL20 | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | inhibitor | Ki(nM) = 2.5 IC50(nM) = 5.7 Kd(nM) = 24.0 |
| 13 | O43570_CD | CD | n/a | 31193 | n/a | CADMIUM ION | n/a | |
| 14 | O43570_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 15 | O43570_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 16 | O43570_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 17 | O43570_E1F | E1F | n/a | 71768355 | CHEMBL2443188 | 2-chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide | n/a | |
| 18 | O43570_E1G | E1G | n/a | 71768357 | CHEMBL2443189 | 3-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide | n/a | |
| 19 | O43570_EA3 | EA3 | n/a | 126508406 | CHEMBL4450545 | 4-chloranyl-2-cyclohexylsulfanyl-~{N}-(2-hydroxyethyl)-5-sulfamoyl-benzamide | n/a | |
| 20 | O43570_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 21 | O43570_EM5 | EM5 | n/a | 12698194 | CHEMBL4176828 | 4-chloranyl-2-(cyclohexylamino)-~{N}-(2-hydroxyethyl)-5-sulfamoyl-benzamide | n/a | |
| 22 | O43570_EOQ | EOQ | n/a | 126508711 | CHEMBL4168966 | 4-chloranyl-~{N}-(2-hydroxyethyl)-2-[(phenylmethyl)amino]-5-sulfamoyl-benzamide | n/a | |
| 23 | O43570_J8Q | J8Q | n/a | 126508480 | CHEMBL4466140 | ~{N}-butyl-4-chloranyl-2-(2-phenylethylsulfanyl)-5-sulfamoyl-benzamide | n/a | |
| 24 | O43570_J92 | J92 | n/a | 126508837 | CHEMBL4588838 | methyl 4-[(4-chloranyl-2-cyclohexylsulfanyl-5-sulfamoyl-phenyl)carbonylamino]butanoate | n/a | |
| 25 | O43570_J95 | J95 | n/a | 12698199 | CHEMBL4174214 | ~{N}-butyl-4-chloranyl-2-(cyclohexylamino)-5-sulfamoyl-benzamide | n/a | |
| 26 | O43570_JTW | JTW | n/a | 126509224 | CHEMBL4443095 | 4-chloranyl-~{N}-(2-hydroxyethyl)-2-(phenylsulfonyl)-5-sulfamoyl-benzamide | n/a | |
| 27 | O43570_MKQ | MKQ | n/a | 142668866 | n/a | 3,5-diphenylbenzenesulfonamide | n/a | |
| 28 | O43570_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 29 | O43570_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 30 | O43570_V13 | V13 | n/a | 71299337 | CHEMBL2333417 | 2,3,5,6-tetrafluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | n/a | |
| 31 | O43570_V14 | V14 | n/a | 73774785 | CHEMBL3359181 | 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | n/a | |
| 32 | O43570_V1F | V1F | n/a | 73776642 | n/a | 3-(benzylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide | n/a | |
| 33 | O43570_V50 | V50 | n/a | 71299336 | CHEMBL2333410 | 4-[(4,6-dimethylpyrimidin-2-yl)thio]-2,3,5,6-tetrafluorobenzenesulfonamide | n/a | |
| 34 | O43570_VD8 | VD8 | n/a | 786792 | n/a | 3,5-di~{tert}-butylbenzenesulfonamide | n/a | |
| 35 | O43570_VD9 | VD9 | n/a | 71720662 | CHEMBL2333400 | 4-(propylsulfanyl)benzenesulfonamide | n/a | |
| 36 | O43570_WWO | WWO | n/a | 73774784 | CHEMBL4085190 | 3-(benzylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | n/a | |
| 37 | O43570_WWX | WWX | n/a | 91667929 | n/a | 2,3,6-trifluoro-5-{[(1R,2S)-2-hydroxy-1,2-diphenylethyl]amino}-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | n/a | |
| 38 | O43570_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 39 | O43570_DB00562 | n/a | DB00562 | n/a | n/a | Benzthiazide | inhibitor | |
| 40 | O43570_HFZ | HFZ | DB00774 | 3647 | CHEMBL1763 | Hydroflumethiazide | inhibitor | Ki(nM) = 305.0 |
| 41 | O43570_ZON | ZON | DB00909 | 5734;11967800; | CHEMBL750 | Zonisamide | inhibitor | Ki(nM) = 11000.0 |
| 42 | O43570_REF | REF | DB08846 | 5281855 | CHEMBL6246 | Ellagic acid | inhibitor |