Gene name: HCRTR2
Protein name: Orexin receptor type
List of molecules and drugs that interact with protein O43614
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O43614_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 2 | O43614_7MA | 7MA | n/a | 9981404 | CHEMBL2385132 | N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide | n/a | |
| 3 | O43614_A6F | A6F | DB16962 | n/a | CHEMBL4650341 | methyl (2R,3S)-3-[(methanesulfonyl)amino]-2-({[(1s,4S)-4-phenylcyclohexyl]oxy}methyl)piperidine-1-carboxylate | n/a | |
| 4 | O43614_NH4 | NH4 | n/a | 223;16741146; | n/a | AMMONIUM ION | n/a | |
| 5 | O43614_NO3 | NO3 | DB14049 | 943 | CHEMBL186200 | NITRATE ION | n/a | |
| 6 | O43614_NRK | NRK | DB11951 | 56944144 | CHEMBL3545367 | (1~{R},2~{S})-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-~{N}-(5-fluoranylpyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide | antagonist | |
| 7 | O43614_NU8 | NU8 | n/a | 72707143 | CHEMBL3740099 | 2-(5,6-dimethoxypyridin-3-yl)-1,1-bis(oxidanylidene)-4-[[2,4,6-tris(fluoranyl)phenyl]methyl]pyrido[2,3-e][1,2,4]thiadiazin-3-one | n/a | |
| 8 | O43614_OLA | OLA | n/a | 445639 | CHEMBL8659 | OLEIC ACID | n/a | |
| 9 | O43614_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 10 | O43614_SUV | SUV | DB09034 | 24965990 | CHEMBL1083659 | [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone | antagonist | Ki(nM) = 0.35 IC50(nM) = 0.4 |
| 11 | O43614_NS2 | NS2 | DB15031 | 91801202 | CHEMBL4297590 | Daridorexant | antagonist |