Gene name: AKR1B10
Protein name: Aldo-keto reductase family
List of molecules and drugs that interact with protein O60218
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O60218_1WX | 1WX | n/a | 72836895 | n/a | {2-[(4-bromo-2,3,5,6-tetrafluorobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid | n/a | |
| 2 | O60218_388 | 388 | DB07028 | 16058629 | CHEMBL1230062 | (2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC ACID | n/a | IC50(nM) = 2700.0 |
| 3 | O60218_64I | 64I | n/a | 630263 | n/a | 2,2',3,3',5,5',6,6'-octafluorobiphenyl-4,4'-diol | n/a | |
| 4 | O60218_8QL | 8QL | n/a | 134812602 | n/a | (3S,6S,8S,9S,10R,13S,14R)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol | n/a | |
| 5 | O60218_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 6 | O60218_DQP | DQP | n/a | 122174240 | CHEMBL4092708 | {5-chloro-2-[(pentabromobenzyl)carbamoyl]phenoxy}acetic acid | n/a | |
| 7 | O60218_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 8 | O60218_EPR | EPR | n/a | n/a | n/a | {5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid | n/a | |
| 9 | O60218_F49 | F49 | n/a | 92044990 | n/a | [2,4-dioxo-3-(2,3,4,5-tetrabromo-6-methoxybenzyl)-3,4-dihydropyrimidin-1(2H)-yl]acetic acid | n/a | |
| 10 | O60218_FID | FID | DB02021 | 160024 | CHEMBL84446 | (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE | inhibitor | |
| 11 | O60218_FLF | FLF | DB02266 | 3371 | CHEMBL23588 | 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID | n/a | IC50(nM) = 760.0 |
| 12 | O60218_MK4 | MK4 | n/a | 121232443 | n/a | {5-chloro-2-[(2,4,6-tribromobenzyl)carbamoyl]phenoxy}acetic acid | n/a | |
| 13 | O60218_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 14 | O60218_NAP | NAP | DB03461 | 5885;57525501; | CHEMBL295069 | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | n/a | |
| 15 | O60218_QAP | QAP | n/a | 5281787 | CHEMBL319244 | 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate | n/a | |
| 16 | O60218_SBI | SBI | DB02712 | 337359 | CHEMBL266497 | SORBINIL | n/a | IC50(nM) = 9600.0 |
| 17 | O60218_UV8 | UV8 | n/a | n/a | n/a | 3-bromo-4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid | n/a | |
| 18 | O60218_W8X | W8X | n/a | 18468153 | CHEMBL4128992 | {2-[(4-bromobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid | n/a | |
| 19 | O60218_ZST | ZST | DB08772 | 1613 | CHEMBL10372 | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID | n/a | IC50(nM) = 620.0 |
| 20 | O60218_SUZ | SUZ | n/a | 16046677 | CHEMBL4525719 | [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid | n/a | |
| 21 | O60218_DB00605 | n/a | DB00605 | n/a | n/a | Sulindac | inhibitor | IC50(nM) = 2690.0 |
| 22 | O60218_TOL | TOL | DB02383 | 53359 | CHEMBL436 | Tolrestat | n/a | Ki(nM) = 50.0 IC50(nM) = 1.2 |
| 23 | O60218_SLO | SLO | DB06246 | 5472495 | CHEMBL488025 | Exisulind | inhibitor |