Gene name: PDE8A
Protein name: High affinity cAMP-specific
List of molecules and drugs that interact with protein O60658
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O60658_7XI | 7XI | n/a | 165416344 | n/a | 2-chloro-9-(3-(2,2-difluoroethoxy)benzyl)-9H-purin-6-amine | n/a | |
| 2 | O60658_7ZZ | 7ZZ | n/a | 165416346 | n/a | 2-chloro-9-(3-(2,2-difluoroethoxy)-5-(difluoromethoxy)benzyl)-9H-purin-6-amine | n/a | |
| 3 | O60658_807 | 807 | n/a | 165416347 | n/a | 2-chloro-9-(3-(2,2-difluoroethoxy)-5-isopropoxybenzyl)-9H-purin-6-amine | n/a | |
| 4 | O60658_80D | 80D | n/a | 165416348 | n/a | 2-chloro-9-(3-(2,2-difluoroethoxy)-5-(pyridin-4-yl)benzyl)-9H-purin-6-amine | n/a | |
| 5 | O60658_CFB | CFB | DB00631 | 119182 | CHEMBL1750 | 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE | n/a | |
| 6 | O60658_GJR | GJR | n/a | 156587313 | CHEMBL4757863 | 9-[[4-[2,2-bis(fluoranyl)ethoxy]pyridin-2-yl]methyl]-2-chloranyl-purin-6-amine | n/a | |
| 7 | O60658_GJU | GJU | n/a | 156587314 | CHEMBL4762103 | 9-[(1~{S})-1-[4-[2,2-bis(fluoranyl)ethoxy]pyridin-2-yl]ethyl]-2-chloranyl-purin-6-amine | n/a | |
| 8 | O60658_IBM | IBM | DB07954 | 3758 | CHEMBL275084 | 3-ISOBUTYL-1-METHYLXANTHINE | n/a | IC50(nM) = 700000.0 |
| 9 | O60658_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 10 | O60658_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a |