Gene name: HPGDS
Protein name: Hematopoietic prostaglandin D
List of molecules and drugs that interact with protein O60760
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O60760_0O4 | 0O4 | n/a | 57383478 | CHEMBL2035651 | 4-(isoquinolin-1-yl)-N-[2-(morpholin-4-yl)ethyl]benzamide | n/a | |
| 2 | O60760_0O5 | 0O5 | n/a | 56962332 | CHEMBL2035653 | 4-(3-methylisoquinolin-1-yl)-N-[2-(morpholin-4-yl)ethyl]benzamide | n/a | |
| 3 | O60760_7PQ | 7PQ | n/a | 56962331 | CHEMBL2035656 | 4-[2-(aminomethyl)naphthalen-1-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide | n/a | |
| 4 | O60760_93C | 93C | n/a | 134812607 | CHEMBL4238290 | N-[4-(2-oxopyrrolidin-1-yl)phenyl]-2-(pyridin-2-yl)pyrimidine-5-carboxamide | n/a | |
| 5 | O60760_9PQ | 9PQ | n/a | 60196237 | CHEMBL2035655 | 4-[2-(hydroxymethyl)naphthalen-1-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide | n/a | |
| 6 | O60760_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 7 | O60760_CBD | CBD | DB02633 | 172469;136700241; | CHEMBL572528 | CIBACRON BLUE | inhibitor | IC50(nM) = 200.0 |
| 8 | O60760_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 9 | O60760_CWC | CWC | n/a | 91799244 | CHEMBL3425950 | 4-(dimethylamino)-N-[5-(1H-indol-4-yl)pyridin-3-yl]butanamide | n/a | |
| 10 | O60760_D25 | D25 | DB07613 | 24764436 | CHEMBL265720 | 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole | n/a | IC50(nM) = 920.0 |
| 11 | O60760_D26 | D26 | DB07614 | 2763788 | CHEMBL261777 | PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE | n/a | IC50(nM) = 21.0 Kd(nM) = 51.0 EC50(nM) = 110.0 |
| 12 | O60760_D27 | D27 | DB07615 | 5282230 | CHEMBL415324 | 2-{[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino}benzoic acid | inhibitor | IC50(nM) = 11600.0 |
| 13 | O60760_D28 | D28 | DB07616 | 695906 | CHEMBL258467 | 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid | n/a | IC50(nM) = 138.0 |
| 14 | O60760_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 15 | O60760_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 16 | O60760_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 17 | O60760_GSF | GSF | DB04700 | 5326960 | n/a | L-GAMMA-GLUTAMYL-3-SULFINO-L-ALANYLGLYCINE | n/a | |
| 18 | O60760_GSH | GSH | DB00143 | 124886;25246407;171390563; | CHEMBL1543 | GLUTATHIONE | n/a | |
| 19 | O60760_HQL | HQL | DB07917 | 6540277 | CHEMBL574003 | 4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE | inhibitor | Ki(nM) = 5000.0 IC50(nM) = 1800.0 |
| 20 | O60760_KCD | KCD | n/a | n/a | CHEMBL4473072 | 7-(difluoromethoxy)-N-[trans-4-(2-hydroxypropan-2-yl)cyclohexyl]quinoline-3-carboxamide | n/a | |
| 21 | O60760_KRX | KRX | n/a | 59743926 | CHEMBL3425948 | 6-(3-methoxyphenyl)-N-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]pyridine-3-carboxamide | n/a | |
| 22 | O60760_KXO | KXO | n/a | 24991044 | CHEMBL1233897 | 6-(3-fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]pyridine-3-carboxamide | n/a | |
| 23 | O60760_M1W | M1W | n/a | 42571591 | CHEMBL3425952 | 3-(1H-indol-4-yl)-N-(3-methoxypropyl)-1,2,4-oxadiazole-5-carboxamide | n/a | |
| 24 | O60760_M4M | M4M | n/a | 3356666 | CHEMBL2163818 | 1-amino-9,10-dioxo-4-[(4-sulfamoylphenyl)amino]-9,10-dihydroanthracene-2-sulfonic acid | n/a | |
| 25 | O60760_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 26 | O60760_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 27 | O60760_NZO | NZO | DB08313 | 4122 | CHEMBL9514 | nocodazole | n/a | |
| 28 | O60760_O16 | O16 | DB01897 | 448998;5289059;5326847;6105620;45157700; | n/a | 3-(1,3-BENZOTHIAZOL-2-YL)-2-(1,4-DIOXO-1,2,3,4-TETRAHYDROPHTHALAZIN-6-YL)-5-[(E)-2-PHENYLVINYL]-3H-TETRAAZOL-2-IUM | n/a | |
| 29 | O60760_QPN | QPN | n/a | 156022397 | CHEMBL4853862 | 1-[1-(3-fluorophenyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-5-yl]propan-1-one | n/a | |
| 30 | O60760_TJG | TJG | n/a | n/a | CHEMBL5285108 | 7-cyclopropyl-N-[trans-4-(2-hydroxypropan-2-yl)cyclohexyl]-1,8-naphthyridine-3-carboxamide | n/a | |
| 31 | O60760_UX4 | UX4 | n/a | 92213413 | n/a | ethyl 4-[(8R)-3,8-dimethyl-4-oxo-4,6,7,8,9,10-hexahydrothieno[2',3':4,5]pyrimido[1,2-a]azepin-2-yl]carbamoylpiperazine-1-carboxylate | n/a | |
| 32 | O60760_VC3 | VC3 | DB08695 | 2737071 | CHEMBL264950 | 3-(4-nitrophenyl)-1H-pyrazole | n/a | |
| 33 | O60760_VH4 | VH4 | n/a | n/a | CHEMBL4852189 | 1-(3-fluorophenyl)-N-[trans-4-(2-hydroxypropan-2-yl)cyclohexyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide | n/a | |
| 34 | O60760_VH7 | VH7 | n/a | n/a | CHEMBL4864805 | N-[trans-4-(2-hydroxypropan-2-yl)cyclohexyl]-2-phenylimidazo[1,2-a]pyridine-6-carboxamide | n/a | |
| 35 | O60760_ZZA | ZZA | DB08790 | 121026 | CHEMBL406105 | 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID | n/a | IC50(nM) = 890000.0 Kd(nM) = 140000.0 |
| 36 | O60760_SWS | SWS | n/a | n/a | CHEMBL5279860 | 7-(azetidin-1-yl)-~{N}-[4-(2-oxidanylpropan-2-yl)cyclohexyl]-1,6-naphthyridine-3-carboxamide | n/a | |
| 37 | O60760_REA | REA | DB00755 | 444795 | CHEMBL38 | Tretinoin | n/a |