Gene name: KDM4A
Protein name: Lysine-specific demethylase 4A
List of molecules and drugs that interact with protein O75164
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O75164_08P | 08P | n/a | 56596552 | CHEMBL2030868 | N-(carboxycarbonyl)-D-cysteine | n/a | |
| 2 | O75164_0WS | 0WS | n/a | 57525825 | n/a | 2-(1H-pyrazol-3-yl)pyridine-4-carboxylic acid | n/a | |
| 3 | O75164_1KA | 1KA | n/a | 176960 | n/a | (2-hydroxyethoxy)acetaldehyde | n/a | |
| 4 | O75164_2HG | 2HG | n/a | 439391 | CHEMBL1614745 | (2R)-2-hydroxypentanedioic acid | n/a | |
| 5 | O75164_35M | 35M | n/a | 135567041 | CHEMBL3775262 | 2-[5-[(4-hydroxyphenyl)carbonylamino]-2-oxidanyl-phenyl]pyridine-4-carboxylic acid | n/a | |
| 6 | O75164_5TZ | 5TZ | n/a | 96607511 | CHEMBL3774692 | 2-(2-azanyl-1,3-thiazol-4-yl)pyridine-4-carboxylic acid | n/a | |
| 7 | O75164_5U8 | 5U8 | n/a | 112499936;135567108; | CHEMBL3774747 | 8-[4-[2-[(4-fluorophenyl)methyl-methyl-amino]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 8 | O75164_5UB | 5UB | n/a | 112499935;135567107; | CHEMBL3775636 | 8-(1,3-thiazol-4-yl)-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 9 | O75164_5UJ | 5UJ | n/a | 112499943;135567115; | CHEMBL3775894 | 8-[4-[2-[4-[3,5-bis(chloranyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 10 | O75164_5UL | 5UL | n/a | 112499940;135567112; | CHEMBL3775899 | 8-[4-[2-[4-[(4-chlorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 11 | O75164_5UO | 5UO | n/a | 112499938;135567110; | CHEMBL3775977 | 8-[4-[2-[4-(4-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 12 | O75164_5UP | 5UP | n/a | 112499933 | CHEMBL3775782 | 2-(2-azanyl-1,3-thiazol-4-yl)pyridine-4-carboxamide | n/a | |
| 13 | O75164_5V1 | 5V1 | n/a | 84153874 | CHEMBL3775995 | 2-[[(phenylmethyl)amino]methyl]pyridine-4-carboxylic acid | n/a | |
| 14 | O75164_5V7 | 5V7 | n/a | 112499934;135567105; | CHEMBL3774798 | 8-(2-azanyl-1,3-thiazol-4-yl)-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 15 | O75164_5YQ | 5YQ | n/a | 56867110 | n/a | 2-{2-[(pyridin-3-ylmethyl)amino]pyrimidin-4-yl}pyridine-4-carboxylic acid | n/a | |
| 16 | O75164_6Z1 | 6Z1 | n/a | 135567038 | CHEMBL3775867 | 2-[5-[(5-methyl-1,2-oxazol-3-yl)carbonylamino]-2-oxidanyl-phenyl]pyridine-4-carboxylic acid | n/a | |
| 17 | O75164_7WH | 7WH | n/a | 135567037 | CHEMBL3775380 | 2-[5-(2-methoxyethanoylamino)-2-oxidanyl-phenyl]pyridine-4-carboxylic acid | n/a | |
| 18 | O75164_8HQ | 8HQ | n/a | 97394 | CHEMBL1435274 | 8-hydroxyquinoline-4-carboxylic acid | n/a | |
| 19 | O75164_8XQ | 8XQ | n/a | 459617 | CHEMBL1230640 | 8-hydroxyquinoline-5-carboxylic acid | n/a | |
| 20 | O75164_92Y | 92Y | n/a | 132472249 | CHEMBL5181544 | (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol | n/a | |
| 21 | O75164_9CJ | 9CJ | n/a | 135567042 | CHEMBL3775272 | 2-[5-[2-(3-methoxyphenyl)ethanoylamino]-2-oxidanyl-phenyl]pyridine-4-carboxylic acid | n/a | |
| 22 | O75164_9DJ | 9DJ | n/a | 118598059 | CHEMBL4216044 | 3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid | n/a | |
| 23 | O75164_9FJ | 9FJ | n/a | 90253505 | CHEMBL4211946 | 3-({[(1R)-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl]methyl}amino)pyridine-4-carboxylic acid | n/a | |
| 24 | O75164_AKG | AKG | DB08845 | 51;156274072; | CHEMBL1686 | 2-OXOGLUTARIC ACID | n/a | |
| 25 | O75164_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 26 | O75164_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 27 | O75164_DHB | DHB | DB03946 | 72 | CHEMBL37537 | 3,4-DIHYDROXYBENZOIC ACID | n/a | |
| 28 | O75164_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 29 | O75164_DZA | DZA | n/a | 15331;72200802; | CHEMBL2164243 | DAMINOZIDE | n/a | |
| 30 | O75164_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 31 | O75164_ENZ | ENZ | n/a | n/a | n/a | (4~{R})-5-methyl-4-phenyl-2-pyridin-2-yl-pyrazolidin-3-one | n/a | |
| 32 | O75164_FE2 | FE2 | n/a | 27284 | n/a | FE (II) ION | n/a | |
| 33 | O75164_FNQ | FNQ | n/a | 138753208 | CHEMBL4559561 | 8-[4-[2-[4-(4-pyridin-3-ylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 34 | O75164_FO2 | FO2 | n/a | 138393333 | CHEMBL4483780 | 8-[4-(1-methylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 35 | O75164_FO8 | FO8 | n/a | 138753209 | CHEMBL4466130 | 8-[4-[2-[4-[4-(2-morpholin-4-ylethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 36 | O75164_FOW | FOW | n/a | 138393336 | CHEMBL4449500 | 8-[4-(2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylethyl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 37 | O75164_FQ5 | FQ5 | n/a | 127032023;137175094; | CHEMBL3774537 | 8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 38 | O75164_FQB | FQB | n/a | 138393334 | CHEMBL4585876 | 8-[4-[2-[4-[4-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 39 | O75164_FQE | FQE | n/a | 138753211 | CHEMBL4438830 | 8-[4-[2-[4-[3-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 40 | O75164_FQH | FQH | n/a | 127032361;137175122; | CHEMBL3775548 | 8-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 41 | O75164_FQN | FQN | n/a | 138393339 | CHEMBL4529932 | 8-[4-(1-cyclopentylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 42 | O75164_FQQ | FQQ | n/a | 138393341 | CHEMBL4573390 | 8-[4-[2-[4-(3-chlorophenyl)-4-methyl-piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 43 | O75164_FUM | FUM | DB01677 | 444972;21883788; | CHEMBL503160 | FUMARIC ACID | n/a | |
| 44 | O75164_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 45 | O75164_HQ2 | HQ2 | n/a | 44887551 | CHEMBL1315670 | 8-hydroxy-3-(piperazin-1-yl)quinoline-5-carboxylic acid | n/a | |
| 46 | O75164_KC6 | KC6 | n/a | 45377880;72200351; | CHEMBL1615036 | 4'-[(2-aminoethyl)carbamoyl]-2,2'-bipyridine-4-carboxylic acid | n/a | |
| 47 | O75164_KCH | KCH | n/a | 135567039 | CHEMBL3775869 | 2-(5-azanyl-2-oxidanyl-phenyl)pyridine-4-carboxylic acid | n/a | |
| 48 | O75164_LEL | LEL | n/a | 91801131 | CHEMBL3621851 | 2-(2H-1,2,3-triazol-4-yl)pyridine-4-carboxylic acid | n/a | |
| 49 | O75164_MMK | MMK | n/a | 137349755 | n/a | 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid | n/a | |
| 50 | O75164_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 51 | O75164_MY7 | MY7 | n/a | n/a | n/a | 2-(3-methyl-5-oxidanylidene-4-phenyl-4~{H}-pyrazol-1-yl)-3~{H}-benzimidazole-5-carboxylic acid | n/a | |
| 52 | O75164_N5J | N5J | n/a | 590102;135567106; | CHEMBL3770256 | 3H-pyrido[3,4-d]pyrimidin-4-one | n/a | |
| 53 | O75164_N81 | N81 | DB01727 | 447805 | n/a | 3-carboxy-2,3-dideoxy-D-erythro-pentaric acid | n/a | |
| 54 | O75164_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 55 | O75164_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 56 | O75164_OGA | OGA | n/a | 3080614 | CHEMBL90852 | N-OXALYLGLYCINE | n/a | |
| 57 | O75164_OXY | OXY | DB09140 | 977 | CHEMBL1234886 | OXYGEN MOLECULE | n/a | |
| 58 | O75164_PD2 | PD2 | n/a | 10365 | CHEMBL316034 | PYRIDINE-2,4-DICARBOXYLIC ACID | n/a | |
| 59 | O75164_PPI | PPI | DB03766 | 1032 | CHEMBL14021 | PROPANOIC ACID | n/a | |
| 60 | O75164_PYR | PYR | DB00119 | 1060 | CHEMBL1162144 | PYRUVIC ACID | n/a | |
| 61 | O75164_QC1 | QC1 | n/a | 81750967 | n/a | 3-{[(4-fluorophenyl)methyl]amino}pyridine-4-carboxylic acid | n/a | |
| 62 | O75164_QC2 | QC2 | n/a | 76901620 | CHEMBL4228384 | 2-[5-(3-hydroxyphenyl)-1H-pyrazol-1-yl]pyridine-4-carboxylic acid | n/a | |
| 63 | O75164_S2G | S2G | n/a | 439939 | CHEMBL1615211 | (2S)-2-HYDROXYPENTANEDIOIC ACID | n/a | |
| 64 | O75164_S2X | S2X | n/a | 135567040 | CHEMBL3774598 | 2-(5-acetamido-2-oxidanyl-phenyl)pyridine-4-carboxylic acid | n/a | |
| 65 | O75164_SIN | SIN | DB00139 | 1110;21952380; | CHEMBL576 | SUCCINIC ACID | n/a | |
| 66 | O75164_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 67 | O75164_VAO | VAO | n/a | 135567036 | CHEMBL3774693 | 2-(5-cyano-2-oxidanyl-phenyl)pyridine-4-carboxylic acid | n/a | |
| 68 | O75164_Y28 | Y28 | n/a | 44820611 | CHEMBL591689 | O-benzyl-N-(carboxycarbonyl)-D-tyrosine | n/a | |
| 69 | O75164_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 70 | O75164_SRT | SRT | DB14756 | 447315 | CHEMBL225983 | S,R MESO-TARTARIC ACID | n/a |