O76290 O76290_TRYBB
Gene name: PTR1
Protein name: Pteridine reductase

List of molecules and drugs that interact with protein O76290

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	O76290_1CY	1CY	DB14763	9049	CHEMBL747	1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine	n/a
2	O76290_3KH	3KH	n/a	50994745	CHEMBL1650282	5-(1H-benzotriazol-6-yl)-1,3,4-thiadiazol-2-amine	n/a
3	O76290_3KN	3KN	n/a	50925635	CHEMBL1650277	3-(5-amino-1,3,4-thiadiazol-2-yl)pyridin-4-amine	n/a
4	O76290_4NR	4NR	n/a	86580352	CHEMBL3318802	5-(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
5	O76290_6F4	6F4	n/a	6917216	n/a	N~2~-[(thiophen-2-yl)methyl]-1,3,4-thiadiazole-2,5-diamine	n/a
6	O76290_6JM	6JM	n/a	667581	CHEMBL1224325	2-(3,4-dihydroxyphenyl)-3,6-dihydroxy-4H-1-benzopyran-4-one	n/a
7	O76290_6JO	6JO	n/a	688803	CHEMBL4464764	3,6-dihydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-one	n/a
8	O76290_6JP	6JP	DB01094	72281	CHEMBL399121	(2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one	n/a
9	O76290_6KT	6KT	n/a	606347	CHEMBL5271824	2-amino-1,3-benzothiazole-6-carboxamide	n/a
10	O76290_6QT	6QT	n/a	124222415	n/a	(2~{R})-2-(3-hydroxyphenyl)-6-oxidanyl-2,3-dihydrochromen-4-one	n/a
11	O76290_ACT	ACT	DB14511	175	n/a	ACETATE ION	n/a
12	O76290_AOB	AOB	n/a	86580354;135566677;	CHEMBL3318208	(E)-2-amino-4-oxo-6-styryl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile	n/a
13	O76290_AX3	AX3	n/a	47866	CHEMBL1231107	N~2~-cyclopropyl-1,3,5-triazine-2,4,6-triamine	n/a
14	O76290_AX4	AX4	n/a	11096469	CHEMBL578789	6-[(4-methylphenyl)sulfanyl]pyrimidine-2,4-diamine	n/a
15	O76290_AX5	AX5	n/a	235894	CHEMBL566948	6-(benzylsulfanyl)pyrimidine-2,4-diamine	n/a
16	O76290_AX7	AX7	n/a	13624	CHEMBL305513	1H-benzimidazol-2-amine	n/a
17	O76290_AX8	AX8	n/a	887666	CHEMBL520667	1-(3,4-dichlorobenzyl)-1H-benzimidazol-2-amine	n/a
18	O76290_CC6	CC6	n/a	5281610	CHEMBL503168	3,5,7-trihydroxy-2-(2-hydroxyphenyl)-4H-1-benzopyran-4-one	n/a
19	O76290_CL	CL	n/a	312	n/a	CHLORIDE ION	n/a
20	O76290_CP6	CP6	DB00205	4993	CHEMBL36	5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE	n/a
21	O76290_D1D	D1D	DB02693	445528	n/a	(4S,5S)-1,2-DITHIANE-4,5-DIOL	n/a
22	O76290_D64	D64	n/a	44201362	n/a	6-(4-methylphenyl)quinazoline-2,4-diamine	n/a
23	O76290_DMS	DMS	DB01093	679	CHEMBL504	DIMETHYL SULFOXIDE	n/a
24	O76290_DTD	DTD	DB01822	439407	n/a	DITHIANE DIOL	n/a
25	O76290_DTT	DTT	DB04447	439196	CHEMBL406270	2,3-DIHYDROXY-1,4-DITHIOBUTANE	n/a
26	O76290_DTU	DTU	DB01692	439352	CHEMBL1232391	(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL	n/a
27	O76290_EDO	EDO	n/a	174	CHEMBL457299	1,2-ETHANEDIOL	n/a
28	O76290_EUB	EUB	n/a	137628304	CHEMBL4468228	4-[(2-azanyl-1,3-benzothiazol-6-yl)oxymethyl]benzenecarbonitrile	n/a
29	O76290_EUE	EUE	n/a	87152	CHEMBL432942	6-methylsulfonyl-1,3-benzothiazol-2-amine	n/a
30	O76290_EUH	EUH	n/a	2735964	CHEMBL95463	6-(trifluoromethylsulfanyl)-1,3-benzothiazol-2-amine	n/a
31	O76290_EUK	EUK	n/a	137628305	CHEMBL4439011	6-[(3,4-dichlorophenyl)methylsulfanyl]-1,3-benzothiazol-2-amine	n/a
32	O76290_EV8	EV8	n/a	137628306	CHEMBL4452155	methyl 1-[4-[[(2-azanyl-1,3-benzothiazol-6-yl)carbonylamino]methyl]phenyl]carbonylpiperidine-4-carboxylate	n/a
33	O76290_EVW	EVW	n/a	137628310	CHEMBL4435791	2-azanyl-~{N}-(diphenylmethyl)-1,3-benzothiazole-6-carboxamide	n/a
34	O76290_EVZ	EVZ	n/a	137628309	CHEMBL4441552	methyl 1-[4-[(2-azanyl-1,3-benzothiazol-6-yl)sulfanylmethyl]phenyl]carbonylpiperidine-4-carboxylate	n/a
35	O76290_EWK	EWK	n/a	137628311	CHEMBL4562350	4-[(2-azanyl-1,3-benzothiazol-6-yl)sulfanylmethyl]-~{N}-(phenylmethyl)benzamide	n/a
36	O76290_EWT	EWT	n/a	137628312	CHEMBL4458858	2-azanyl-~{N}-[(3,4-dichlorophenyl)methyl]-1,3-benzothiazole-6-carboxamide	n/a
37	O76290_FDB	FDB	n/a	596364;135520243;	CHEMBL3318499	2-amino-5-methyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one	n/a
38	O76290_FE1	FE1	DB07765	23629645	CHEMBL1232702	METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE	n/a
39	O76290_FOL	FOL	DB00158	6037;5280354;135398658;	CHEMBL1622	FOLIC ACID	n/a
40	O76290_FQW	FQW	n/a	86580364;135566680;	CHEMBL3318816	2-amino-5-phenethyl-6-phenyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one	n/a
41	O76290_GFE	GFE	n/a	25889	CHEMBL92583	1-(3,4-dichlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine	n/a
42	O76290_GJQ	GJQ	n/a	138115379	n/a	(2~{R})-1-(3,4-dichlorophenyl)-2-(4-nitrophenyl)-2~{H}-1,3,5-triazine-4,6-diamine	n/a
43	O76290_GOL	GOL	DB09462	753	CHEMBL692	GLYCEROL	n/a
44	O76290_H0V	H0V	n/a	86580355	CHEMBL3318804	5-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
45	O76290_IQW	IQW	n/a	86580351	CHEMBL3318801	5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
46	O76290_IZ9	IZ9	n/a	86580356	CHEMBL3318214	(E)-2,4-diamino-6-(4-methylstyryl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile	n/a
47	O76290_JR2	JR2	n/a	71138081	CHEMBL3318486	4-(pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine	n/a
48	O76290_JUO	JUO	n/a	86580347	CHEMBL3318491	2-amino-4-thiomorpholino-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile	n/a
49	O76290_KM5	KM5	n/a	146675127	CHEMBL5180552	methyl 1-[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-ethyl-amino]phenyl]carbonylpiperidine-4-carboxylate	n/a
50	O76290_KMK	KMK	n/a	146675128	CHEMBL5171609	methyl 1-[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-(3-oxidanylpropyl)amino]phenyl]carbonylpiperidine-4-carboxylate	n/a
51	O76290_KP2	KP2	n/a	10537176	CHEMBL3318803	5-phenyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
52	O76290_KTZ	KTZ	n/a	86580360	CHEMBL3318920	N4,N4-dimethyl-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
53	O76290_LYA	LYA	DB00642	446556;5288715;135410875;	CHEMBL225072	2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID	n/a
54	O76290_M2N	M2N	n/a	15761739	CHEMBL3318820	5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
55	O76290_M4V	M4V	n/a	86580362;135566679;	CHEMBL3318815	2-amino-6-(4-bromophenyl)-5-phenyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one	n/a
56	O76290_MCV	MCV	n/a	457378	CHEMBL107023	5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]pyrimidine-2,4-diamine	n/a
57	O76290_MTX	MTX	DB00563	126941	CHEMBL34259	METHOTREXATE	n/a
58	O76290_N0Z	N0Z	n/a	21589971	n/a	2,4-bis(azanyl)-9~{H}-pyrimido[4,5-b]indol-6-ol	n/a
59	O76290_NA	NA	n/a	923	n/a	SODIUM ION	n/a
60	O76290_NAP	NAP	DB03461	5885;57525501;	CHEMBL295069	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	n/a
61	O76290_NDP	NDP	DB02338	5884;134821689;	CHEMBL407009	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	n/a
62	O76290_NI	NI	n/a	934	n/a	NICKEL (II) ION	n/a
63	O76290_NWJ	NWJ	n/a	118708947	CHEMBL3318494	2-amino-6-(3-formylphenyl)-4-(pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile	n/a
64	O76290_OZJ	OZJ	n/a	118708722	CHEMBL3318211	2,4-diamino-6-(3-formylphenyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile	n/a
65	O76290_Q0K	Q0K	n/a	86580350;135566676;	CHEMBL3318496	2-amino-5-(p-tolyl)-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one	n/a
66	O76290_TMQ	TMQ	DB01157	5582;59961053;	n/a	TRIMETREXATE	n/a
67	O76290_UEN	UEN	n/a	86580358	CHEMBL3318806	N4-cyclohexyl-5-(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
68	O76290_UHX	UHX	n/a	86580361	CHEMBL3318911	6-(4-fluorophenyl)-5-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
69	O76290_UIH	UIH	n/a	86580363	CHEMBL3318913	6-(4-bromophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
70	O76290_VGD	VGD	n/a	21527	CHEMBL269158	6-chloro-1H-benzimidazol-2-amine	n/a
71	O76290_VGF	VGF	n/a	42627579	CHEMBL484995	1-(3,4-DICHLOROBENZYL)-7-PHENYL-1H-BENZIMIDAZOL-2-AMINE	n/a
72	O76290_VS8	VS8	n/a	86580359	CHEMBL3318922	N4-cyclohexyl-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	n/a
73	O76290_W8G	W8G	n/a	86580348	CHEMBL3318487	4-thiomorpholino-7H-pyrrolo[2,3-d]pyrimidin-2-amine	n/a
74	O76290_WHF	WHF	n/a	50994805	CHEMBL1650287	3-(5-AMINO-1,3,4-THIADIAZOL-2-YL)-1-THIOPHEN-2-YLPROPAN-1-ONE	n/a
75	O76290_XP0	XP0	n/a	86580349	CHEMBL3318495	5-(phenylethynyl)-4-(pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine	n/a
76	O76290_YGL	YGL	n/a	86580357;135566678;	CHEMBL3318808	2-amino-5,6-diphenyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one	n/a