Gene name: STK10
Protein name: Serine/threonine-protein kinase 10
List of molecules and drugs that interact with protein O94804
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O94804_1N1 | 1N1 | DB01254 | 3062316 | CHEMBL1421 | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | n/a | Kd(nM) = 1200.0 |
| 2 | O94804_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 3 | O94804_274 | 274 | n/a | 9549297 | CHEMBL261641 | (3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-1H-PYRROL-2-YL}METHYLENE)-N-METHYL-2-OXOINDOLINE-5-SULFONAMIDE | n/a | |
| 4 | O94804_38O | 38O | DB05928 | 135398510 | CHEMBL522892 | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one | n/a | |
| 5 | O94804_88Z | 88Z | DB12307 | 42642645 | CHEMBL1230609 | N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | n/a | |
| 6 | O94804_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 7 | O94804_B6E | B6E | n/a | 10230568 | CHEMBL244297 | ~{N}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{H}-benzimidazol-2-yl]furan-2-carboxamide | n/a | |
| 8 | O94804_B96 | B96 | DB03044 | 156422 | CHEMBL103667 | 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA | n/a | IC50(nM) = 1000.0 Kd(nM) = 7.1 |
| 9 | O94804_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 10 | O94804_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 11 | O94804_DB8 | DB8 | DB06616 | 5328940 | CHEMBL288441 | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | n/a | IC50(nM) = 52.0 Kd(nM) = 7.0 |
| 12 | O94804_DJ8 | DJ8 | n/a | 162421353 | n/a | 1-[(4-chloranyl-2-methyl-phenyl)methyl]-3-(7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.1^{2,6}.0^{17,20}]docosa-1(20),2(22),3,5,14(21),15,18-heptaen-5-yl)urea | n/a | |
| 13 | O94804_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 14 | O94804_G6I | G6I | n/a | 66557867 | n/a | N-{3-[(3-{4-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}pyridin-2-yl)amino]-4-methylphenyl}-3-(trifluoromethyl)benzamide | n/a | |
| 15 | O94804_GW8 | GW8 | n/a | 56932129 | CHEMBL5395335 | 1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea | n/a | |
| 16 | O94804_R09 | R09 | n/a | 44433173 | CHEMBL237571 | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl}pyridine | n/a | |
| 17 | O94804_R70 | R70 | n/a | 134822023 | CHEMBL4876254 | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | n/a | |
| 18 | O94804_XZN | XZN | n/a | 60202320 | CHEMBL4067978 | 4-[(3,5-DICHLORO-4-METHOXYPHENYL)AMINO]-6-METHOXY-7-[3-(4-METHYLPIPERAZIN-1-YL)PROPOXY]QUINOLINE-3-CARBONITRILE | n/a | |
| 19 | O94804_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |