Gene name: GLS
Protein name: Glutaminase kidney isoform,
List of molecules and drugs that interact with protein O94925
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O94925_04A | 04A | n/a | 3372016 | CHEMBL2177757 | N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) | n/a | |
| 2 | O94925_5XX | 5XX | n/a | 118988615 | CHEMBL3770355 | 2-phenyl-~{N}-[5-[[(3~{R})-1-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide | n/a | |
| 3 | O94925_5XY | 5XY | n/a | 118988616 | CHEMBL3771098 | 2-phenyl-~{N}-[5-[[(3~{S})-1-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide | n/a | |
| 4 | O94925_5XZ | 5XZ | n/a | 118988617 | CHEMBL3769593 | 2-phenyl-~{N}-[5-[(3~{S})-3-[[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]ethanamide | n/a | |
| 5 | O94925_63J | 63J | DB15232 | 71577426 | CHEMBL3639788 | 2-(pyridin-2-yl)-N-(5-{4-[6-({[3-(trifluoromethoxy)phenyl]acetyl}amino)pyridazin-3-yl]butyl}-1,3,4-thiadiazol-2-yl)acetamide | modulator | |
| 6 | O94925_69V | 69V | n/a | 118988623 | CHEMBL3770889 | 2-phenyl-N-{5-[4-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide | n/a | |
| 7 | O94925_B4A | B4A | n/a | 121256411 | CHEMBL3770617 | 2-phenyl-N-{5-[4-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}amino)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide | n/a | |
| 8 | O94925_BP0 | BP0 | n/a | 404513 | CHEMBL2177758 | 5,5'-(sulfanediyldiethane-2,1-diyl)bis(1,3,4-thiadiazol-2-amine) | n/a | |
| 9 | O94925_BP8 | BP8 | n/a | 2247525 | CHEMBL1704892 | 5,5'-pentane-1,5-diylbis(1,3,4-thiadiazol-2-amine) | n/a | |
| 10 | O94925_BP9 | BP9 | n/a | 57406212 | n/a | 5,5'-butane-1,4-diylbis(1,3,4-thiadiazol-2-amine) | n/a | |
| 11 | O94925_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 12 | O94925_EN3 | EN3 | n/a | 155294431 | CHEMBL4849357 | (E)-15,22-Dioxa-4,11-diaza-5(2,5)-thiadiazola-10(3,6)-pyridazina-1,14(1,3)-dibenzenacyclodocosaphan-18-ene-3,12-dione | n/a | |
| 13 | O94925_GLN | GLN | DB00130 | 5961;6992086; | CHEMBL930 | GLUTAMINE | n/a | |
| 14 | O94925_GLU | GLU | DB00142 | 33032;44272391;88747398; | CHEMBL575060 | GLUTAMIC ACID | n/a | |
| 15 | O94925_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 16 | O94925_HZO | HZO | n/a | 10468639 | n/a | 2,2-dimethyl-1,3-dihydrobenzo[a]phenanthridin-4-one | n/a | |
| 17 | O94925_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 18 | O94925_ONL | ONL | DB04296 | 5289072;28125464; | n/a | 5-OXO-L-NORLEUCINE | n/a | |
| 19 | O94925_Q94 | Q94 | n/a | 121256446 | CHEMBL3769558 | N-{5-[(3R)-3-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]amino}pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide | n/a | |
| 20 | O94925_Q9A | Q9A | n/a | 121256441 | CHEMBL3770033 | N-{5-[(3S)-3-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]amino}pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide | n/a | |
| 21 | O94925_Q9M | Q9M | n/a | 121256374 | CHEMBL3769936 | 2-phenyl-N-{5-[(1-{5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}azetidin-3-yl)oxy]-1,3,4-thiadiazol-2-yl}acetamide | n/a | |
| 22 | O94925_Q9S | Q9S | n/a | 121256372 | n/a | 5-{4-[(5-amino-1,3,4-thiadiazol-2-yl)oxy]piperidin-1-yl}-1,3,4-thiadiazol-2-amine | n/a | |
| 23 | O94925_Q9V | Q9V | n/a | 121256386 | CHEMBL3771046 | N-[5-(4-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]oxy}piperidin-1-yl)-1,3,4-thiadiazol-2-yl]acetamide | n/a | |
| 24 | O94925_QA4 | QA4 | n/a | 121256435 | CHEMBL3769897 | 2-cyclopropyl-N-{5-[4-({5-[(cyclopropylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide | n/a | |
| 25 | O94925_QAA | QAA | n/a | 121256316 | CHEMBL3770102 | 2-phenyl-N-{6-[4-({6-[(phenylacetyl)amino]pyridazin-3-yl}oxy)piperidin-1-yl]pyridazin-3-yl}acetamide | n/a | |
| 26 | O94925_QAJ | QAJ | n/a | 121256429 | n/a | 2-(pyridin-3-yl)-N-(5-{4-[(5-{[(pyridin-3-yl)acetyl]amino}-1,3,4-thiadiazol-2-yl)amino]piperidin-1-yl}-1,3,4-thiadiazol-2-yl)acetamide | n/a | |
| 27 | O94925_QAM | QAM | n/a | 121256344 | CHEMBL3769551 | N-(5-{[1-(5-amino-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy}-1,3,4-thiadiazol-2-yl)-2-phenylacetamide | n/a | |
| 28 | O94925_R0C | R0C | n/a | 100951644 | CHEMBL4437106 | (2~{S})-2-methoxy-2-phenyl-~{N}-[5-[[(3~{R})-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide | n/a | |
| 29 | O94925_R90 | R90 | n/a | 155512936 | CHEMBL4438255 | ~{N}-[5-[[(3~{R})-1-(5-azanyl-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]-2-phenyl-ethanamide | n/a | |
| 30 | O94925_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 31 | O94925_U27 | U27 | n/a | 121256367 | CHEMBL3769701 | 2-phenyl-N-{5-[(3R)-3-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide | n/a | |
| 32 | O94925_V4I | V4I | n/a | 168654825 | CHEMBL5420669 | 3-[2-oxidanylidene-2-[[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]amino]ethyl]benzoic acid | n/a | |
| 33 | O94925_V59 | V59 | n/a | 168654826 | CHEMBL5398770 | 2-(3-phenoxyphenyl)-N-[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide | n/a | |
| 34 | O94925_ZBS | ZBS | n/a | 74223468 | CHEMBL4466771 | 2-phenyl-~{N}-[5-[(1~{S},3~{S})-3-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]cyclohexyl]-1,3,4-thiadiazol-2-yl]ethanamide | n/a | |
| 35 | O94925_GGL | GGL | DB00142 | 33032;44272391;88747398; | CHEMBL575060 | Glutamic acid | n/a |