Gene name: CHEK2
Protein name: Serine/threonine-protein kinase Chk2
List of molecules and drugs that interact with protein O96017
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O96017_A9T | A9T | n/a | 11518511 | CHEMBL251170 | 2-(4-{[1-(4-CHLOROBENZYL)PIPERIDIN-4-YL]METHOXY}PHENYL)-1H-BENZIMIDAZOLE-5-CARBOXAMIDE | n/a | |
| 2 | O96017_A9U | A9U | n/a | 11524997 | CHEMBL249959 | 2-{4-[(1-BENZYLPIPERIDIN-4-YL)METHOXY]PHENYL}-1H-BENZIMIDAZOLE-6-CARBOXAMIDE | n/a | |
| 3 | O96017_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 4 | O96017_B4W | B4W | n/a | 135566381 | CHEMBL1231179 | 2-{4-[(3S)-PYRROLIDIN-3-YLAMINO]QUINAZOLIN-2-YL}PHENOL | n/a | |
| 5 | O96017_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 6 | O96017_CWS | CWS | n/a | 12362244 | n/a | 6-METHYLQUINAZOLIN-4-AMINE | n/a | |
| 7 | O96017_D1A | D1A | n/a | 25110843 | n/a | N-[4-[(E)-N-carbamimidamido-C-methyl-carbonimidoyl]phenyl]-7-nitro-1H-indole-2-carboxamide | n/a | |
| 8 | O96017_DBQ | DBQ | DB04367 | 5288032;135451156; | CHEMBL255465 | DEBROMOHYMENIALDISINE | inhibitor | |
| 9 | O96017_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 10 | O96017_H3R | H3R | n/a | 18774 | CHEMBL1411986 | 5-METHYL-3-PHENYL-1H-PYRAZOLE | n/a | |
| 11 | O96017_HAU | HAU | n/a | 6469269 | n/a | 1-acetyl-N-(5-methylpyridin-2-yl)piperidine-4-carboxamide | n/a | |
| 12 | O96017_HCW | HCW | n/a | 57547747 | n/a | 1,3-BIS{4-[(1E)-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)ETHANEHYDRAZONOYL]PHENYL}UREA | n/a | |
| 13 | O96017_LWH | LWH | n/a | 135566382 | CHEMBL1234108 | 4-(1H-pyrazol-5-yl)-2-{4-[(3S)-pyrrolidin-3-ylamino]quinazolin-2-yl}phenol | n/a | |
| 14 | O96017_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 15 | O96017_NO3 | NO3 | DB14049 | 943 | CHEMBL186200 | NITRATE ION | n/a | |
| 16 | O96017_NXP | NXP | n/a | 25129353 | n/a | N-{4-[(1E)-N-CARBAMIMIDOYLETHANEHYDRAZONOYL]PHENYL}-1H-INDOLE-3-CARBOXAMIDE | n/a | |
| 17 | O96017_ODH | ODH | n/a | 2978966 | CHEMBL1408855 | N-(furan-2-ylmethyl)quinoxaline-6-carboxamide | n/a | |
| 18 | O96017_ODO | ODO | n/a | 135399628 | n/a | 4-[(E)-C-methyl-N-oxidanyl-carbonimidoyl]benzene-1,3-diol | n/a | |
| 19 | O96017_P3J | P3J | n/a | 7446899 | n/a | 3-(PYRIDIN-3-YL)-1H-PYRAZOL-5-AMINE | n/a | |
| 20 | O96017_RQQ | RQQ | n/a | 654229 | CHEMBL1456597 | N-[(4-methoxyphenyl)methyl]quinoxaline-6-carboxamide | n/a | |
| 21 | O96017_RU5 | RU5 | n/a | 9969021 | CHEMBL179583 | 2-[4-(4-CHLOROPHENOXY)PHENYL]-1H-BENZIMIDAZOLE-6-CARBOXAMIDE | n/a | |
| 22 | O96017_RU9 | RU9 | n/a | 11371378 | CHEMBL367263 | 2-(4-(3-HYDROXYPHENOXY)PHENYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXAMIDE | n/a | |
| 23 | O96017_UPX | UPX | n/a | 72199642 | n/a | N-{4-[(1E)-N-1H-IMIDAZOL-2-YLETHANEHYDRAZONOYL]PHENYL}-7-NITRO-1H-INDOLE-2-CARBOXAMIDE | n/a | |
| 24 | O96017_VFB | VFB | n/a | 137350121;163999276; | n/a | 3,4-dihydro[1,2,4]triazolo[1,5-a][3,1]benzimidazol-9-ium | n/a | |
| 25 | O96017_VGM | VGM | n/a | 44520782 | CHEMBL600441 | 4-[2-AMINO-5-(4-HYDROXY-3-METHOXYPHENYL)PYRIDIN-3-YL]BENZAMIDE | n/a | |
| 26 | O96017_WVI | WVI | n/a | 3815550 | n/a | 3-METHYL-4-(THIOPHEN-2-YL)-1H-PYRAZOL-5-AMINE | n/a | |
| 27 | O96017_XBJ | XBJ | n/a | 135564841 | CHEMBL1236782 | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL | n/a | |
| 28 | O96017_YCF | YCF | n/a | 57547743;137350186;172936270; | n/a | (2E)-N-hydroxy-2-[1-(4-{[(4-{(1E)-1-[2-(N'-hydroxycarbamimidoyl)hydrazinylidene]ethyl}phenyl)carbamoyl]amino}phenyl)ethylidene]hydrazinecarboximidamide | n/a | |
| 29 | O96017_YIQ | YIQ | n/a | 57547724 | n/a | (E)-5-(1-(2-CARBAMIMIDOYLHYDRAZONO)ETHYL)-N-(1H-INDOL-6-YL)-1H-INDOLE-2-CARBOXAMIDE | n/a | |
| 30 | O96017_YIR | YIR | n/a | 57547794 | n/a | (E)-N-(5-(2-CARBAMIMIDOYLHYDRAZONO)-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)-7-NITRO-1H-INDOLE-2-CARBOXAMIDE | n/a | |
| 31 | O96017_YIT | YIT | n/a | 25130404 | n/a | N-{4-[(1E)-N-carbamimidoylbutanehydrazonoyl]phenyl}-5-methoxy-1H-indole-2-carboxamide | n/a | |
| 32 | O96017_Z0O | Z0O | n/a | 1350527 | CHEMBL1490765 | 1-(TERT-BUTYL)-3-(QUINOXALIN-6-YL)UREA | n/a | |
| 33 | O96017_Z2M | Z2M | n/a | 71576789 | n/a | 3-cyclopropyl-4-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine | n/a | |
| 34 | O96017_ZAT | ZAT | n/a | 6328182 | CHEMBL142485 | 4,4'-DIACETYLDIPHENYLUREA-BIS(GUANYLHYDRAZONE) | n/a | |
| 35 | O96017_ZZK | ZZK | n/a | 44520783 | CHEMBL590335 | 4-[2-AMINO-5-(1,3-BENZODIOXOL-4-YL)PYRIDIN-3-YL]BENZAMIDE | n/a | |
| 36 | O96017_DB06486 | n/a | DB06486 | n/a | n/a | Enzastaurin | n/a | |
| 37 | O96017_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |