Gene name: LDHA
Protein name: L-lactate dehydrogenase A
List of molecules and drugs that interact with protein P00338
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P00338_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 2 | P00338_22Y | 22Y | n/a | 71677802 | CHEMBL2430735 | 3-(5-amino-6-{[(1R)-1-phenylethyl]amino}pyrazin-2-yl)-4-chlorobenzoic acid | n/a | |
| 3 | P00338_2OP | 2OP | DB14475 | 107689 | CHEMBL330546 | (2S)-2-HYDROXYPROPANOIC ACID | n/a | |
| 4 | P00338_36U | 36U | n/a | 75815443 | n/a | (5S)-2-[(2-chlorophenyl)sulfanyl]-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-one | n/a | |
| 5 | P00338_36V | 36V | n/a | n/a | n/a | trans-2-[(2-nitrophenyl)sulfanyl]-5-phenylcyclohexane-1,3-dione | n/a | |
| 6 | P00338_38K | 38K | n/a | 57334939 | CHEMBL3746548 | 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3-sulfamoylquinolin-4-yl]amino}benzoic acid | n/a | |
| 7 | P00338_38Q | 38Q | n/a | 57336253 | n/a | 3-{[3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl]amino}benzoic acid | n/a | |
| 8 | P00338_49C | 49C | n/a | 86277905 | n/a | (1R)-5'-[(2-chlorophenyl)sulfanyl]-4'-hydroxy-2,3-dihydrospiro[indene-1,2'-pyran]-6'(3'H)-one | n/a | |
| 9 | P00338_6EY | 6EY | n/a | 121596335 | n/a | (6R)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(3-hydroxyphenyl)-6-(thiophen-3-yl)-5,6-dihydropyridin-2(1H)-one | n/a | |
| 10 | P00338_88N | 88N | n/a | 56844254 | CHEMBL2059811 | {4-[4-({3-[(2-METHYL-1,3-BENZOTHIAZOL-6-YL)AMINO]-3-OXOPROPYL}AMINO)-4-OXOBUTYL]BENZYL}PROPANEDIOIC ACID | n/a | |
| 11 | P00338_9G9 | 9G9 | n/a | 10359012 | CHEMBL261367 | 5,5'-[(2R,3S)-2,3-dimethylbutane-1,4-diyl]bis(2H-1,3-benzodioxole) | n/a | |
| 12 | P00338_9Y1 | 9Y1 | n/a | 121461897 | CHEMBL4080650 | 2-[3-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid | n/a | |
| 13 | P00338_9Y7 | 9Y7 | n/a | n/a | CHEMBL4076973 | 2-{3-(3,4-difluorophenyl)-5-hydroxy-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid | n/a | |
| 14 | P00338_9YA | 9YA | n/a | 131955127 | CHEMBL4081890 | 2-{3-([1,1'-biphenyl]-3-yl)-5-(cyclopropylmethyl)-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid | n/a | |
| 15 | P00338_9YD | 9YD | n/a | n/a | CHEMBL4079370 | 2-[3-(3,4-difluorophenyl)-5-hydroxy-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid | n/a | |
| 16 | P00338_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 17 | P00338_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 18 | P00338_D0V | D0V | n/a | 134820916 | n/a | (2R)-5-[(2-chlorophenyl)sulfanyl]-6'-[(4-fluorophenyl)amino]-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro[2,2'-bipyridin]-6(1H)-one | n/a | |
| 19 | P00338_D0Y | D0Y | n/a | 134820915 | CHEMBL5177632 | (6R)-3-[(2-chlorophenyl)sulfanyl]-6-{3-[(4-fluorophenyl)amino]phenyl}-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one | n/a | |
| 20 | P00338_D3J | D3J | n/a | 134821711 | n/a | (2R)-5-[(2-chlorophenyl)sulfanyl]-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro[2,2'-bipyridin]-6(1H)-one | n/a | |
| 21 | P00338_D3S | D3S | n/a | 134821710 | n/a | (6S)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(2-hydroxyphenyl)-6-phenyl-5,6-dihydro-2H-pyran-2-one | n/a | |
| 22 | P00338_D47 | D47 | n/a | 134821709 | n/a | (3S,6S)-3-[(2-chlorophenyl)sulfanyl]-6-{6-[(4-fluorophenyl)amino]pyridin-2-yl}-6-(thiophen-3-yl)piperidine-2,4-dione | n/a | |
| 23 | P00338_D4A | D4A | n/a | 134821713 | n/a | (6R)-3-[(2-chlorophenyl)sulfanyl]-6-{6-[(4-fluorophenyl)amino]pyridin-2-yl}-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one | n/a | |
| 24 | P00338_D4J | D4J | n/a | 134821712 | n/a | (2S)-5-[(2-chlorophenyl)sulfanyl]-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro[2,2'-bipyridin]-6(1H)-one | n/a | |
| 25 | P00338_D4S | D4S | n/a | 134821708 | n/a | (6R)-6-(3-aminophenyl)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one | n/a | |
| 26 | P00338_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 27 | P00338_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 28 | P00338_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 29 | P00338_GN0 | GN0 | n/a | 121225870 | CHEMBL4065858 | (2~{R})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one | n/a | |
| 30 | P00338_GN2 | GN2 | n/a | 131801110 | CHEMBL4589484 | (2~{S})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one | n/a | |
| 31 | P00338_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 32 | P00338_KAN | KAN | DB01172 | 6032 | CHEMBL1384 | KANAMYCIN A | n/a | |
| 33 | P00338_L5K | L5K | n/a | 146160384 | n/a | ~{N}-[3-[(7-nitrodibenzofuran-2-yl)sulfonylamino]phenyl]-1-oxidanyl-cyclopropane-1-carboxamide | n/a | |
| 34 | P00338_L5N | L5N | n/a | 146160383 | n/a | 4-[[4-[(5-chloranylthiophen-2-yl)carbonylamino]-1,3-bis(oxidanylidene)isoindol-2-yl]methyl]benzoic acid | n/a | |
| 35 | P00338_LAC | LAC | DB03066 | 61503 | CHEMBL358850 | LACTIC ACID | n/a | |
| 36 | P00338_MLA | MLA | DB02175 | 867;23511544; | CHEMBL7942 | MALONIC ACID | n/a | |
| 37 | P00338_MLI | MLI | DB02201 | 9084 | n/a | MALONATE ION | n/a | |
| 38 | P00338_NAD | NAD | DB14128 | 5892;5288979;10897651;73415790; | CHEMBL1234613 | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | n/a | |
| 39 | P00338_NAI | NAI | DB00157 | 439153 | CHEMBL1234616 | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | n/a | |
| 40 | P00338_OXL | OXL | n/a | 71081 | n/a | OXALATE ION | n/a | |
| 41 | P00338_OXM | OXM | DB03940 | 974 | CHEMBL15976 | OXAMIC ACID | n/a | Ki(nM) = 26000.0 IC50(nM) = 57200.0 |
| 42 | P00338_P8M | P8M | n/a | 154585731 | CHEMBL4782843 | 2-{3-[3-(cyclopentylethynyl)-4-fluorophenyl]-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid | n/a | |
| 43 | P00338_P8V | P8V | n/a | 139465347 | CHEMBL4753379 | 2-[5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-3-{3-[(5-methylthiophen-2-yl)ethynyl]phenyl}-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid | n/a | |
| 44 | P00338_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 45 | P00338_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 46 | P00338_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 47 | P00338_TXD | TXD | n/a | 4369002 | n/a | 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | n/a | |
| 48 | P00338_W13 | W13 | n/a | 126843268 | n/a | (5R)-2-[(2-chlorophenyl)sulfanyl]-5-[2,6-dichloro-3-(tetrahydro-2H-pyran-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-one | n/a | |
| 49 | P00338_W31 | W31 | n/a | 126843267 | n/a | (1S)-1-phenylethyl (4-chloro-3-{[(4S)-4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohex-1-en-1-yl]sulfanyl}phenyl)acetate | n/a | |
| 50 | P00338_YOJ | YOJ | n/a | 155937498 | CHEMBL4850573 | 5-[(5'-{1-(4-carboxy-1,3-thiazol-2-yl)-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-3-yl}-2'-fluoro[1,1'-biphenyl]-4-yl)oxy]-1H-1,2,3-triazole-4-carboxylic acid | n/a | |
| 51 | P00338_ZHK | ZHK | n/a | 71447321;135566818; | n/a | (2R)-2-{[5-cyano-4-(3,4-dichlorophenyl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}-N-(4-sulfamoylphenyl)propanamide | n/a | |
| 52 | P00338_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 53 | P00338_ENA | ENA | DB02483 | 170119;131675359;137349265; | n/a | Etheno-NAD | n/a | |
| 54 | P00338_NCA | NCA | DB02701 | 936 | CHEMBL1140 | Nicotinamide | n/a | |
| 55 | P00338_DB09118 | n/a | DB09118 | n/a | n/a | Stiripentol | inhibitor | |
| 56 | P00338_DB09130 | n/a | DB09130 | n/a | n/a | Copper | n/a | |
| 57 | P00338_DB11638 | n/a | DB11638 | n/a | n/a | Artenimol | ligand |